search
Back to results

Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures

Primary Purpose

Peripheral Vascular Diseases, Arterial Occlusive Diseases, Ischemia

Status
Completed
Phase
Phase 2
Locations
International
Study Type
Interventional
Intervention
CGT003 (E2F Duplex Decoy)
Sponsored by
Anesiva, Inc.
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional prevention trial for Peripheral Vascular Diseases focused on measuring atherosclerotic vascular disease, chronic critical limb ischemia, neointimal hyperplasia, peripheral vein bypass, infra-inguinal bypass grafting surgery, graft stenosis, occluded grafts

Eligibility Criteria

18 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

PATIENTS MUST: Be scheduled to undergo infra-inguinal bypass grafting surgery using excised autogenous vein for Chronic Critical Limb Ischemia (i.e., rest pain, non-healing ulceration or gangrene). For patients presenting with rest pain as the only manifestation of CCLI, must have the diagnosis confirmed by at least one of the following,: i.) an ankle pressure of < 50 mmHg (or ABI <0.4), ii.) a toe pressure < 30 mmHg, iii.) a reduced TCPO2 < 30 mmHg, or iv.) a severely ischemic or flat line transtarsal pulse volume recording (i.e., Category V). Be males or females of at least 18 years old. Have agreed to participate voluntarily and signed and dated an IRB-approved, Patient Informed Consent form. Have a documented negative serum pregnancy test for all women of childbearing potential. Be using an acceptable method of birth control if of reproductive potential. Note: Patients undergoing operations to replace previously occluded grafts that involve placement of an entirely new bypass graft ARE eligible for this study.

Sites / Locations

  • The Kirklin Clinic
  • University Hospital
  • Mobile Infirmary Medical Center
  • Vascular Specialists of Mobile, PC
  • Springhill Memorial Hopsital
  • Tucson Heart Hospital
  • University Medical Center
  • Northwest Hospital
  • Tucson Vascular Surgery
  • Southern Arizona Vascular Institute
  • St. Mary's Hospital
  • Baptist Health
  • Central Arkansas Veterans Healthcare System
  • University of Arkansas for Medical Sciences Hospital
  • Cedars-Sinai Medical Center
  • VA Palo Alto Health Care System
  • Kaiser Permanente - San Diego, SCPMG, Department of Surgery
  • Kaiser Permanente Franklin Medical Center
  • Exempla Healthcare Saint Joseph Hospital
  • Hartford Hospital
  • Washington Hospital Center, Center for Vascular Care
  • Malcom Randall VA Medical Center
  • Shands Hospital at the University of Florida
  • Samson Showalter Vascular Specialists
  • Clinical Research Center
  • Sarasota Memorial Hospital
  • Vascular & Surgery Assoc.
  • Tampa General Hospital
  • Emory University School of Medicine Hospital
  • Saint Joseph's Hospital of Atlanta
  • Vascular Institute of Georgia
  • Atlanta VA Medical Center
  • Northwestern Memorial Hospital
  • University of Chicago
  • Methodist Hospital
  • Veteran's Affairs Medical Center
  • Our Lady of the Lake Regional Medical Center
  • Maine Medical Center
