PET Imaging of Chronic Pain Syndromes
Chronic Pain SyndromeCentral nervous system (CNS) changes associated with pain have been difficult to measure until the development of functional neuroimaging techniques such as positron emission tomography (PET). We have previously observed asymmetry in the thalamus associated with chronic pain that altered during acupuncture therapy. Imaging studies of therapeutic techniques for chronic pain in animals and humans have been quite limited. This study will be the first to utilize FDG PET-MRI imaging of both the brain and body in order to assess CNS changes and peripheral body changes related to chronic pain and its potential management.
Median Nerve Hydro-dissection Using Single Injection of Hyalase as a Novel Treatment of Carpal Tunnel...
Carpal Tunnel SyndromePain1 moreCarpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline of the median nerve could offer symptoms and clinical improvement
Blood Flow - an Underlying Mechanism Behind Clinical Improvements in Patients With Subacromial Pain...
Chronic PainThe purpose of this randomized clinical trial is two-fold. Firstly to see if patients suffering Subacromial Pain Syndrome can improve blood flow in the supraspinatus muscle in their shoulder, and secondly to investigate how changes in this blood flow are related to pain experience and shoulder function.
Effectiveness of the Precision Spinal Cord Stimulator System at Sub-Perception Amplitude
Chronic PainTo demonstrate sustained clinically significant pain relief in patients with chronic pain when using the Boston Scientific Precision Spinal Cord Stimulator (SCS) System at sub-perception amplitude
Randomized Study of Failed SCS Trials Comparing Outcomes Using the Observational Mechanical Gateway...
Chronic PainThe purpose of this study is to evaluate patient preference of the Boston Scientific Corporation (BSC) commercially approved spinal cord stimulation (SCS) systems with the Observational Mechanical Gateway (OMG) in patients who failed non-BSC SCS trial therapy.
Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
Joint DiseasePain3 morePost-discharge pain after total knee arthroplasty remains problematic; many patients have excessive pain at the 2 week time point (and often thereafter). Reduction in opioid use has become a national goal, due to the 'epidemic' in opioid misuse. In addition to enrolling non-opioid users, we will enroll up to 15 chronic opioid users.
Study Evaluating the Impact of Mesh Pore Size on Chronic Pain After Lichtenstein Hernioplasty
Inguinal HerniaThe aim of the present study is to determine whether usage of mesh with larger pores, compared with mesh with smaller pores, would result in decreased rate of chronic pain after open inguinal hernia repair.
Guided Internet-delivered Acceptance and Commitment Therapy for Chronic Pain Patients
Chronic PainThe aim of this study was to investigate if guided internet-delivered acceptance and commitment therapy (ACT)would help chronic pain patients.
Use of Xtampza ER to Overcome Difficulties in Swallowing Opioid Pills
Chronic PainOpioid Use1 moreThis study will examine how the use of Xtampza ER, an opioid analgesic packaged in openable microsphere-containing capsules, affects swallowing satisfaction, pain, and physical and mental health outcomes in chronic pain patients.
Peri-procedural Smoking Cessation Program in Patients With Chronic Pain
Chronic PainSmokingThis single arm study will assess whether smoking cessation counseling offered to chronic pain patients is effective in reducing pain and cigarette use.