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Active clinical trials for "Headache"

Results 1041-1050 of 1078

Pathway CH S&E Registry

Cluster Headache

Monitor the safety and performance of the Pulsante Microstimulator System.

Unknown status4 enrollment criteria

Primary Headache and Psychological Factors, Mental Functioning and Attachment Modalities.

Primary Headache Disorder

The World Health Organization (WHO) ranks headache among the top 20 causes of disability in the world. Primary headaches (with no known organic cause) account for 90% of these conditions. INSERM estimates that 15% of the general population is concerned. WHO estimates that 1.7-4% of the global adult population is affected by headache for at least 15 days a month. Headaches are disabling, for patients (pain, suffering, fatigue, unavailability ...) but also for society (socio-economic cost as frequent work stoppages and drug costs). They are a public health problem. In 2002, the High Authority of Health published its recommendations for the diagnosis and management of migraine patients. In addition, the French Society for Migraine and Headache Studies updated these recommendations in 2013. They are focused on the medical management offered by doctors and pharmacists. However, the professionals in daily contact with the subjects know that the dimension psychic plays an important role in the etiology of headaches.

Unknown status2 enrollment criteria

A Clinical Observation on Neuropsychology and Electrophysiology in Headache Patinets With Myofascial...

Myofascial Trigger Points

To study the clinical characteristics of headache patients with pericranial myofascial trigger points(MTrPs),and to explore the possible pathogenesis of MTrPs,investigators hope to find the possible electrical biomarkers for clinical diagnosis and treatment, and to improve the effect of headache treatment.

Unknown status2 enrollment criteria

Salivary Inflammatory Markers in Tension Type Headache and Migraine

MigraineTension-Type Headache

Data role of salivary inflammatory markers in migraine and Tension Type headache (TTH) are lacking. Τhe investigators studied whether headache attacks are associated with changes in C reactive protein (CRP), Interleukin -1β and Interleukin -6 in saliva in patients with Tension Type Headache and Migraine and age matched healthy controls . Τhe investigators, also investigated whether these markers could be influenced by comorbidities such as depression and anxiety.

Unknown status11 enrollment criteria

MRA/fMRI Study of Spontaneous Migraine

Headache Versus Non-headache Day

The purpose of this study is to examine migraineurs during spontaneous migraine attacks without aura, using high resolution magnetic resonance imaging (MRI), to study following: Changes in resting state blood-oxygenation-level-dependent-signal (BOLD-signal) using functional MRI (fMRI). Changes in circumferences of intra- and extracranial arteries using MR-angiography (MRA). Changes in regional and global cerebral blood flow (CBF) using the arterial spin labeling (ASL) method. Moreover to perform diffusion tensor imaging (DTI) scans during spontaneous migraine attacks. The migraine specific drug sumatriptan will be given to relieve pain and the effect will be registered using MRA and fMRI if possible.

Unknown status8 enrollment criteria

Identification of Inflammatory Markers in Migraine Patients

InflammationMigraine1 more

Migraine is prevalent in 10-12% of the population. It involves the development of a cranial perivascular neurogenic inflammation. Recent information suggests that migraine might be a risk factor to stroke. The possible mechanisms that might relate migraine and stroke are: 1. Migraineous infarction 2. A primary endothelial disorder. 3. Genetic relation 4. An ongoing inflammatory process. C reactive protein (CRP) is a sensitive marker for an inflammatory process.The data on the relation of migraine to inflammation is limited. The aim of the current study is to assess inflammatory factors as possible markers for migraine.

Unknown status7 enrollment criteria

QST, Blink Reflex and Nociceptive Flexion Reflex in Headache

Head Pain

The aim of this study is to compare central and peripheric sensitization in headache patients at Baseline (T0) and 1 month after (T1) a treatment with an anti-CGRP (Fremanezumab-Ajovy).

Unknown status5 enrollment criteria

Effects of Multimodal Treatment of Headache in a Day Clinic Service

Headache Disorders

The observational study aims to investigate the effects of a multimodal treatment program for headache patients in a day clinic service. The setting provides one week of treatment including a combination of medical consultation, physiotherapy, psychological therapy, occupational therapy, progressive muscle relaxation and disease specific education. Outcome measures are the disease-specific impact on daily activities, general quality of life, psychological impact and headache frequency. Moreover, the study sought to identify parameters that best predict efficacy of the intervention. Therefore, standardized questionnaires are established in three points in time, to evaluate the pre- and post-treatment status.

Unknown status4 enrollment criteria

Test-Retest Reliability of the German Version of the Headache Disability Questionnaire (HDQ).

Headache Disorders

a translated and cultural adapted version of the HDQ will be tested on two occasions with headache patients who are currently in physiotherapeutic treatment due to their headache condition

Unknown status7 enrollment criteria

Direct Access to MRI and Neurology Referrals for the Management of Patients With Chronic Headache....

Chronic Headache

This study aims to evaluate whether direct access from General Practitioners (GPs) to Magnetic Resonance Imaging (MRI) for patients with chronic headache decreases overall NHS costs and increases patient satisfaction compared to clinical practice with referral to Neurology Services.

Unknown status9 enrollment criteria
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