  • University of Maryland Hospital
  • Johns Hopkins Hospital
  • New England Medical Center Hospital
  • Brigham & Women's Hospital
  • Beth-Israel Deaconess Medical Center
  • Dept. of Surgery at Harvard Medical Faculty Physicians
  • William Beaumont Hospital
  • O.W. Brown, M.D.
  • Lakeland Hospital
  • Steven D. Rimar, M.D.
  • St. Mary's Hospital
  • Mayo Clinic
  • Washington University School of Medicine
  • Methodist Hospital
  • Dartmouth Hitchcock Medical Center
  • Dr. Randy Shafrtiz, Clinical Office
  • Morristown Memorial Hospital
  • Surgical Specialists of NJ, Morris Vascular Center
  • Robert Wood Johnson University Hospital
  • Umdnj-Rwjms
  • UMDNJ - New Jersey Medical School, University Hospital
  • Albany Medical Center
  • Montefiore Hospital
  • Kings County Hospital
  • SUNY Downstate University Hospital of Brooklyn and Medical School
  • Maimonides Medical Center
  • New York Presbyterian Hospital, Weill Medical College of Cornell University
  • Mount Sinai Medical Center
  • Columbia Presbyterian Medical Center
  • University of Rochester Medical Center
  • Gaston Memorial Hospital
  • Pitt County Memorial Hospital
  • Department of Surgery, Division of Vascular Surgery, East Carolina University
  • Wake Forest University School of Medicine
  • Cleveland Clinic Foundation
  • Flower Hospital
  • Jobst Vascular Center
  • The Toledo Hospital
  • Oregon Health Sciences University
  • Penn State College of Medicine
  • Hospital of the University of Pennsylvania
  • Temple University Hospital
  • Veterans Administration Healthcare System
  • Robert Packer Hospital
  • Rhode Island Hospital
  • Medical University of South Carolina Hospital
  • University of Tennessee Medical Center
  • St. Thomas Medical
  • The Surgical Group, PLLC
  • Baylor College of Medicine
  • VAMC
  • University Medical Center
  • Texas Tech University Health Sciences Center
  • Baptist Medical Center
  • Peripheral Vascular Associates
  • Northeast Baptist Hospital
  • Peripheral Vascular Associates
  • Pro-Research Group
  • Southwest Texas Methodist Hospital
  • University of Utah Hospital and Clinics
  • Vascular and Transplant Specialists, Peripheral Vascular Laboratory
  • Vascular and Transplant Specialsts, Peripheral and Vascular Laboratory
  • Southampton Memorial Hospital
  • Shore Memorial Hospital
  • Chesapeake General Hospital
  • Vascular and Transplant Specialists, Peripheral Vascular Laboratory
  • Virginia Vascular Associates
  • Sentara Norfolk General Hospital
  • Vascular and Transplant Specialists, Peripheral Vascular Laboratory
  • Carilion Roanoke Community Hospital
  • Carilion Roanoke Memorial Hospital
  • Jefferson Surgical Clinic
  • Harborview Medical Center
  • VA Puget Sound Health Care System
  • University of Washington Medical Center
  • Froedert Memorial Lutheran Hospital
  • Medical College of Wisconsin
  • Clement J. Zablocki VAMC
  • Peter Lougheed Centre
  • Vancouver Hospital & Health Sciences Centre
  • St. Boniface General Hospital
  • London Health Sciences Centre
  • Ottawa Hospital
  • University Health Network
  • St. Paul's Hospital

