Back to results

Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

Primary Purpose

Headache, Epilepsy, Dizziness

Status

Unknown status

Phase

Phase 4

Locations

Germany

Study Type

Interventional

Intervention

Contrast agent

About this trial

This is an interventional diagnostic trial for Headache focused on measuring magnetic imaging, angiography, contrast agent, signal/noise ratio, contrast/noise ratio, vessel

Eligibility Criteria

18 Years - 60 Years (Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria: Headache Epilepsia Dizziness Exclusion Criteria: Pregnancy Metal implants (e.g. pacemaker) Contraindication for contrast agent Multiple allergies

Sites / Locations

University of Muenster, Dept. of Clinical RadiologyRecruiting

Outcomes

Primary Outcome Measures

intensity of vessels, muscle, air

Secondary Outcome Measures

signal/noise ratio

contrast/nose ratio

Full Information

NCT ID

NCT00132223

First Posted

August 18, 2005

Last Updated

April 11, 2006

Sponsor

University Hospital Muenster

1. Study Identification

Unique Protocol Identification Number

NCT00132223

Brief Title

Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

Official Title

Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients With Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging

Study Type

Interventional

2. Study Status

Record Verification Date

April 2006

Overall Recruitment Status

Unknown status

Study Start Date

April 2005 (undefined)

Primary Completion Date

undefined (undefined)

Study Completion Date

December 2005 (undefined)

3. Sponsor/Collaborators

Name of the Sponsor

University Hospital Muenster

4. Oversight

5. Study Description

Brief Summary

Angiographies of the supra-aortic vessels by magnetic imaging have become common recently. So it was the purpose of this study to evaluate the imaging potential of different contrast agents. Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients. All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s. The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Headache, Epilepsy, Dizziness

Keywords

magnetic imaging, angiography, contrast agent, signal/noise ratio, contrast/noise ratio, vessel

7. Study Design

Primary Purpose

Diagnostic

Study Phase

Phase 4

Interventional Study Model

Single Group Assignment

Masking

Single

Allocation

Non-Randomized

Enrollment

10 (false)

8. Arms, Groups, and Interventions

Intervention Type

Drug

Intervention Name(s)

Contrast agent

Primary Outcome Measure Information:

Title

intensity of vessels, muscle, air

Secondary Outcome Measure Information:

Title

signal/noise ratio

Title

contrast/nose ratio

10. Eligibility

Sex

All

Minimum Age & Unit of Time

18 Years

Maximum Age & Unit of Time

60 Years

Accepts Healthy Volunteers

Eligibility Criteria

Inclusion Criteria: Headache Epilepsia Dizziness Exclusion Criteria: Pregnancy Metal implants (e.g. pacemaker) Contraindication for contrast agent Multiple allergies

Central Contact Person:

First Name & Middle Initial & Last Name or Official Title & Degree

Boris Buerke, MD

Phone

00492518345123

buerkeb@uni-muenster.de

First Name & Middle Initial & Last Name or Official Title & Degree

Bernd Tombach, MD

Phone

00492518345123

tombach@uni-muenster.de

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Bernd Tombach, MD

Organizational Affiliation

University of Muenster, Dept. of Clinical Radiology

Official's Role

Study Chair

Facility Information:

Facility Name

University of Muenster, Dept. of Clinical Radiology

City

Muenster

ZIP/Postal Code

48129

Country

Germany

Individual Site Status

Recruiting

Facility Contact:

First Name & Middle Initial & Last Name & Degree

Boris Buerke, MD

Phone

00492518345123

buerkeb@uni-muenster.de

First Name & Middle Initial & Last Name & Degree

Bernd Tombach

Phone

00492518345123

tombach@uni-muenster.de

First Name & Middle Initial & Last Name & Degree

Bernd Tombach, MD

First Name & Middle Initial & Last Name & Degree

Boris Buerke, MD

12. IPD Sharing Statement

Learn more about this trial

Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

We'll reach out to this number within 24 hrs