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Active clinical trials for "Peripheral Vascular Diseases"

Results 1021-1030 of 1034

The SMART-ORACLE Study

Coronary Artery DiseaseStroke4 more

After having had a first cardiovascular event, there is a considerable risk of developing a subsequent event. Only recently, a risk prediction model was developed for this group of patients. Imaging techniques such as the coronary artery calcium score and contrast-enhanced computed tomography (CT) of the coronary and carotid arteries could be able to add improve this model. Imaging may further improve the prediction of future manifestations of arterial disease and personalize disease monitoring and treatment.

Unknown status7 enrollment criteria

Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

Stable AnginaMyocardial Infarction9 more

The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study. CALIBER links patient records from four different data sources: Clinical Practice Research Database (CPRD), MINAP (Myocardial Ischaemia National Audit Project registry) Hospital Episodes Statistics (HES), the Office for National Statistics (ONS).

Unknown status3 enrollment criteria

Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques

AtherosclerosisAortic Aneurysm1 more

Lipid-rich atherosclerotic plaques, or "vulnerable plaques" are prone to rupture, causing local intravascular thrombosis, with subsequent grave clinical consequences. Atherosclerotic plaques normally removed during surgery, and peripheral blood samples will be studied to achieve the following objectives: "1" Define histological features of the vulnerable plaque, analyze its physical characteristics, and investigate selected gene expression. "2" Study biomarkers of inflammation in conjunction with the presence of vulnerable plaques. "3" Explore the potential role of infection in atherogenesis.

Unknown status4 enrollment criteria

The Burden of Peripheral Artery Occlusion Disease and Associated Factors in Peritoneal Dialysis...

Peripheral Vascular Diseases

The investigators want to evaluate the burden of peripheral artery occlusion disease in Taiwan peritoneal dialysis (PD) patients by using ankle-brachial pressure index (ABI) and toe-brachial pressure index (TBI). Furthermore, the investigators hope to demonstrate the possible casual factors of peripheral artery occlusion disease (PAOD) in PD patients.

Unknown status2 enrollment criteria

Micro- and Macrovascular Adaptations in Patients With Peripheral Arterial Disease During Supervised...

PAOD (Peripheral Arterial Obstructive Disease)

Given that previous studies demonstrated the feasibility of the required MRI techniques, we propose to study the macro- and microvascular adaptations in PAOD patients undergoing supervised exercise therapy. It is expected to provide valuable insights into the contribution of each vascular mechanism to the rehabilitation and to identify which vascular mechanism fails or is insufficient for a successful rehabilitation. Improvement of future treatment requires the identification of relevant adaptive mechanisms. With this we will provide early noninvasive MRI readout tools to diagnose and monitor the potential rehabilitation during any form of therapy for PAOD that affects the peripheral vasculature.

Unknown status10 enrollment criteria

Comparison of 3 Ultrasonic Techniques for Measuring the Systolic Pressure Index

Peripheral Arterial DiseaseAtherosclerosis Obliterans2 more

Continuous Doppler ankle brachial index (ABI) is the gold standard for screening and monitoring of peripheral arterial disease (PAD) but is no longer carried out in clinical practice. The recommended measurement was gradually replaced by colour or pulsed Doppler without validation of these techniques. The objective of our study is to compare these two techniques (color Doppler and pulsed Doppler in echodoppler) with respect to the gold standard (continuous Doppler) for ABI measurement.

Unknown status9 enrollment criteria

Validation of the Cheetah NICOM by Comparison to TEE During Open Vascular Surgery - Pilot Study...

Aortic AneurysmPeripheral Arterial Disease

The Cheetah NICOM is a non-invasive cardiac output monitor that has been validated in various clinical contexts but not during the occlusion of major arteries, as takes place in vascular surgery. The present study will evaluate the precision and validity of the measures taken by the device during open vascular surgery procedures. The measurements will be compared to the those calculated by transesophageal echocardiography at various key points during the surgeries. The validity of the cardiac output, stroke volume and stroke volume variation measurements will be evaluated, as well as the device's ability to track rapid changes in cardiac output.

Unknown status8 enrollment criteria

Comparative Physiologic Technology Study

Peripheral Arterial Disease

This study is designed to test two hypotheses: The PADnet+ testing system produces clinically equivalent results as the Parks Flo-Lab testing system in a group of patients referred for evaluation of PAD of the limbs when performed by a Registered Vascular Technologist (RVT). The PADnet+ testing system produces clinically equivalent results when the testing is repeated on the above patients and performed by staff specifically trained on the use of the PADnet+ system but are not vascular technologists nor hold the RVT certification.

Unknown status2 enrollment criteria

Foot Perfusion Analysis to Predict Limb Salvage

Critical Limb IschemiaPeripheral Arterial Disease

This study aims at evaluating the correlation between foot perfusion on angiographies performed before and after revascularization and limb salvage in patients with critical limb ischemia.

Unknown status5 enrollment criteria

Evaluation of Muscle Ischemia in Arterial Claudication (Tsingtao)

Peripheral Arterial Disease

The goal is to compare the results observed in patients that had both an exercise oximetry and a thallium scintigraphy for lower limb claudication

Unknown status2 enrollment criteria
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