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Active clinical trials for "Tourette Syndrome"

Results 41-50 of 201

Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome

Tourette Syndrome

This is a Phase 2, double-blind, placebo-controlled, randomized withdrawal study to evaluate the safety and maintenance of efficacy of an optimized once-daily (qd) dose of NBI-98854 in pediatric subjects with TS.

Terminated19 enrollment criteria

Open-label Extension Study of Pramipexole in the Treatment of Children and Adolescents With Tourette...

Tourette Syndrome

The primary objective of this open-label, flexible dose study is to assess the safety and efficacy of pramipexole over a 24-week period in children and adolescents (age 6-17 years inclusive) diagnosed with Tourette Syndrome according to Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) criteria and who have completed either Study 248.641 (NCT 00681863) or 248.644 (NCT 00558467).

Terminated20 enrollment criteria

Trial to Evaluate the Long-term Efficacy of Oral Aripiprazole in the Treatment of Pediatric Participants...

Tourette's Disorder (TD)

To evaluate the long-term efficacy of oral aripiprazole in pediatric participants for the treatment of Tourette's Disorder (TD).

Terminated27 enrollment criteria

Aripiprazole in the Treatment of Tourette's Syndrome

Tourette's Syndrome

This is an open-label, flexible dose study designed to evaluate the safety and efficacy of aripiprazole in TS (or chronic tic disorder) subjects with or without associated OC symptoms and with or without ADHD symptoms.

Terminated13 enrollment criteria

FAAH Inhibitor Trial for Adults With Tourette Syndrome

Tourette Syndrome

The purpose of this trial is to examine the safety, tolerability and feasibility in the use of a FAAH inhibitor for the treatment of adults with Tourette syndrome.

Terminated12 enrollment criteria

Pilot Study of the Modified Atkins Diet for Tourette Syndrome

Tourette Syndrome

Pharmacotherapy has long been considered the primary approach for tic suppression in Tourette syndrome (TS). Unfortunately, medications are often ineffective and frequently have significant side-effects. This is a pilot therapeutic study using a dietary approach, the modified Atkins diet (MAD). The goal of this study is to establish the safety, tolerability, and efficacy of dietary therapy in patients with TS ("proof of concept") and to determine whether this intervention is worthy of evaluation in large-scale clinical trials. The modified Atkins diet mimics the well established ketogenic diet, but in a less-restrictive dietary manner. Dietary approaches using the MAD/ketogenic diet are currently under investigation for neurological conditions other than epilepsy, including Alzheimer disease, headaches, autism, narcolepsy, brain tumors, traumatic brain injury, Parkinson's disease, and depression.

Terminated11 enrollment criteria

Safety Study of Galantamine in Tic Disorders

Tourette's SyndromeMotor Tic Disorder1 more

The purpose of this study is to determine the safety, tolerability and efficacy of galantamine in tic disorders. The impact of galantamine on commonly associated behaviors (i.e. attention, obsessions, etc.) will also be examined.

Terminated5 enrollment criteria

Sensory Symptoms in Tourette Syndrome

Tourette Syndrome

Patients with tics will be asked to complete a series of validated questionnaires (in electronic and/or paper format) regarding symptoms and conditions often associated with Tourette syndrome, including premonitory urges, sensory experiences, inattention, obsessive-compulsive tendencies, anxiety, and depression. Participants will also be asked to complete a quality of life assessment. This series of questionnaires will be administered annually.

Enrolling by invitation5 enrollment criteria

Repetitive Transcranial Magnetic Stimulation of the Posterior Parietal Cortex in Patients Suffering...

Gilles de la Tourette SyndromeTics

Repetitive transcranial stimulation (rTMS) of the posterior parietal cortex will be applied daily over five days in adult Gilles de la Tourette patients. This approach aims at reducing premonitory sensations believed to induce tics. Patients will be randomized to an active or placebo (sham) group in a crossover design.

Terminated12 enrollment criteria

Assessment of Children With Tic Onset in the Past 6 Months

Tourette SyndromeTourette's Disorder4 more

The purpose of this research is to study why most children who have tics never develop Tourette syndrome but some do. In other words, we aim to find features that may predict whose tics will go away and whose tics will continue or worsen, in children ages 5 through 10 years whose first tic occurred within the past 9 months.

Enrolling by invitation9 enrollment criteria
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