Medication-overuse Headache (MOH): Withdrawal or Use of Preventative Medications Directly?
Headache
About this trial
This is an interventional treatment trial for Headache focused on measuring Medication-overuse headache, preventative medication, controls, follow-up, randomized, abrupt withdrawal
Eligibility Criteria
Inclusion Criteria: fulfill 8.2.7 probably medication-overuse headache according to the International Classification of Headache Disorders, 2th Edition (2004) Exclusion Criteria: No benefit of all available preventative medications no benefit of abrupt withdrawal lasting more than 3 weeks of acute medication that has been overused cluster headache chronic paroxysmal hemicrania hemicrania continua, pregnancy use of pain killers for other reasons than headache other reasons for chronic daily headache than medication-overuse
Sites / Locations
- Knut Hagen
Arms of the Study
Arm 1
Arm 2
Arm 3
Active Comparator
Other
Other
Prophylaxis from the start
Abrupt withdrawal
Controls
Use of preventive drugs from the start without abrupt withdrawal
Device: Abrupt withdrawal. Standard out-patients detoxication program including telephone call after 2 weeks and rescue medicine up to 2 days/week
Active control: No instruction for abrupt withdrawal or prophylactic treatment. The controls finished the study period after 5 months observation, and were then offered the optimal type of treatment