Outcomes

Primary Outcome Measures

Secondary Outcome Measures

Full Information

First Posted
July 18, 2002
Last Updated
July 14, 2005
Sponsor
Anesiva, Inc.
search

1. Study Identification

Unique Protocol Identification Number
NCT00041925
Brief Title
Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures
Official Title
A Phase III, Multi-Center Randomized, Double-Blind, Placebo-Controlled Trial of the Ex Vivo Treatment With CGT003 of Peripheral Vein Grafts in Patients Undergoing Peripheral Arterial Bypass Graft Procedures
Study Type
Interventional

2. Study Status

Record Verification Date
July 2005
Overall Recruitment Status
Completed
Study Start Date
November 2001 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
November 2004 (undefined)

3. Sponsor/Collaborators

Name of the Sponsor
Anesiva, Inc.

4. Oversight

5. Study Description

Brief Summary
The purpose of this study is to determine the efficacy of graft pretreatment with the E2F decoy, CGT003, as compared to placebo, on the occurrence of graft failure among patients who receive autogenous vein grafts to treat chronic critical limb ischemia; on the occurrence of clinically significant graft stenosis (more than or equal to 70%); and on the incidence of critical limb ischemia (e.g., gangrene, non-healing ischemic ulcers or ischemic rest pain).
Detailed Description
Peripheral vascular disease manifested by narrowing of the peripheral arteries is one of the more common manifestations of atherosclerotic vascular disease. Complications such as claudication, rest pain, and impaired wound healing are frequent and may result in gangrene and amputation. Restoration of circulation to the lower extremities may be undertaken using a variety of techniques including angioplasty, stenting, and bypass grafting. Approximately 99,000 infra-inguinal bypass procedures were performed in the U.S. in 1998. It is estimated that approximately 22% of all infra-inguinal bypass grafts will fail by 12 months. Graft failure rates have been estimated to increase to 40% at 12 months for patients receiving composite, cephalic or lesser saphenous (high-risk) vein grafts (Vascular Surgery Registry, Brigham and Women's Hospital). These primary graft failures are typically due to stenoses that result from neointimal hyperplasia, a pathological adaptation process that occurs in veins exposed to the arterial circulation. The consequences of graft failure are as significant as those of primary atherosclerotic disease and include ischemia and poor wound healing that may result in amputation. Since the long-term patency of venous grafts can be improved with treatment prior to frank occlusion, considerable efforts have been focused on the methods for the detection of grafts at high-risk for failure. Duplex ultrasonography has been determined to be a sensitive screening test for the early detection of failing grafts. Peak systolic velocity (PSV), as measured by duplex ultrasound, has been shown to be a sensitive marker for low flow, and wave form analysis has permitted the identification of areas of stenosis in the vein under study. Management of patients who have undergone infra-inguinal bypass therefore includes routine surveillance with duplex ultrasound and the immediate correction of significant (more than or equal to 70%) graft stenoses.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Peripheral Vascular Diseases, Arterial Occlusive Diseases, Ischemia, Graft Occlusion, Vascular, Hyperplasia
Keywords
atherosclerotic vascular disease, chronic critical limb ischemia, neointimal hyperplasia, peripheral vein bypass, infra-inguinal bypass grafting surgery, graft stenosis, occluded grafts

7. Study Design

Primary Purpose
Prevention
Study Phase
Phase 2, Phase 3
Interventional Study Model
Single Group Assignment
Masking
Double
Allocation
Randomized
Enrollment
1400 (false)

8. Arms, Groups, and Interventions

Intervention Type
Drug
Intervention Name(s)
CGT003 (E2F Duplex Decoy)

