Study of Duloxetine in Elderly Patients With Major Depressive Disorder
DepressionCognitionA study of the safety and efficacy of duloxetine in elderly patients (greater than 65 years old) with major depressive disorder
Safety and Efficacy Trial of the Use of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Patients...
Bipolar DisorderDepression1 moreThe purpose of this study is to evaluate the efficacy and safety of quetiapine in the treatment of a major depressive episode in patients with bipolar disorder.
Efficacy of Paroxetine in the Prevention of Depressive Syndrome in Patients With Chronic Hepatitis...
Chronic Hepatitis CDepression is a common side effect of interferon in the treatment of chronic hepatitis C. The aim of this study is to assess the efficacy and safety of paroxetine, an antidepressant agent, in the prevention of depression induced by PEG-interferon given for the treatment of chronic hepatitis C.
Quantitative EEG (QEEG) as a Predictor of Treatment Outcome in Depression
Major Depressive DisorderThe purpose of the study is to try to see if antidepressant medications cause changes in QEEG measurements in the brain. QEEG is a mathematical analysis of electrical currents in the brain using electrodes placed on the scalp. Previous studies have shown that mood improvement (clinical response) caused by antidepressant medications was preceded by changes in QEEG measurements in the brain.
A United States Study of Corlux for Psychotic Symptoms in Psychotic Major Depression
Major Depressive DisorderPsychotic DisordersCorlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol. Under normal conditions, cortisol and other hormones are created by the body in response to physical and emotional stress, triggering a healthy stress response. People who suffer from psychotic major depression may have unusually high levels of cortisol circulating within them or abnormal patterns of cortisol levels, overloading the stress response mechanism and causing symptoms of psychosis such as delusional thoughts or hallucinations. If Corlux can keep the body's cortisol receptors from being overloaded, the stress response system may return to normal function, which may result in improvement of symptoms. The purpose of this 56 day study is to learn the safety and effectiveness of Corlux in patients who have been diagnosed with psychotic major depression (PMD).
Olanzapine Versus Active Comparator in the Treatment of Depression in Patients With Schizophrenia...
DepressionSchizophrenia1 moreThis is a research study comparing the safety and efficacy of two active study medications
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-068)(COMPLETED)
Major Depressive DisorderA clinical study to determine the efficacy and safety of an investigational medication (MK0869) in the treatment of depression.
Long Term Treatment of Patients With Major Depressive Disorder With MK0869 (0869-065)(COMPLETED)...
Major Depressive DisorderA clinical study to determine the efficacy and safety of an investigational medication (MK0869) in the treatment of depression.
Treatment of Depression in Patients With PTSD
PTSDDepressionPost-traumatic stress disorder is a mental health problem of enormous proportion within the VA system for both male and female veterans. The 40 percent of veterans with PTSD and concurrent clinically significant depression are particularly difficult to treat. Effective and efficient treatment of veterans with this combination of disorders would be of benefit to a significant number of veterans.
Magnetic Stimulation Therapy for Treating Vascular Depression
Depressive DisorderDepressionThis 12-week study will evaluate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) of the brain, followed by citalopram (Celexa®), for treatment of depression associated with small vascular lesions in the brain (vascular depression).