Dynamic Airway CT is Diagnostic for Tracheomalacia in Children
TracheomalaciaThe purpose of this pilot interventional study is to evaluate the use of Dynamic Airway Computed Tomography (DA-CT) for diagnosis of tracheomalacia in children 0-18 years for whom flexible bronchoscopy has been performed. The primary aims are to evaluate the diagnostic accuracy, image quality, and radiation exposure of DA-CT as a potential noninvasive alternative to the gold standard of flexible bronchoscopy in the diagnosis of tracheomalacia. The results from this pilot study will help to estimate sample size for a larger-scale study with more precise estimates of DA-CT diagnostic potential.
A Study to Assess the Safety, Tolerability and Potential Efficacy of a Tracheal Replacement Consisting...
TracheomalaciaTracheal StenosisThis is a phase I study to evaluate the safety, efficacy and tolerability of a novel tracheal replacement therapy using cadaveric de-cellularised tracheal scaffold and patients' own mesenchymal cells isolated from a sample of their bone marrow in patients' who suffer from severe tracheal malacia or stenosis.
Tracheobronchomalacia: Treatment Outcomes
TracheomalaciaTracheobronchomalaciaThe purpose of this study is to evaluate respiratory symptoms and their impact in the quality of life and after treatment of the respiratory condition (tracheobronchomalacia - TBM).
Tracheal Mechanics During Bronchoscopy
TracheomalaciaTracheobronchomalaciaThe main purpose of this study is use a new type of measurement to help decide what kind of therapy would help people with a collapsing windpipe or tracheomalacia.