Reducing the Weight of Overweight Schizophrenia Patients
Schizophrenia, Obesity
About this trial
This is an interventional treatment trial for Schizophrenia focused on measuring Weight Loss
Eligibility Criteria
Inclusion Criteria: Diagnosis of schizophrenia or schizoaffective disorder Body mass index (BMI) greater than 27 Stable on antipsychotic drug regimen for at least 1 month prior to study entry Parent or guardian willing to provide informed consent, if applicable Positive and negative syndrome scale score less than 90 Willing to use acceptable methods of contraception during the study Exclusion Criteria: Medical contraindication for participating in a weight reduction/exercise program Mental retardation Current enrollment in another weight management program Current use of weight reduction medication Unstable cardiovascular or thyroid disease Active or end-stage renal disease Psychiatric hospitalization within 1 month prior to study entry Current use of more than one anti-psychotic medication Pregnancy or breastfeeding
Sites / Locations
- Western Psychiatric Institute and Clinic of University of Pennsylvania Medical Center
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Active Comparator
Experimental
Experimental
1
2
3
4
Phase 1 participants who will receive behavioral training for 14 weeks
Phase 1 participants who will receive social skills training for 14 weeks
Participants in the Phase 1 behavioral training group who have a 4% or more weight loss and will be enrolled in weekly behavioral training alone for 24 months in Phase 2
Participants in the Phase 1 behavioral training group who have a 4% or more weight loss and will be enrolled in weekly behavioral training plus biweekly booster treatments for 24 months in Phase 2