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Active clinical trials for "Tachycardia, Ventricular"

Results 191-200 of 351

VIVO™ Accuracy Study

Premature Ventricular ContractionVentricular Tachycardia

A multi-center study designed to assess the accuracy of VIVO™ in determining the location of a PVC/VT foci in comparison to an electroanatomical mapping system.

Completed11 enrollment criteria

Stereotactic Non-invasive Ablation of Ventricular Tachycardia

Ventricular Tachycardia

STereotactic Ablative Radiosurgery of recurrent Ventricular Tachycardia in structural heart disease (STAR-VT).

Withdrawn14 enrollment criteria

Noninvasive Cardiac Radioablation for Ventricular Tachycardia Refractory to Medication and Catheter...

Ventricular Tachycardia

The purpose of this study is to evaluate the safety and efficacy of cardiac radioablation (CRA) as a means of noninvasive treatment of ventricular tachycardia (VT) refractory to both medication and catheter ablation.

Withdrawn22 enrollment criteria

Comparison of Ventricular Tachycardia Ablation Strategies in Patients With Ischemic Cardiomyopathy...

Ventricular Tachycardia

This is a prospective multicenter randomized open-label study aiming to assess whether endocardial or endocardial-epicardial ablation is superior to the standard approach (i.e., Antiarrhythmic drugs) in achievement of long-term ventricular tachycardia (VT) treatment success.

Withdrawn19 enrollment criteria

DATAS: The Dual Chamber & Atrial Tachyarrhythmias Adverse Events Study

Ventricular TachycardiaVentricular Fibrillation2 more

The Dual Chamber & Atrial Tachyarrhythmias Adverse Events Study (DATAS) was designed to analyze the ability of dual chamber ICDs, to reduce clinically significant adverse events as compared to single chamber ICD in a non selected population with conventional indication of ICD implantation.

Completed11 enrollment criteria

Utility and Procedural Feasibility of REBOA Operationalized for Non-Trauma Application (UP-FRONT)...

Cardiac ArrestOut-Of-Hospital2 more

Single center randomized-controlled trial in out-of-hospital cardiac arrest (OHCA) patients. This study will investigate the feasibility and utility of the Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) procedure using a REBOA catheter device in patients who have experienced an OHCA and have not regained return of spontaneous circulation (ROSC).

Withdrawn12 enrollment criteria

PAtient NOtifier Feature for Reduction of Anxiety

TachycardiaVentricular

This study is intended to look at the effect of the SJM vibrating Patient Notifier™ system, which will warn the patient of possible failures of the implanted system, on reducing patient device related anxiety

Completed12 enrollment criteria

PREPARE - Primary Prevention Parameters Evaluation

TachycardiaVentricular4 more

The purpose of this study is to test specific device programming in patients without a previous history of a life-threatening, abnormally fast heartbeat who are implanted with a Medtronic ICD (Implantable Cardioconverter Defibrillator) or ICD with CRT (Cardiac Resynchronozation Therapy) device. The information learned from this study could be used to guide physicians in future ICD or CRT device programming.

Completed3 enrollment criteria

Percutaneous Inferior Cervical Sympathetic Block for Treatment of Refractory Ventricular Tachycardia...

Ventricular Tachycardia

The purpose of this research study is to examine the effect of percutaneous inferior cervical sympathetic block on life threatening abnormal heart rhythms called ventricular tachycardia or ventricular fibrillation that can lead to sudden cardiac death.

Withdrawn16 enrollment criteria

Clonidine to Prevent Implantable Cardiovertor Defibrillator Firing

Ventricular Tachycardia

Cardiac arrest or sustained VT (ventricular tachycardia) in patients with heart disease is best treated with an ICD (implantable cardioverter defibrillator). However, the ICD alone is not appropriate therapy for patients with frequent VT episodes. In fact frequent shocks for VT may predict a poorer prognosis. Anti-arrhythmic drugs are co-administered with ICDs in up to 50% of patients to prevent VT episodes, but antiarrhythmic drugs may have harmful effects. Thus improved drugs to prevent VT without interfering with ICD function are needed. Recent data including our own suggest that clonidine may be a new therapy to prevent ICD shocks. It may act centrally on sympathetic outflow and peripherally and selectively on cardiac Purkinje, to suppress and control VT occurring in patients. Our purpose is to test the hypothesis that clonidine reduces frequent VT better than beta blocker in patients with ICDs. After informed consent patients will be randomized in a single blind fashion to either clonidine or metoprolol given three times per day. Other prescribed drugs may be adjusted to promote toleration of the study drug. ICD interrogations of episodes of VT will be the primary endpoint. Device based NIPS (non-invasive programmed stimulation) testing in a subset of these patients will allow mechanistic understanding of the clonidine effect. All of the procedural techniques are in place as performed clinically; preliminary data are given showing feasibility of the project.

Withdrawn5 enrollment criteria
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