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Active clinical trials for "Uterine Neoplasms"

Results 71-80 of 207

A Trial of Atezolizumab and Vigil in Patients With Advanced Gynecological Cancers

Advanced Gynecological CancersOvarian Cancer2 more

The clinical trial was a companion study to protocol CL-PTL-119 (A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of Vigil Engineered Autologous Tumor Cell Immunotherapy in Subjects with Stage IIIb-IV Ovarian Cancer in Clinical Complete Response following Surgery and Primary Chemotherapy (VITAL) NCT02346747). Participants who had investigational product (Vigil) successfully made but were not eligible to enroll onto the VITAL study or previously randomized to placebo were given the opportunity to participate in this protocol. The main goal of this clinical trial was to determine the safety of combining Vigil therapy with atezolizumab.

Completed61 enrollment criteria

Study of Pembrolizumab, Radiation and Immune Modulatory Cocktail in Cervical/Uterine Cancer

Cervical CancerEndometrial Cancer1 more

This is a Phase II study in patients with advanced and/refractory cervical cancer, endometrial carcinoma or uterine sarcoma. Patients will be treated with an immunomodulatory cocktail (Vitamin D, aspirin, Cyclophosphamide and Lansoprazole), followed by pembrolizumab, combined with radiation. In addition, patients will take Curcumin, a food supplement.

Completed11 enrollment criteria

Feasibility Study: Accuracy of Biomarker in Detection of Endometrial Cancer

Uterine CancerEndometrial Cancer

This study aims at developing an accurate, simple, and cost-effective method for screening and early detection of uterine cancers

Terminated4 enrollment criteria

A Trial for Patients With Advanced/Recurrent Endometrial Cancer

NeoplasmsNeoplasms by Site11 more

The intent of this protocol is to screen a new agent for activity in patients with advanced or recurrent endometrial carcinoma. This phase II trial is studying how well pemetrexed disodium works in treating patients with advanced or recurrent endometrial carcinoma.

Completed14 enrollment criteria

Adjuvant Chemotherapy for High Risk Uterine Leiomyosarcoma

LeiomyosarcomaUterine Neoplasm

The purpose of this trial is to study the benefits of giving chemotherapy to women after they have had surgical resection of their primary disease and have no evidence of disease remaining(known as adjuvant therapy). The major objective of this study is to determine the progression free survival. The goal is to prevent relapse or recurrence of their uterine leiomyosarcoma.

Completed19 enrollment criteria

Comparison Study in the Treatment of Uterine Fibroids Uterine Fibroid Embolization Using BeadBlock™...

LeiomyomaLeiomyomatosis1 more

A double arm (non-inferiority) 44 patient study to assess the performance of BeadBlock™ in the treatment of uterine fibroids by embolization with respect to clinical & imaging outcome with comparison of primary safety endpoints to Embosphere.

Completed19 enrollment criteria

A Trial for Patients With Advanced/Recurrent Cervical Cancer

Cervical Intraepithelial NeoplasiaUterine Neoplasms2 more

This phase II trial is studying the antitumor activity of single agent pemetrexed 900mg/m2 IV over 10 minutes in patients with recurrent cervical cancer.

Completed11 enrollment criteria

Acupuncture for Women's Health Conditions

Ovarian NeoplasmsEndometriosis2 more

The purpose of this study is to evaluate the safety and effectiveness of acupuncture in treating women's health conditions.

Completed13 enrollment criteria

Comparative Study of Endometrial Polypectomy Performed With Bipolar Electrode Versapoint and Laser...

Endometrial Polyps

Hysteroscopy today is considered the gold standard for the diagnosis and treatment of endometrial polyps. In recent years we have used the bipolar energy for resection of polyps by hysteroscopy, becoming a routine clinical practice and universally accepted. Resection of endometrial polyps laser energy has recently begun to be used with satisfactory results, so studies are needed to analyze these results and compare it with the usual techniques . This time in advance of medicine, it is appropriate to introduce minimally invasive procedures , allowing resection of endometrial polyps on an outpatient basis without anesthesia and acceptable to most patients. These procedures assume a lower cost and are associated with a lower surgical risk due to their realization without anesthesia . Hypothesis: Resection of polyps outpatient laser diode has a similar or superior to that of the bipolar electrode tolerability. The diode laser is a viable , quick , simple technique with a high percentage of resection and high degree of satisfaction of patients

Completed2 enrollment criteria

Study of D-Methadone in Patients With Chronic Pain

PainBladder Cancer10 more

The purpose of this study is to determine the safest dose of d-methadone that can be given, without causing severe side effects in most patients with chronic pain. Patients are being asked to participate in the Phase I portion of this study.

Completed37 enrollment criteria
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