All clinical trials

The aim of the study is to examine the reliability of the method by applying the Functional Gait Assessment in patients with Multiple Sclerosis via online video conferencing. For this purpose, walking of each patient to be included in the study; The evaluation results will be compared and the intra-rater reliability will be investigated by evaluating both face-to-face and online video conferencing methods. Since the Functional Gait Assessment is not available in Turkish, the scale will also be validated by adapting it to Turkish within the scope of the study.

The upper extremity in people with Multiple Sclerosis (pwMS) has become a more popular research topic in recent years, with the increase in studies reporting widespread involvement. The aim of our study was to evaluate the upper extremity from multiple perspectives in early stage pwMS, to identify problems by comparing them with healthy individuals, and to examine the relationship of problems with activity and participation.

Scabies is a Neglected Tropical Disease, particularly important in autochthonous populations. Treatment failures could explain the high prevalence of this disease in Amerindian and Maroon populations of French Guiana. Our main objective is to look for specific sociodemographic risk factors for treatment failure of scabies in the remote areas of French Guiana. A secondary objective is to evaluate the prevalence of scabies and its complications.

From July to September 2020, in a first uncontrolled cohort study, 478 patients who were hospitalized at Bicêtre hospital for COVID-19 and who survived were evaluated at 4 months (publication accepted at JAMA). The current project aims to bring together the means to continue this work during the 2nd epidemic wave.

To explore the genotype-phenotype correlation of SLC26A4 mutations in cochlear-implanted patients with enlarged vestibular aqueduct.

Research Hypothesis: Lisfranc tarsometatarsal joint arthrodesis is a reliable surgical procedure, allowing the restoration of satisfactory function and a painless foot with an acceptable complication rate. Objective of the study: To analyze the clinical and radiographic results in the medium term of arthrodesis of the Lisfranc tarsometatarsal joint in cases of primary osteoarthritis, post-traumatic osteoarthritis or in cases of inflammatory pathology.

Growth changes occur from the intrauterine life to senility, hard tissues like bones and teeth undergo changes with growth, a change in shape and/or fusion of ossification centers, the stability of these changes facilitate ease in estimation of age from hard tissue samples ( Bhalaji ,2006;Reddy,2006; Mohite et al.,2011). Mandibles were used for the study for two simple causes: First, there appears to be a lack of standards utilizing this element and second, this bone is often recovered mostly intact (Franklin et al.,2008) The mandible is considered the most durable facial bone ;is due to the presence of a dense layer of compact bone and therefore remains well conserved than many other bones and the only movable bone of the skull available for gender identification; is due to the morphological characteristics of mandible, and radiology plays an important role in it. It is composed of two hemi mandibles united at the midline by a vertical symphysis. Each one of them is composed of a horizontal body with a posterior vertical extension termed the ramus(ndira et al.,2012 ). Mandibular canines are found to exhibit the highest sexual dimorphism.The mean age of eruption of mandibular canines is 10.87 years, and they are the last teeth to be extracted with respect to age; so, they can be considered as the key teeth for personal identification (Khangura et al.,2011; Padmavati et al.,2011; Yuwanati et al.,2012). Measurements of the mandibular ramus tend to show higher sexual dimorphism, and variations between the sexes are mostly more marked in the mandibular ramus than in the mandibular body (Humphrey et al.,1999). Gonial angle is commonly used to determine the rotation of the mandible and to identify growth pattern, it is a common parameter used to describe orthodontic extractions or surgical treatments(Kitai et al.,2013). Several studies focused on the comparison between CBCT (Cone Beam Computed Tomography) and OPG (Orthopantomograph) for visualization of bone and teeth (Dalessandri et al.,2012 ;Savoldi et al.,2015). OPG is a very popular technique ,the most available and commonly used extra-oral radiography, its lower cost ,wide area coverage ,ease of preparation have made it an excellent choice for routine examination of many structures thus useful for research purpose does not involve the patient any additional exposure or cost(Ghosh et al.,2009 ;Sairam et al.,2016). The CBCT imaging device can obtain undistorted three-dimensional (3D) images of good quality with a low radiation dose (Yamamoto et al.,2003).

The aim of our study is primarily to evaluate the professional practices over the last years in the pediatric emergencies of the Nancy's Hospital for the BATiC. This, in order to identify the traumatic mechanisms and the initial clinical elements which would make it possible to detect the patients at low risk of developing visceral lesions. Then, a management could be proposed which would rationalize the use of additional examinations and would favor the monitoring and the clinical reassessment after the initial management of a minor trauma. The study of the data will then aim to establish a composite score (anamnestic and clinical) of initial evaluation, from which could result a uniform management protocol (clinical, biological and imaging) of the minor BATiC, of the intermediate BATiC and the major BATiC, applicable to pediatric emergencies at the Nancy's Hospital.

The DISENGAGE@rest study is a prospective registry carried out at Federico II University of Naples with the aim to evaluate the influence of the guiding catheter engagement within the coronary ostium on both FFR and non-hyperaemic pressure ratios values (such as Pd/Pa and the Resting Full-cycle Ratio -RFR), as well as the corresponding clinical impact on decision-making strategies. Consecutive patients with at least one intermediate stenosis (40%-90% by visual estimation) in any of the 3 main coronary arteries will be included.

The purpose of this study is to collect perioperative diagnosis and treatment information for cardiac surgery patients, collect blood samples for laboratory testing when necessary, and analyze the data to clarify the risk factors of pulmonary complications in patients undergoing cardiac surgery during the perioperative period. On this basis, a clinical early warning model for pulmonary complications after cardiac surgery will be developed to reduce the risk of pulmonary complications and even death in clinical practice.