Febrile Infants - Diagnostic Assessment and Outcome
MeningitisBacterial2 moreThe purpose of this study is to assess how clinicians apply guidance in the assessment of febrile infants presenting the the Emergency Department. The measurable outcomes are: Primary Objective Report the rates of serious and invasive bacterial infections in febrile infants Secondary Objectives Report on the predictive value of different clinical features for predicting bacterial infections. Report on the value of biomarkers for predicting serious and invasive bacterial infections. Assess the performance of clinical practice guidelines for the assessment of febrile infants.
Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station...
Urinary Tract InfectionDiabetes Mellitus9 moreThe study objective is to satisfy the testing requirements for the Qualcomm Tricorder XPRIZE Competition. This requires an oversight model using the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station to continuously monitor the patient's five core vital signs and to detect the health conditions required by the competition.
Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients
PneumoniaAbdominal Infection1 moreThe investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.
Lower Urinary Tract Infection (UTI) Evaluation in Women With Uterine Leiomyomata
Urinary Tract InfectionLeiomyomaTo the investigators knowledge there is no research data published to date regarding the lower urinary tract symptoms in women with leiomyomas. The primary aims of this study are: To determine prevalence of lower urinary tract symptoms in patients who present for care for symptomatic leiomyomata. To compare change in lower urinary tract symptoms within treatment groups measured by the UDI-6 total before and at six months after three common treatments for symptomatic uterine fibroids including: hysterectomy, myomectomy, or uterine artery embolization. The study proposed here will hopefully answer the question if one particular therapy is appropriate to treat fibroids and relieve lower urinary tract symptoms.
A Biochip for Rapid Diagnosis of Complicated Urinary Tract Infection
Urinary Tract InfectionsBladder1 moreThe purpose of this proposal is clinical validation of an electrochemical biochip for rapid pathogen identification and antibiotic susceptibility determination.
The Significance of Funguria in Hospitalized Patients
Urinary Tract InfectionsThis investigation is a epidemiologic case-control study of the risk factors associated with nosocomial funguria (fungi in the urine).
Extended Spectrum Betalactamase Producing Bacteria; Epidemiology and Treatment in Non-hospitalized...
Urinary Tract InfectionInfection Due to ESBL Bacteria1 moreThis project aims at investigating the duration of human fecal carriage of bacteria harboring plasmid-borne resistance genes expressing Extended Spectrum beta-lactamases (ESBL), risk factors for infections with such bacteria and persistence, mobility and spread of ESBL in the environment and within households. It also aims to compare different methods of detecting ESBL carriage and treat patients with urinary tract infection caused by these bacteria.
Diagnosis of Subclinical Urinary Tract Infections Using Advanced Microbiome Survey Techniques in...
Urinary Tract InfectionThe purpose of this study is to see if the investigators can identify early those patients who are admitted to the hospital and have a urinary tract infection (UTI) or those patients that develop a UTI during their hospitalization.
Evaluation of Immunological Disorders of T Lymphocytes and Endocrinological Disorders as Pathogen...
The Follow-up Duration Was 1-8 Years.The Main Reasons Behind Visiting the Hospital Were Recurrent Urinary Tract Infection,9 moreBackground: Squamous metaplasia refers to the pathological transformation of the urothelium leading to non-keratinised stratified squamous metaplasia (N-KSM). Objective: To present the investigators experiences in the diagnosis and treatment of N-KSM of the urinary bladder in children.
Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection
Acute PyelonephritisHypothesis: Administration of corticoids (dexamethasone) together with the conventional antibiotherapy in the acute phase of a febrile urinary tract infection could reduce the risk of renal scarring after 6 months of the primo-infection. Primary objectives:To evaluate the reduction in incidence of renal scarring after 6 months of a acute pyelonephritis between the control group (conventional therapy plus placebo) and intervention group (conventional therapy plus dexamethasone. Design: Multicentre randomized clinical trial,placebo controled, including children between 2 months and 14 years with a acute pyelonephritis proven by a acute phase DMSA (dimethylsuccinic acid ). A total of 180 children in to parallel groups (intervention and placebo) will be included.