Treatment of Supine Hypertension in Autonomic Failure
Hypertension
About this trial
This is an interventional treatment trial for Hypertension focused on measuring Supine Hypertension, Hypertension, Treatment, Autonomic failure, Pure autonomic failure, Multiple System Atrophy, Shy-Drager Syndrome
Eligibility Criteria
Inclusion Criteria: Patients with autonomic failure and with supine hypertension from all races Exclusion Criteria: All medical students Pregnant women High-risk patients (e.g. heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction) History of serious allergies or asthma.
Sites / Locations
- Vanderbilt University
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
1: Active drug or intervention
2: Placebo
Clonidine, Nitroglycerin transdermal, Dipyridamole/ Aspirin (Aggrenox), Desmopressin (DDAVP), Sildenafil, Nifedipine, Hydralazine, Hydrochlorothiazide, Bosentan, Diltiazem, Eplerenone, guanfacine, L-arginine, captopril, carbidopa, losartan, metoprolol tartrate, nebivolol hydrochloride, prazosin hydrochloride, tamsulosin hydrochloride, Head-up tilt, aliskiren, local heat stress
placebo pill or patch