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Active clinical trials for "Tourette Syndrome"

Results 91-100 of 201

Efficacy & Safety Study of Once-weekly Oral Aripiprazole in Children and Adolescents With Tourette's...

Tourette's Disorder

The goal of the current trial is to determine efficacy and safety of once-weekly aripiprazole in reducing Total Tic Severity (TTS) score in children and adolescents with Tourette's Disorder.

Completed25 enrollment criteria

Aripiprazole in Children and Adolescents With Chronic Tic Disorder or Tourette's Disorder

Chronic Motor or Vocal Tic DisorderTourette's Disorder

The purpose of this trial is to demonstrate the efficacy and safety of aripiprazole in children and adolescents aged 6~18 years with chronic tic disorders or Tourette's disorder

Completed12 enrollment criteria

Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to...

Tourette Syndrome

A randomized, double-blind, placebo-controlled, flexible dose study to evaluate efficacy and safety of Pramipexole versus placebo for 6 weeks in children (age 6-17) diagnosed with Tourette Disorder according to DSM IV criteria. The primary efficacy measure will be the Total Tic Score (TTS) of the Yale Global Tic Severity Scale (YGTSS) at 6 weeks.

Completed25 enrollment criteria

Methylphenidate for Treating Children With ADHD and Tourette Syndrome

Attention Deficit Disorder With HyperactivityTourette Syndrome

This study will evaluate the safety and effectiveness of methylphenidate in treating attention deficit hyperactivity disorder in children with both attention deficit hyperactivity disorder and Tourette syndrome.

Completed5 enrollment criteria

Open Label Trial of Aripiprazole in Children and Adolescents With Tourette's Disorder

Tourette's SyndromeTic Disorders

The purpose of this study is to determine if Abilify will reduce tics (repetitive, uncontrollable movements or vocalizations) in children and adolescents ages 7-18 with Tourette's Disorder (TD) or a chronic motor tic disorder (either repetitive, uncontrollable movements or vocalizations).

Completed22 enrollment criteria

Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome...

Tourette Syndrome

OBJECTIVES: I. Determine whether the time period between randomization and endpoint is longer in the short term pimozide therapy or longer term therapy in patients with Tourette syndrome. II. Determine whether tic severity, medication side effects, academic performance and psychosocial functioning are better in the short term pimozide therapy or longer term pimozide therapy.

Completed2 enrollment criteria

Objective Characterizatoion of Repetitive Behaviors

OCDTic Disorders1 more

Introduction: Repetitive behaviors (RB) constitute a broad range of symptoms across different psychiatric/neurologic disorders. The most famous are stereotypies (found in autism), compulsions (found in obsessive-compulsive-disorder, OCD) and tics (found in Gilles de la Tourette syndrome, GTS). For some patients, it is sometime difficult to distinguish the nature of the repetitive behaviors presented, however this distinction is crucial in order to chose the appropriate treatment. Aim: In our study, the investigators will try to define electrophysiological and accelerometric marker of both OCD and tics to allow objective distinction between both tics and compulsions. Method: Subjects: Both OCD and GTS patients will be recruited, 25 patients in each group. Protocol: our study protocol will involve two step: a step in laboratory, another step at patient home. first step: both patients group will be recorded through a high density EEG and a portative EEG while doing a task of symptom provocation. Then they will get an anatomical MRI for source recontruction. Finally, the patients will have to mimic their symptom while wearing an accelerometer (a smartwatch). second step: both patient groups will be recorded at home through a portative EEG while tagging their symptom through a smartwatch (also used for accelerometry). After the recording, the patients will keep the smartwatch for 2 weeks, still tagging their sympoms (compulsions or tics).

Not yet recruiting11 enrollment criteria

Ecopipam Tablets to Study Tourette's Syndrome in Children and Adolescents

Tourette Syndrome

This study evaluates the effect of ecopipam tablets in children and adolescents in the treatment of Tourette's Syndrome (TS). Half of the participants will receive ecopipam tablets, while the other half will receive matching placebo tablets

Completed16 enrollment criteria

Ecopipam Tablets to Study Tourette Syndrome in Children and Adolescents - Open Label Extension

Tourette Syndrome in ChildrenTourette Syndrome in Adolescence

This study is an international, multicenter, open-label, long term extension study evaluating the safety of ecopipam tablets for the treatment of children and adolescent subjects with Tourette Syndrome.

Completed8 enrollment criteria

An Exploratory Study of Continuous Theta Burst Stimulation (cTBS) Based on fMRI in the Treatment...

Tic DisordersTourette Syndrome

continuous theta burst stimulation (cTBS) is a safe and effective device for Gilles de la Tourette's syndrome treatment. GPi is an agreed curative target of deep brain stimulation. GPi-based functional connectivity peak voxel in the SMA can be the cTBS target.

Completed9 enrollment criteria
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