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Active clinical trials for "Strabismus"

Results 11-20 of 128

Peribulbar Rocuronium in Adult Strabismus Surgery

StrabismusRegional Anesthesia Morbidity1 more

This is a prospective randomized clinical study that will be carried on adult patients aged from 21-60 years and presented for strabismus surgery under peribulbar anesthesia. Patients will be excluded if they refused to participate or had a contraindication to peribulbar anesthesia. Patients will be randomly distributed into either control group in which peribulbar anesthesia will be performed by injection of 10 ml local anesthetic mixture composed of 4 ml of plain bupivacaine 0.5%, 4 ml of lidocaine 2% containing 50 IU, and 2 ml normal saline or rocuronium group which peribulbar anesthesia will be performed by injection of 10 ml local anesthetic mixture composed of 4 ml of plain bupivacaine 0.5%, 4 ml of lidocaine 2% containing 50 IU, and 0.06 mg/kg of rocuronium in 2 ml normal saline. Measurements will include; - Patient age, weight, height, gestational age, and gravidity. The duration of globe akinesia (primary outcome). The onset of lid and globe akinesia and the duration of lid akinesia The onset and duration of sensory block Time required to start the surgery Akinesia score The visual analog score (VAS) which is composed of 0-10 score will be used to assess the severity of postoperative pain (where 0=no pain and 10=severe pain), The VAS score will be evaluated 1 h, 2 h postoperative, then every 2 h till 12 h. Any patients with VAS score more than 4 received rescue analgesia in the form of 50 mg tramadol intravenous injection with the calculation of the time for the first call of postoperative analgesia. Any detected complication as nausea and vomiting, pain on injection, or increased intraocular tension.

Recruiting12 enrollment criteria

The Alaska Oculocardiac Reflex Study

BradycardiaStrabismus

Observation study monitoring vital signs and anesthetic variables particularly heart rate during prospective, ocular manipulation and specifically uniform tension on extra ocular muscles during strabismus surgery. *IRB approval from 1992 covered in letter from then IRB chair Dr. Judith Whitcomb, Anchorage, Alaska (letter 10/2020).*

Recruiting2 enrollment criteria

Combination of Orbital Compression Surgery and Strabismus Surgery for Thyroid Associated Ophthalmopathy...

Thyroid Associated Ophthalmopathy

The purpose of this study is to determine whether combination of orbital compression surgery with strabismus surgery is better than strabismus surgery after orbital compression surgery in the treatment of moderate-to-severe thyroid associated ophthalmopathy

Not yet recruiting6 enrollment criteria

Amblyopia and Strabismus Detection Using Retinal Birefringence Imaging

AmblyopiaStrabismus

The purpose of this project is to compare the accuracy of two products at detecting amblyopia and strabismus in children. The devices will be Rebiscan's "blinq" (Pediatric Vision Scanner; PVS) and Rebiscan's RBI (Retinal Birefringence Imager).

Recruiting4 enrollment criteria

Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy

AmblyopiaStrabismus

Amblyopia and strabismus are characterized by a reduction in visual acuity, contrast sensitivity, grating acuity, vernier acuity, reading difficulties and binocular visual function deficits. Treated patients have residual visual function deficits. The purpose of the current study is to quantify various visual functions in amblyopic and strabismic participants at baseline, during and at the completion of treatment.

Recruiting2 enrollment criteria

Intraoperative OCT Guidance of Intraocular Surgery II

Macular HolesEpiretinal Membrane8 more

The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes. The investigators believe this technology will enable novel ophthalmic and other microsurgeries not possible due to current limitations in surgical visualization.

Recruiting8 enrollment criteria

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

StrabismusNystagmus1 more

Strabismus (misalignment of the eyes) often runs in families. In this study, the investigators are looking for genetic variants associated with strabismus and nystagmus. Three types of subects will be enrolled: (1) Families with at least 3 members with strabismus, (2) individuals with infantile esotropia and their parents and siblings, and (3) individuals with infantile nystagmus and their parents. Whole exome and/or whole genome sequencing will be used to identify genetic variants shared by family members with strabismus and to identify genetic causes of nystagmus.

Recruiting4 enrollment criteria

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated...

Congenital Fibrosis of Extraocular MusclesDuane Retraction Syndrome26 more

The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.

Recruiting2 enrollment criteria

Performance and Safety Evaluation of the S360 Medical Device Software.

Binocular Vision DisorderBinocular Eye Movement Disorder1 more

The aim of this interventional, cross-sectional study is to evaluate the performance and the safety of the medical device software S360. This clinical investigation is performed in order to demonstrate the conformity of the medical device, when operating under the normal conditions of its intended use, in accordance with the General Safety and Performance Requirements pertaining to clinical evaluation of the device regarding the Medical Device Regulation (MDR) 2017/745 (EU).

Not yet recruiting16 enrollment criteria

Dichoptic Virtual Reality Therapy for Amblyopia in Adults

AmblyopiaAnisometropia1 more

This was a randomized, masked, controlled study of the effect of a virtual reality, binocular, 3-dimensional video game on visual acuity and stereopsis in adult patients with amblyopia. The trial has been halted as of June 2016 and will not be evaluating any new subjects for enrollment.

Terminated15 enrollment criteria
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