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Active clinical trials for "Dementia, Vascular"

Results 91-100 of 138

Accurate WiFi-Based Localization of Dementia Patients For Caregiver Support:

DementiaVascular2 more

In this Phase II SBIR project we will enhance a wireless WiFi-based insole that was designed and successfully tested during a Phase I trial with elderly persons with dementia and their caregivers, and then investigate its efficacy in terms of caregiver activity, burden, and quality of life in Phase II. Evaluation will use semi-structured interviews and participant observation data collected from professional and family caregivers of patients with moderate or mild dementia.

Completed16 enrollment criteria

Tailored Music Therapy for Dementia

Alzheimer DementiaDementia4 more

This study evaluates the effect and process of individualized music therapy for home-dwelling persons with mild to moderate dementia. The music therapy is administered individually and includes a close caregiver. Memory of familiar music is found to be retained in persons with dementia. It is assumed to facilitate autobiographical memories and stimulate interaction with significant others. Based on time series analyses we will use statistical process control to evaluate when and how change occur.

Completed14 enrollment criteria

A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831

Mild Cognitive ImpairmentAlzheimer Disease9 more

This study seeks to evaluate the efficacy and safety of NA-83 in subjects with mild cognitive impairment due to Alzheimer's Disease

Completed35 enrollment criteria

The Music, Sleep and Dementia Study

DementiaAlzheimer Disease12 more

The specific aims of this studyare to examine the 1) feasibility; 2) acceptability; and 3) preliminary efficacy of a tailored music intervention in home-dwelling older adults with dementia suffering from sleep disruption. Sixty dyads (older adults with dementia and their caregivers) will be randomized to receive the tailored music intervention immediately or following a four week delay.

Completed13 enrollment criteria

Study of Escitalopram Versus Placebo in the Treatment of Depressive Syndrome in Alzheimer's Disease,...

Depressive Syndrome

The goal of the present study is to compare the effectiveness of the active (S)-enantiomer of citalopram, escitalopram with placebo in the treatment of patients with depressive syndrome complicating Alzheimer's dementia (AD), vascular dementia (VD) or mixed dementia (MD), for 8 weeks of double-blind treatment.

Unknown status25 enrollment criteria

The Clinical Trial of Chinese Herbal Medicine SaiLuoTong Capsule

Vascular Dementia

As a traditional Chinese medicine compound, SaiLuoTong capsule is proven to have beneficial effects on learning and memory ability in animal models of vascular dementia (VaD). The study hypothesis is that SaiLuoTong capsule will be effective in the treatment of patients with VaD and will be well tolerated. The purpose of the study is to determine the efficacy and safety of SaiLuoTong capsule on patients with mild to moderate VaD. The outcome measures include general cognitive function, executive function, daily living skills, and mental behavior changes of symptoms in VaD patients.

Unknown status24 enrollment criteria

Personalized Music Therapy and Agitation in Dementia

Alzheimer's DiseaseVascular Dementia

Symptoms of agitation include abuse or aggressive behaviour toward self or others, appropriate behaviour performed with inappropriate frequency, or behaviours that are inappropriate according to social standards. In the later stages of dementia agitation can contribute significantly to patient distress and caregiver stress, and has been associated with poor quality of life. Previous research studies have shown some evidence that personalized music played in daily care situations reduces agitation. The purpose of this study is to evaluate the effects of personalized music therapy via headphones on agitation during hygiene care (grooming). This study will involve 60 in-patients of the Geriatric Psychiatry ward of Toronto Rehabilitation Institute. The study would take place over the span of 2 weeks and would involve listening to personalized and either non-personalized or no music during daily hygiene care (grooming). Enrolment is completely voluntary and all personal data obtained will remain confidential.

Unknown status9 enrollment criteria

Effect of Zydena (Udenafil) on Cerebral Blood Flow and Peripheral Blood Viscosity

Vascular DementiaSubcortical Vascular Dementia

The purpose of this study is to determine whether Zydena (Udenafil) has effect on cerebral blood flow and peripheral blood viscosity in normal and subcortical vascular cognitive impairment subjects.

Unknown status7 enrollment criteria

Efficacy and Safety of Ferrous Iron on the Prevention of Vascular Cognitive Impairment Among Patients...

Vascular Cognitive ImpairmentDementia4 more

The prevalence of Vascular Cognitive Impairment(VCI) is high in patients after ischemic stroke or transient ischemic attack(TIA) . Effective therapy for the prevention of VCI remains limited. The primary purpose of this study is to evaluate the efficacy and safety of Ferrous iron versus placebo on the prevention of vascular cognitive impairment among patients with ischemic stroke/TIA complicated with Hemoglobin deficiency.

Unknown status19 enrollment criteria

Advanced Cognitive Stimulation Therapy (ACST)

DEMDementia9 more

This study is a feasibility randomised controlled trial (RCT) for an evidence-based intervention for people with moderate to severe dementia. The psychosocial intervention is adapted from Cognitive Stimulation Therapy (CST) and developed within the Medical Research Council (MRC) framework.

Unknown status11 enrollment criteria
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