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Active clinical trials for "Varicose Ulcer"

Results 201-210 of 303

Long-Term Follow-Up to the DEVO Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers

Venous Leg Ulcer

Observe the long-term (1-year) outcomes of Dermagraft, compared with conventional treatment of four-layer compression bandaging therapy alone, in subjects who completed the ABH-Dermagraft-001-08 study. Study Hypothesis: N/A (Long-term follow-up study)

Completed6 enrollment criteria

Negative Pressure Vs. Compression in Venous Ulcers

Varicose Ulcer

This study randomises patients with venous leg ulcers, to be managed either using conventional compression bandages or a bridged vacuum assisted closure system under compression.

Completed19 enrollment criteria

A Multicenter, Post Marketing Clinical Follow up (PMCF) Investigation to Evaluate the Performance...

Venous Leg Ulcer (VLU)

This investigation is a Post Marketing Follow-Up Study for Mepilex XT conducted as part of Mölnlycke Health Care's quality system. The primary objective is to evaluate the performance of the dressing when used as intended on exuding Venous Leg Ulcers (VLUs) in the inflammatory and granulating stages of the wound healing process.

Completed21 enrollment criteria

Transforming Nanoparticle Dressing For Management of Chronic Venous Ulcers

Chronic Venous Hypertension With Ulcer

The present randomized controlled study aims to evaluate the role of transforming nanoparticle dressing n management of chronic venous ulcers.

Completed2 enrollment criteria

A Post Marketing Study of Apligraf in Non-healing Wounds of Subjects With Venous Leg Ulcers

Venous Ulcer

The overall study objective is to use microarray technology to identify and characterize the gene expression of multiple relevant genes in biopsies of non-healing venous ulcers.

Completed21 enrollment criteria

Treatment Outcome of Autologous PRP Versus Conventional Therapy Among Patients With Chronic Venous...

Venous Leg Ulcer

The use of PRP has dramatically increased in the fields of orthopedics, spine surgery, reconstructive plastic surgery, oral and maxillofacial surgery, and dermatological indications. Nonetheless, its use in the treatment of wounds is not as widespread as in other fields. In this experimental study, the treatment outcome of autologous PRP was assessed in comparison to conventional therapy among patients with chronic venous leg ulcers.

Completed9 enrollment criteria

Effects of Local Insulin on Varicose Ulcers for Wound Healing

Chronic Venous DiseaseVaricose Ulcer3 more

A randomized, split-plot, double-blind, placebo-controlled trial. The varicose ulcer is divided into two (side A and B). Half of the wound's surface is treated locally with insulin (Glargine) applied at an approx depth of 3-4 mm. Treatment with insulin is administered for 7 days. Biopsy specimens of the two sides are obtained on days 0 and 7. A thermographic photograph of the wound is taken at days 0 and 7. The number of blood vessels and fibroplasia is evaluated as the main outcome.

Completed7 enrollment criteria

Haemodynamics Variations of Transcutaneous Oxygen in Patient With Areterio-venous Leg Ulcers Under...

Leg UlcerCompression; Vein

Arterio-venous leg ulcers are real problems when it comes to public health because it has a major cost and leads to social and professional handicap. The management of leg ulcers is not clear and can be venous compression or surgery. The aim of the study is to evaluate the variation of the transcutaneous oxygen with compression. The second aim is to see how tolerate is the compression and the quality of life.

Completed4 enrollment criteria

Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With...

Venous Leg UlcerChronic Venous Insufficiency3 more

The purpose of the study is to assess treatment tolerance and comfort in chronic VLUs after 4 weeks of treatment using a dual action pneumatic compression device.

Completed22 enrollment criteria

Study to Evaluate the Performance of AQUACEL® Extra™ in Venous Leg Ulcers

Leg Ulcer

Based upon the in-vitro data AQUACEL® Extra™ achieves a 39% increase in absorbency. As such it is anticipated that through improved exudate management a longer wear time will be achieved in the AQUACEL® Extra™ group compared to AQUACEL® in the management of chronic wounds such as venous leg ulcers.

Completed14 enrollment criteria
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