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Active clinical trials for "Vasculitis"

Results 61-70 of 211

VCRC Tissue Repository

AortitisCutaneous Vasculitis9 more

The purpose of this study is to collect existing tissue specimens from subjects enrolled in Vasculitis Clinical Research Consortium (VCRC) studies. Analysis of these tissue specimens and linked clinical data collected through VCRC studies may lead to the identification and development of a series of translational research projects. Results of these studies will provide vasculitis researchers with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.

Recruiting3 enrollment criteria

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

Cryoglobulinemic Vasculitis (CV)Drug-induced Vasculitis8 more

Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.

Recruiting19 enrollment criteria

Avacostar - (PASS)

ANCA-associated Vasculitis

The Avacostar PASS is a non-interventional, multi-national, prospective cohort study that will collect data from 2 cohorts of patients: those treated with avacopan for active severe AAV, and a second cohort treated with a cyclophosphamide or rituximab-based induction regimen without avacopan for active severe AAV. The overall study duration is anticipated to be up to 7 years, including a recruitment period of approximately 3 years.

Recruiting6 enrollment criteria

A Single-Site Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed...

Age-Related Macular DegenerationAllergies45 more

To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and preventative methods for specific and complex conditions.

Recruiting8 enrollment criteria

Longitudinal Study for Central Nervous System Vasculitis

Central Nervous System VasculitisCNS Vasculitis2 more

Primary central nervous system vasculitis (CNSV) is a potentially fatal, single-organ vasculitis that often involves a spectrum of neurologic complications, including strokes, cognitive and speech impairment, visual loss, dementia, and encephalopathy. The purpose of this study is to establish a research cohort to investigate the disease process, treatments, and patient outcomes in CNSV.

Recruiting6 enrollment criteria

A Real World, Observational Registry of Chronic Wounds and Ulcers

Diabetic FootVaricose Ulcer13 more

More than 100 hospital based outpatient wound centers in the USA and Puerto Rico agree to transmit structured data on all patients followed with chronic wounds and ulcers (e.g. diabetic foot ulcers, venous ulcers, pressure ulcers, arterial ulcers, surgical wounds, and traumatic wounds). Data are collected at point of care including adherence to wound care quality measures developed by the USWR as a Qualified Clinical Data Registry (QCDR).

Recruiting1 enrollment criteria

Longitudinal Imaging in Patients With Large Vessel Vasculitis to Predict Further Disease Course...

Giant Cell ArteritisLarge Vessel Giant Cell Arteriitis

Longitudinal imaging in patients with large vessel vasculitis to predict further disease course

Recruiting7 enrollment criteria

Prospective Longitudinal Cohort Study of Vasculitis Patients

Vasculitis

VASCO is a prospective observational cohort study which aim to describe the presentation, comorbidities, management, outcomes and damage of vasculitis patients, from the analysis of the clinical, biological and immunological data.

Recruiting14 enrollment criteria

FDG Digital PET/CT as First Line Investigation for Giant Cell Arteritis

Giant Cell ArteritisVasculitis

Giant cell arteritis (GCA) causes inflammation of the arteries and can lead to serious complications such as blindness, necessitating rapid diagnosis and treatment. Although older technology non-digital PET/CT scans are routinely used for the diagnosis of GCA in large arteries, they have not been able to reliably detect inflammation of the small arteries responsible for blindness. Recent technological advances have enabled PET/CT imaging of millimetric disease in the body, and Quebec has been one of the first to deploy these new digital PET/CT scanners, which are now able to resolve small arteries. In the proposed research study, patients who are suspected by their doctors to have GCA will undergo temporal artery biopsy (the standard of care), an ultrasound of the temporal arteries, and digital PET/CT scan after injection of radioactive glucose. Digital PET/CT scans will be interpreted for the presence of abnormal uptake in the large and small arteries, as well as for the presence of other causes of the patient's symptoms. The diagnostic accuracy of PET/CT and ultrasound will be evaluated with respect to an expert panel diagnosis of giant cell arteritis and compared. Results will be adjusted for lack of a perfect reference test using advanced statistics. The goal will be to see if digital PET/CT can become a single, integrated test to diagnose this disease.

Recruiting8 enrollment criteria

Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases...

Lupus ErythematosusScleroderma3 more

The aim of this project is to start a biological and clinical collection of patients presenting systemic autoimmune disease. This collection will provide appropriate biological samples to identify new biomarkers and to be accessible to the medical, scientific and industrial communities for the identification of new therapeutic strategies

Recruiting6 enrollment criteria
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