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Active clinical trials for "Tobacco Use Disorder"

Results 721-730 of 859

Evaluation of Tobacco Treatment Strategies for Inpatient Psychiatry

Tobacco Dependence

This study aims to evaluate, in a randomized controlled trial, tobacco treatments of varying intensities for smokers hospitalized on acute psychiatric inpatient units.

Unknown status2 enrollment criteria

Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation

Tobacco Use Disorder

The purpose of this study is to compare the effects of bupropion + placebo to bupropion + naltrexone as treatments to help smokers quit.

Unknown status24 enrollment criteria

Impact of Nicotine Messaging on Nicotine Beliefs and Tobacco Use Behavior

Nicotine DependenceCigarettes

This is a 2-arm, randomized controlled, population based trial to test the impact of multiple exposures to brief nicotine corrective messages among adult tobacco cigarette smokers and non-smokers followed in waves over 12 weeks. The primary outcome, assessed at wave 1 (baseline), wave 2 (weeks 5-6), and wave 4 (weeks 11-13) is nicotine beliefs. Secondary outcomes assessed at the same time points include intention to use nicotine/tobacco products and nicotine/tobacco use.

Completed5 enrollment criteria

Targeted Intervention for Bipolar Smokers

Nicotine DependenceBipolar Disorder

The purpose of this research is to develop and test a new type of smoking cessation counseling for individuals with bipolar disorder.

Unknown status9 enrollment criteria

Drug /Cue Interactions In Alcohol-Tobacco Comorbidity

Nicotine Dependence

The purpose of this study is to determine how people react to different combinations of alcohol and nicotine.

Completed3 enrollment criteria

Prevention of Nicotine Abstinence in Critically Ill Patients After Major Surgery

Nicotine Dependence

The primary objective of this study is to determine whether the application of transdermal nicotine patches in critically ill patients after major surgery with nicotine abstinence condition is associated with a lower incidence of delirium.

Completed14 enrollment criteria

Promoting Home Smoking Restrictions: Biomarker Feedback to Smoking and Non-Smoking Adults

Smoking CessationTobacco Use Disorder

This study is directed at decreasing home environmental tobacco smoking (ETS) exposure with a novel approach of adoption of home smoking restrictions. This will be done by providing the cohabitating smoker and non-smoker with biomarker feedback documenting exposure to ETS. The intent is to identify an intervention strategy(ies) to reduce ETS exposure.

Completed9 enrollment criteria

Flexiquit+: Web Program to Promote Smoking Cessation in Sexual and Gender Minority Young Adult Smokers...

Tobacco Use Disorder

This phase I trial studies how well Flexiquit+ helps young adult smokers who identify as a sexual and/or gender minority to quit or cut down on smoking. Flexiquit+ is an avatar-led, web-based intervention that can help smokers quit or cut back on how much they smoke cigarettes and/or vape, reducing their chances of developing tobacco-related health conditions.

Completed14 enrollment criteria

Efficacy and Safety of Combination EMB-001 as a Potential Smoking Cessation Treatment

Smoking CessationTobacco Use Disorder

This open-label study will evaluate EMB-001, comprised of metyrapone, a cortisol synthesis inhibitor marketed as a diagnostic drug for testing hypothalamic-pituitary-adrenal (HPA) axis function, combined with oxazepam, an anxiolytic and sedative/hypnotic benzodiazepine, to help smokers abstain from smoking during a 12-week trial period.

Unknown status37 enrollment criteria

Effects of Stimulant Dependence on Human Striatal Dopamine System - 15

Amphetamine-Related DisordersTobacco Use Disorder

The purpose of this study is to determine whether DAT availability, assessed by WIN binding, in the striatum is altered in cocaine or methamphetamine dependence. To determine whether DA synthesis capacity, assessed by FDOPA uptake, in the striatum is altered in Coc or Meth dependence. To determine whether the PET tracers, WIN or FDOPA, will differentiate Meth induced alterations from those induced by Coc use. To determine whether the PET characterization of striatal alterations observed at 3-5 days since last drug use persists at least 3 months after last drug use.

Unknown status2 enrollment criteria
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