REsting and Stimulus-based Paradigms to Detect Organized NetworkS and Predict Emergence of Consciousness...
Consciousness DisorderComa2 moreThe aim of this study is to assess the utility of advanced magnetic resonance imaging (MRI) and electroencephalographic (EEG) technologies for predicting functional outcomes in patients with severe traumatic brain injury (TBI).
Olfactory Deficits in Neurologic Disease
Alzheimer DiseaseTraumatic Brain Injury4 moreThe goal of this study is to examine olfactory function in preclinical subjects or individuals with neurological diseases such as Probable Alzheimer's Disease (PRAD), Frontotemporal Dementias (FTD), Dementia with Lewy Bodies (DLB), Traumatic Brain Injury (TBI), and Amyotrophic Lateral Sclerosis (ALS).
Intracranial Pressure (ICP) Monitoring Following Traumatic Brain Injury (TBI)
Traumatic Brain InjuryThe aim of this retrospective cohort study is to evaluate complications rates, indications, and the utility of follow-up imaging studies of ICP measurement in severe TBI patients.
Evaluation of qSOFA in Neurosurgical Patients
Brain InjuriesBrain Trauma1 moreThe aim of the study is to look if Quick Sequential Organ Failure Assessment Score score in detecting a eary Sepsis is afflicted by neurosurgical disorders
Coagulopathy on the First Postoperative Day Predicts the Long-term Survival of Traumatic Brain Injury...
Traumatic Brain InjuryCoagulation DisorderThe purpose of this study was to identify the relationship between coagulopathy during the perioperative period (before the operation and on the first day after the operation) and the long-term survival of traumatic brain injury patients undergoing surgery, as well as to explore the predisposing risk factors that may cause perioperative coagulopathy.
Validation of Brain Function Assessment Algorithm for mTBI/Concussion in College Athletes
Brain InjuriesTraumatic8 moreThis study is Part 1 of data collection from 18-25 years old subject population for validation of previously derived algorithms. This data will be combined with that collected under NCT03671083 (Part 2 with subject age range 13-25 years) for the final analyses of validation of the algorithms.
Continuous Quantified EEG in NeuroIntensive Care
ComaTraumatic Brain Injury2 moreTo evaluate the ability of NICU staff to interpret, before and after a training period, symmetry, sedation level, seizures activities and artefact on continuous cEEG/qEEG tracings.
Reliability of the Melbourne Assessment
Cerebral PalsyStroke3 moreThe aim of the study is to investigate the reliability of the Melbourne Assessment.
Optic Nerve Ultrasound in Severe Traumatic Injury
Traumatic Brain InjuryIntracranial HypertensionProspective study of diagnostic accuracy of optic nerve sheath diameter measurement (index study) in traumatic brain injury with simultaneous invasive intracranial pressure monitoring as the reference standard.
Optimizing Drug Doses in Critically Ill
Traumatic Brain InjuryKidney FunctionalThe primary objectives of this study are to examine whether augmented renal clearance (ARC) compromises renally eliminated drug therapeutic serum concentrations in patients with traumatic brain injury (TBI) and to estimate the optimal dose needed to achieve therapeutic serum concentrations of the probe medication levetiracetam in patients with TBI.