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Active clinical trials for "Peripheral Vascular Diseases"

Results 891-900 of 1034

Iloprost Therapy in Patients With Critical Limb Ischemia

Peripheral Arterial Disease

Monitoring efficacy and safety aspects of iv. iloprost therapy of patients with critical limb ischemia by recording clinical parameters.

Completed4 enrollment criteria

Magnetic Resonance Angiography for Peripheral Arterial Disease (PAD)

Peripheral Arterial Disease (PAD)

The purpose of this study is to compare the difference between two magnetic resonance imaging (MRI) techniques for visualizing arteries. The study hypothesizes that one method that relies upon imaging flowing blood in the pelvic and leg arteries will not be as accurate or efficient as injecting a safe imaging agent to change the appearance of the blood on the MRI. Both methods will be compared with Digital Subtraction Angiography (DSA).

Unknown status6 enrollment criteria

Magnetic Resonance Imaging to Identify Characteristics of Plaque Build-Up in People With Peripheral...

Peripheral Vascular Diseases

Peripheral arterial disease (PAD) is a disease in which fatty build-up, or "plaque," accumulates in the peripheral arteries. People with PAD often experience leg pain while walking due to reduced blood flow to the legs. This study will use magnetic resonance imaging (MRI) techniques to examine how specific features of plaque build-up in the leg arteries affect walking ability, leg strength, and balance in people with PAD.

Completed13 enrollment criteria

Arterial Imaging of Inflammation and Resolution After Endovascular Surgery

Peripheral Arterial DiseaseClaudication6 more

This study evaluates the local inflammatory and resolution response of patients undergoing peripheral vascular intervention like an angioplasty of the superficial femoral artery (SFA) or popliteal artery, or stenting of the iliac artery or SFA, through the use of Positron emission tomography-magnetic resonance imaging (PET/MRI). PET/MRI will be performed prior to intervention, one day and one week after intervention.

Completed13 enrollment criteria

SOLARIS Endoprosthesis in Iliac Occlusive Disease

Peripheral Arterial Disease

Fifty patients will be treated with Solaris Endoprosthesis and followed up to 2 years with Walking Impairment Questionnaire and Doppler Ultrasound evaluation in 30 days, 6 months and 12 months.

Completed15 enrollment criteria

Aortoiliac Stenosis in Kidney Transplantation

Aorto-Iliac Arterial StenosisPeripheral Arterial Disease1 more

The impact of aortoiliac stenosis on kidney transplant patients remains unclear. This study aims to investigate the safety and efficacy of kidney transplantation in patients with aortoiliac stenosis.

Completed4 enrollment criteria

PMCF Study for Peripheral Arteries Above the Knee (ATK)

Peripheral Arterial DiseaseFemoropopliteal Stenosis2 more

The rationale of this study is to confirm and support the clinical safety and performance of the products in a real-word population of 350 patients who underwent an endovascular intervention within standard-of-care (SOC) of the ilio-femoropopliteal artery, using at least 1 of the products (named above) from Cordis US Corp.

Completed8 enrollment criteria

GORE® VIABAHN® Endoprosthesis Post-Marketing Surveillance Study (JPS 16-03)

Peripheral Arterial Disease

This study will confirm device efficacy and safety in the clinical setting after the launch of the GORE® VIABAHN® Endoprosthesis for the treatment of symptomatic peripheral arterial disease in the superficial femoral arteries.

Completed1 enrollment criteria

Real-World Safety Analysis of Paclitaxel Devices Used for the Treatment of Peripheral Arterial Disease...

Peripheral Arterial Disease

Treatment with paclitaxel-based endovascular devices (PED) has become a common treatment option for patients with peripheral artery disease (PAD) involving the femoral-popliteal artery. However, an aggregate level meta-analysis identified an association between the use of PED and increased all-cause mortality at both two and five-year follow-up intervals, though there are significant limitations of these analyses. Exploration of real-world data has been suggested as a means to further investigate the safety of PED. The current study explores the association of PED and mortality in real-world data using U.S. commercial claims from the FAIR Health data warehouse.

Completed6 enrollment criteria

DISRUPT PAD III Observational Study

Peripheral Arterial Disease

The Disrupt PAD III study was designed as a randomized controlled trial (RCT) with an additional observational registry component. The registry, referred to as the Disrupt PAD III Observational Study (PAD III OS), was a global, prospective, multi-center, single-arm registry of the Shockwave Peripheral Intravascular Lithotripsy (IVL) System. The objective of this study was to assess the real-world acute performance of IVL in the treatment of calcified, stenotic, peripheral arteries that may not qualify for inclusion in the RCT. The study was designed to enroll a maximum of 1500 subjects from up to 60 global sites with a minimum of 200 subjects treated with the S4 IVL catheter, a line extension designed to treat smaller diameter peripheral vessels, including calcified below-the-knee (BTK) lesions. Subjects were required to have target lesions in the iliac, femoral, ilio-femoral, popliteal, or infra-popliteal arteries with at least moderate calcification as determined by the investigator, defined as calcification within the lesion on both sides of the vessel assessed by angiography. Adjunctive therapies such as atherectomy, specialty balloons, and stents were allowed. Subjects were followed through discharge.

Completed9 enrollment criteria
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