10. Eligibility

Sex
All
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
PATIENTS MUST: Be scheduled to undergo infra-inguinal bypass grafting surgery using excised autogenous vein for Chronic Critical Limb Ischemia (i.e., rest pain, non-healing ulceration or gangrene). For patients presenting with rest pain as the only manifestation of CCLI, must have the diagnosis confirmed by at least one of the following,: i.) an ankle pressure of < 50 mmHg (or ABI <0.4), ii.) a toe pressure < 30 mmHg, iii.) a reduced TCPO2 < 30 mmHg, or iv.) a severely ischemic or flat line transtarsal pulse volume recording (i.e., Category V). Be males or females of at least 18 years old. Have agreed to participate voluntarily and signed and dated an IRB-approved, Patient Informed Consent form. Have a documented negative serum pregnancy test for all women of childbearing potential. Be using an acceptable method of birth control if of reproductive potential. Note: Patients undergoing operations to replace previously occluded grafts that involve placement of an entirely new bypass graft ARE eligible for this study.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Todd Lorenz, M.D.
Organizational Affiliation
Anesiva, Inc.
Official's Role
Study Director
Facility Information:
Facility Name
The Kirklin Clinic
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35233
Country
United States
Facility Name
University Hospital
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35294
Country
United States
Facility Name
Mobile Infirmary Medical Center
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36607
Country
United States
Facility Name
Vascular Specialists of Mobile, PC
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36607
Country
United States
Facility Name
Springhill Memorial Hopsital
City
Mobile
State/Province
Alabama
ZIP/Postal Code
36608
Country
United States
Facility Name
Tucson Heart Hospital
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85704
Country
United States
Facility Name
University Medical Center
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85724
Country
United States
Facility Name
Northwest Hospital
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85741
Country
United States
Facility Name
Tucson Vascular Surgery
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85741
Country
United States
Facility Name
Southern Arizona Vascular Institute
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85745
Country
United States
Facility Name
St. Mary's Hospital
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85745
Country
United States
Facility Name
Baptist Health
City
Little Rock
State/Province
Arkansas
ZIP/Postal Code
72205
Country
United States
Facility Name
Central Arkansas Veterans Healthcare System
City
Little Rock
State/Province
Arkansas
ZIP/Postal Code
72205
Country
United States
Facility Name
University of Arkansas for Medical Sciences Hospital
City
Little Rock
State/Province
Arkansas
ZIP/Postal Code
72205
Country
United States
Facility Name
Cedars-Sinai Medical Center
City
Los Angeles
State/Province
California
ZIP/Postal Code
90048
Country
United States
Facility Name
VA Palo Alto Health Care System
City
Palo Alto
State/Province
California
ZIP/Postal Code
94304
Country
United States
Facility Name
Kaiser Permanente - San Diego, SCPMG, Department of Surgery
City
San Diego
State/Province
California
ZIP/Postal Code
92120
Country
United States
Facility Name
Kaiser Permanente Franklin Medical Center
City
Denver
State/Province
Colorado
ZIP/Postal Code
80205
Country
United States
Facility Name
Exempla Healthcare Saint Joseph Hospital
City
Denver
State/Province
Colorado
ZIP/Postal Code
80218
Country
United States
Facility Name
Hartford Hospital
City
Hartford
State/Province
Connecticut
ZIP/Postal Code
06102
Country
United States
Facility Name
Washington Hospital Center, Center for Vascular Care
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20010
Country
United States
Facility Name
Malcom Randall VA Medical Center
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32608
Country
United States
Facility Name
Shands Hospital at the University of Florida
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32610
Country
United States
Facility Name
Samson Showalter Vascular Specialists
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34233
Country
United States
Facility Name
Clinical Research Center
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34239
Country
United States
Facility Name
Sarasota Memorial Hospital
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34239
Country
United States
Facility Name
Vascular & Surgery Assoc.
City
Sarasota
State/Province
Florida
ZIP/Postal Code
34239
Country
United States
Facility Name
Tampa General Hospital
City
Tampa
State/Province
Florida
ZIP/Postal Code
33601
Country
United States
Facility Name
Emory University School of Medicine Hospital
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30322
Country
United States
Facility Name
Saint Joseph's Hospital of Atlanta
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Facility Name
Vascular Institute of Georgia
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Facility Name
Atlanta VA Medical Center
City
Decatur
State/Province
Georgia
ZIP/Postal Code
30033
Country
United States
Facility Name
Northwestern Memorial Hospital
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60611
Country
United States
Facility Name
University of Chicago
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60637
Country
United States
Facility Name
Methodist Hospital
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46202
