Back to resultsEffective Training in Overweight and Obese People
Primary Purpose
Obesity, Overweight
Status
Completed
Phase
Not Applicable
Locations
Norway
Study Type
Interventional
Intervention
Strength training
continuous moderate-intensity aerobic training
high-intensity interval aerobic training
Sponsored by
About this trial
This is an interventional treatment trial for Obesity focused on measuring aerobic capacity, endothelial function, exercise
Eligibility Criteria
Inclusion Criteria: Body mass index (BMI) over 30 Exclusion Criteria: Not able to walk on a treadmill Participating in an other study Serious cardiovascular diseases
Sites / Locations
- Norwegian University of Science and Technology
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm Type
Experimental
Experimental
Experimental
Arm Label
strength training
continuous moderate-intensity aerobic training
high-intensity interval aerobic training
Arm Description
Over a 12-week period, 13 subjects performed three programmed exercise sessions per week; two supervised by the study investigators in the research laboratory and one performed at home or in a gym, according to instructions.
Over a 12-week period, 13 subjects performed three programmed exercise sessions per week; two supervised by the study investigators in the research laboratory and one performed at home or in a gym, according to instructions.
Over a 12-week period, 14 subjects performed three programmed exercise sessions per week; two supervised by the study investigators in the research laboratory and one performed at home or in a gym, according to instructions.
Outcomes
Primary Outcome Measures
Body weight
Aerobic capacity
Endothelial function
Secondary Outcome Measures
Molecular markers in fat and skeletal muscle biopsies for the effects of exercise training
Full Information
NCT ID
NCT00218920
First Posted
September 20, 2005
Last Updated
October 13, 2017
Sponsor
Norwegian University of Science and Technology
1. Study Identification
Unique Protocol Identification Number
NCT00218920
Brief Title
Effective Training in Overweight and Obese People
Official Title
Effective Training in Overweight and Obesity
Study Type
Interventional
2. Study Status
Record Verification Date
October 2017
Overall Recruitment Status
Completed
Study Start Date
September 2005 (Actual)
Primary Completion Date
January 2008 (Actual)
Study Completion Date
January 2008 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Norwegian University of Science and Technology
4. Oversight
Studies a U.S. FDA-regulated Drug Product
No
Studies a U.S. FDA-regulated Device Product
No
5. Study Description
Brief Summary
The aim is to come to a consensus about how to prescribe exercise training that actually helps overweight and obese people. Thus, the present study determines the effects of several types of exercise training to define the one with the largest effect with the least effort.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity, Overweight
Keywords
aerobic capacity, endothelial function, exercise
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Factorial Assignment
Masking
Single
Allocation
Randomized
Enrollment
40 (Actual)
8. Arms, Groups, and Interventions
Arm Title
strength training
Arm Type
Experimental
Arm Description
Over a 12-week period, 13 subjects performed three programmed exercise sessions per week; two supervised by the study investigators in the research laboratory and one performed at home or in a gym, according to instructions.
Arm Title
continuous moderate-intensity aerobic training
Arm Type
Experimental
Arm Description
Over a 12-week period, 13 subjects performed three programmed exercise sessions per week; two supervised by the study investigators in the research laboratory and one performed at home or in a gym, according to instructions.
Arm Title
high-intensity interval aerobic training
Arm Type
Experimental
Arm Description
Over a 12-week period, 14 subjects performed three programmed exercise sessions per week; two supervised by the study investigators in the research laboratory and one performed at home or in a gym, according to instructions.
Intervention Type
Behavioral
Intervention Name(s)
Strength training
Intervention Description
a strength training regime of 4 series with 5 repetitions each, at approximately 90% of 1 repetition maximum (RM), in a leg press apparatus to develop maximal strength mainly from neural adaptation with minimal weight gain due to muscular hypertrophy.
Intervention Type
Behavioral
Intervention Name(s)
continuous moderate-intensity aerobic training
Intervention Description
The moderate-intensity group walked continuously for 47 min at 60-70% of maximum heart rate (HRmax) to ensure that the training protocols were isocaloric.
Intervention Type
Behavioral
Intervention Name(s)
high-intensity interval aerobic training
Intervention Description
High-intensity training consisted of a 10 min warm-up period at 50-60% of HRmax [maximal HR (heart rate)], followed by 4×4-min intervals at 85-95% of HRmax with 3 min active breaks in between the intervals, consisting of walking or jogging at 50-60% of HRmax. The exercise session was terminated by a 5 min cool-down period.
Primary Outcome Measure Information:
Title
Body weight
Time Frame
12 weeks
Title
Aerobic capacity
Time Frame
12 weeks
Title
Endothelial function
Time Frame
12 weeks
Secondary Outcome Measure Information:
Title
Molecular markers in fat and skeletal muscle biopsies for the effects of exercise training
Time Frame
12 weeks
10. Eligibility
Sex
All
Minimum Age & Unit of Time
20 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Body mass index (BMI) over 30
Exclusion Criteria:
Not able to walk on a treadmill
Participating in an other study
Serious cardiovascular diseases
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Ulrik Wisløff, phd
Organizational Affiliation
Norwegian University of Science and Technology
Official's Role
Principal Investigator
Facility Information:
Facility Name
Norwegian University of Science and Technology
City
Trondheim
ZIP/Postal Code
7489
Country
Norway
12. IPD Sharing Statement
Citations:
PubMed Identifier
18338980
Citation
Schjerve IE, Tyldum GA, Tjonna AE, Stolen T, Loennechen JP, Hansen HE, Haram PM, Heinrich G, Bye A, Najjar SM, Smith GL, Slordahl SA, Kemi OJ, Wisloff U. Both aerobic endurance and strength training programmes improve cardiovascular health in obese adults. Clin Sci (Lond). 2008 Nov;115(9):283-93. doi: 10.1042/CS20070332.
Results Reference
result
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Effective Training in Overweight and Obese People
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