Aspirin for Venous Ulcers: Randomised Trial (AVURT)
Venous Leg UlcerThis efficacy study evaluates the safety and effectiveness of aspirin for venous leg ulcer healing. The study also examines whether patients can be recruited to a larger study. Patients with chronic venous leg ulceration presenting and undergoing care in leg ulcer community clinics or hospital out-patient clinics, or registered with a clinic but are receiving care at home will be recruited. All patients will receive standard compression bandaging. Half of the participants will be randomised to receive aspirin, while the other half will receive a placebo.
Efficacy Study of the Application of Low Level Laser Light to Treat Venous Stasis Ulcers
Venous Stasis UlcerThe purpose of this study is to determine whether low level laser light therapy is effective as an adjunctive therapy to the healing of venous stasis leg ulcers.
Restore Calcium Alginate Dressing, Silver vs Aquacel Ag in the Treatment of Critically Colonized...
Venous UlcerInfectionCalcium alginate dressings with silver have been found to be safe and effective for use for leg ulcers. The primary objective is to compare Restore Calcium Alginate Dressing, Silver to AqualCel Ag Dressing on the following parameters: No further progression toward infection (bioburden), ease of application and removal, and percent progression to closure. The secondary objective is to obtain photographic documentation of the leg ulcers during the course of the study.
Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers
Venous UlcersThe purpose of this study is to determine whether nitric oxide (NO)gas is effective in the treatment of venous ulcers of the lower leg.
Debritom - Micro Water Jet Technology and Wound Healing
Diabetic Foot UlcerNon-healing Wound3 moreThis study will investigate the clinical efficacy of micro water jet technology in the debridement and healing of chronic lower extremity ulcers.
Randomized Clinical Trial of Pneumatic Compression Device for the Treatment of Venous Ulcers and...
LymphedemaThe purpose of this study is to evaluate the effect of pneumatic compression in improving symptoms, quality of life and wound healing in patients with venous ulcers and/or lymphedema.
Flexitouch Compression System for Venous Stasis Ulcer
Venous Stasis UlcerThe researchers hypothesize that utilization of the Flexitouch system will improve the healing rates of (venous stasis ulcers) VSU compared to traditional compression wrapping therapy alone. Primary Objective: The primary study objective is to determine whether the complete healing rate of venous stasis ulcers at 12 weeks is improved by the addition of Flexitouch® System compression therapy to a standard regimen of compression wrapping. Secondary Objectives: To determine whether the addition of Flexitouch System compression therapy to a standard regimen of compression wrapping increases the percentage reduction in wound surface area. To determine whether the addition of Flexitouch compression therapy to a standard regimen of compression wrapping increases the percentage reduction in volume of the affected limb. To determine whether the addition of Flexitouch compression therapy to a standard regimen of compression wrapping decreases the time to healing of the venous stasis ulcer.
PluroGel on Wounds of Mixed Etiology
Venous UlcerArterial UlcerA randomized controlled study (RCT) to investigate the topical effectiveness of PluroGel in healing venous and mixed aetiology leg ulcers. Patients with venous and mixed aetiology leg ulcers will be identified from hospital outpatient clinics. Willing patients meeting the inclusion and exclusion criteria will be consented and assessed in line with standard care. Participants will be randomized at Week 2 to receive either topical PluroGel or Intrasite gel (an alternative topical hydrogel product) if inclusion criteria is met.
Effectiveness of Sorbion in the Treatment of Venous Leg Ulcers The Protocol Elements
Venous Wound UlcersTo follow the effectiveness of Sorbion Dressing in the treatment of highly exuding venous leg ulcers.
Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers
Venous UlcersThis study will test the safety and efficacy of nitric oxide gas in the treatment of venous leg ulcers