Country
United States
Facility Name
Veteran's Affairs Medical Center
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46202
Country
United States
Facility Name
Our Lady of the Lake Regional Medical Center
City
Baton Rouge
State/Province
Louisiana
ZIP/Postal Code
70808
Country
United States
Facility Name
Maine Medical Center
City
Portland
State/Province
Maine
ZIP/Postal Code
04102
Country
United States
Facility Name
University of Maryland Hospital
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21201
Country
United States
Facility Name
Johns Hopkins Hospital
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21287
Country
United States
Facility Name
New England Medical Center Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02111
Country
United States
Facility Name
Brigham & Women's Hospital
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02115
Country
United States
Facility Name
Beth-Israel Deaconess Medical Center
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Facility Name
Dept. of Surgery at Harvard Medical Faculty Physicians
City
Boston
State/Province
Massachusetts
ZIP/Postal Code
02215
Country
United States
Facility Name
William Beaumont Hospital
City
Royal Oak
State/Province
Michigan
ZIP/Postal Code
48073
Country
United States
Facility Name
O.W. Brown, M.D.
City
Southfield
State/Province
Michigan
ZIP/Postal Code
48075
Country
United States
Facility Name
Lakeland Hospital
City
St. Joseph
State/Province
Michigan
ZIP/Postal Code
49085
Country
United States
Facility Name
Steven D. Rimar, M.D.
City
Troy
State/Province
Michigan
ZIP/Postal Code
48098
Country
United States
Facility Name
St. Mary's Hospital
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55902
Country
United States
Facility Name
Mayo Clinic
City
Rochester
State/Province
Minnesota
ZIP/Postal Code
55905
Country
United States
Facility Name
Washington University School of Medicine
City
St. Louis
State/Province
Missouri
ZIP/Postal Code
63110
Country
United States
Facility Name
Methodist Hospital
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68114
Country
United States
Facility Name
Dartmouth Hitchcock Medical Center
City
Lebanon
State/Province
New Hampshire
ZIP/Postal Code
03756
Country
United States
Facility Name
Dr. Randy Shafrtiz, Clinical Office
City
Holmdel
State/Province
New Jersey
ZIP/Postal Code
07733
Country
United States
Facility Name
Morristown Memorial Hospital
City
Morristown
State/Province
New Jersey
ZIP/Postal Code
07960
Country
United States
Facility Name
Surgical Specialists of NJ, Morris Vascular Center
City
Morristown
State/Province
New Jersey
ZIP/Postal Code
07960
Country
United States
Facility Name
Robert Wood Johnson University Hospital
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08903
Country
United States
Facility Name
Umdnj-Rwjms
City
New Brunswick
State/Province
New Jersey
ZIP/Postal Code
08903
Country
United States
Facility Name
UMDNJ - New Jersey Medical School, University Hospital
City
Newark
State/Province
New Jersey
Country
United States
Facility Name
Albany Medical Center
City
Albany
State/Province
New York
ZIP/Postal Code
12208
Country
United States
Facility Name
Montefiore Hospital
City
Bronx
State/Province
New York
ZIP/Postal Code
10467
Country
United States
Facility Name
Kings County Hospital
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11203
Country
United States
Facility Name
SUNY Downstate University Hospital of Brooklyn and Medical School
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11203
Country
United States
Facility Name
Maimonides Medical Center
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11219
Country
United States
Facility Name
New York Presbyterian Hospital, Weill Medical College of Cornell University
City
New York
State/Province
New York
ZIP/Postal Code
10021
Country
United States
Facility Name
Mount Sinai Medical Center
City
New York
State/Province
New York
ZIP/Postal Code
10029
Country
United States
Facility Name
Columbia Presbyterian Medical Center
City
New York
State/Province
New York
ZIP/Postal Code
10032
Country
United States
Facility Name
University of Rochester Medical Center
City
Rochester
State/Province
New York
ZIP/Postal Code
14642
Country
United States
Facility Name
Gaston Memorial Hospital
City
Gastonia
State/Province
North Carolina
ZIP/Postal Code
28054
Country
United States
Facility Name
Pitt County Memorial Hospital
City
Greenville
State/Province
North Carolina
ZIP/Postal Code
27834
Country
United States
Facility Name
Department of Surgery, Division of Vascular Surgery, East Carolina University
City
Greenville
State/Province
North Carolina
ZIP/Postal Code
27858
Country
United States
Facility Name
Wake Forest University School of Medicine
City
Winston Salem
State/Province
North Carolina
ZIP/Postal Code
27157
Country
United States
Facility Name
Cleveland Clinic Foundation
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195
Country
United States
Facility Name
Flower Hospital
City
Sylvania
State/Province
Ohio
ZIP/Postal Code
43560
Country
United States
Facility Name
Jobst Vascular Center
City
Toledo
State/Province
Ohio
ZIP/Postal Code
43606
Country
United States
Facility Name
The Toledo Hospital
City
Toledo
State/Province
Ohio
ZIP/Postal Code
43606
Country
United States
Facility Name
Oregon Health Sciences University
City
Portland
State/Province
Oregon
ZIP/Postal Code
97201
Country
United States
Facility Name
Penn State College of Medicine
City
Hershey
State/Province
Pennsylvania
ZIP/Postal Code
17033
Country
United States
Facility Name
Hospital of the University of Pennsylvania
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19104
Country
United States
Facility Name
Temple University Hospital
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19140
Country
United States
Facility Name
Veterans Administration Healthcare System
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15240
Country
United States
Facility Name
Robert Packer Hospital
City
Sayre
State/Province
Pennsylvania
ZIP/Postal Code
18840
Country
United States
Facility Name
Rhode Island Hospital
City
Providence
State/Province
Rhode Island
ZIP/Postal Code
02905
Country
United States
Facility Name
Medical University of South Carolina Hospital
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29425
Country
United States
Facility Name
University of Tennessee Medical Center
City
Knoxville
State/Province
Tennessee
ZIP/Postal Code
37920
Country
United States
Facility Name
St. Thomas Medical
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37205
Country
United States
Facility Name
The Surgical Group, PLLC
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37205
Country
United States
Facility Name
Baylor College of Medicine
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
VAMC
City
Houston
State/Province
Texas
ZIP/Postal Code
77030
Country
United States
Facility Name
University Medical Center
City
Lubbock
State/Province
Texas
ZIP/Postal Code
79415
Country
United States
Facility Name
Texas Tech University Health Sciences Center
City
Lubbock
State/Province
Texas
ZIP/Postal Code
79430
Country
United States
Facility Name
Baptist Medical Center
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78205
Country
United States
Facility Name
Peripheral Vascular Associates
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78215
Country
United States
Facility Name
Northeast Baptist Hospital
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78217
Country
United States
Facility Name
Peripheral Vascular Associates
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78217
Country
United States
Facility Name
Pro-Research Group
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78224
Country
United States
Facility Name
Southwest Texas Methodist Hospital
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
University of Utah Hospital and Clinics
City
Salt Lake City
State/Province
Utah
ZIP/Postal Code
84132
Country
United States
Facility Name
Vascular and Transplant Specialists, Peripheral Vascular Laboratory
City
Chesapeake
State/Province
Virginia
ZIP/Postal Code
23320
Country
United States
Facility Name
Vascular and Transplant Specialsts, Peripheral and Vascular Laboratory
City
Chesapeake
State/Province
Virginia
ZIP/Postal Code
23320
Country
United States
Facility Name
Southampton Memorial Hospital
City
Franklin
State/Province
Virginia
ZIP/Postal Code
23851
Country
United States
Facility Name
Shore Memorial Hospital
City
Nassawadox
State/Province
Virginia
ZIP/Postal Code
23413
Country
United States
Facility Name
Chesapeake General Hospital
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Facility Name
Vascular and Transplant Specialists, Peripheral Vascular Laboratory
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Facility Name
Virginia Vascular Associates
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Facility Name
Sentara Norfolk General Hospital
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23507
Country
United States
Facility Name
Vascular and Transplant Specialists, Peripheral Vascular Laboratory
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23510
Country
United States
Facility Name
Carilion Roanoke Community Hospital
City
Roanoke
State/Province
Virginia
ZIP/Postal Code
24014
Country
United States
Facility Name
Carilion Roanoke Memorial Hospital
City
Roanoke
State/Province
Virginia
ZIP/Postal Code
24014
Country
United States
Facility Name
Jefferson Surgical Clinic
City
Roanoke
State/Province
Virginia
ZIP/Postal Code
24016
Country
United States
Facility Name
Harborview Medical Center
City
Seattle
State/Province
Washington
ZIP/Postal Code
98104
Country
United States
Facility Name
VA Puget Sound Health Care System
City
Seattle
State/Province
Washington
ZIP/Postal Code
98108
Country
United States
Facility Name
University of Washington Medical Center
City
Seattle
State/Province
Washington
ZIP/Postal Code
98195
Country
United States
Facility Name
Froedert Memorial Lutheran Hospital
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Facility Name
Medical College of Wisconsin
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Facility Name
Clement J. Zablocki VAMC
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53295
Country
United States
Facility Name
Peter Lougheed Centre
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T1Y6J4
Country
Canada
Facility Name
Vancouver Hospital & Health Sciences Centre
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z 1M9
Country
Canada
Facility Name
St. Boniface General Hospital
City
Winnipeg
State/Province
Manitoba
ZIP/Postal Code
R2H 2A6
Country
Canada
Facility Name
London Health Sciences Centre
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 4G5
Country
Canada
Facility Name
Ottawa Hospital
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
KIY 4E9
Country
Canada
Facility Name
University Health Network
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5G 2C4
Country
Canada
Facility Name
St. Paul's Hospital
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7M 0Z9
Country
Canada

12. IPD Sharing Statement

Learn more about this trial

Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures

We'll reach out to this number within 24 hrs