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Active clinical trials for "Hypertension"

Results 1-10 of 5863

A Study to Evaluate the Efficacy and Safety of AD-209

HypertensionEssential

The purpose of this study is to evaluate the efficacy and safety of AD-209

Recruiting4 enrollment criteria

MK-5475-013 INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of MK-5475 (an Inhaled sGC Stimulator)...

Pulmonary HypertensionChronic Obstructive Pulmonary Disease

The purpose of this study is to evaluate the safety and efficacy of once daily oral inhalation dose of MK-5475 380 µg in participants 40 to 80 years (inclusive) with Pulmonary Hypertension associated with Chronic Obstructive Pulmonary Disease (PH-COPD). The primary hypothesis of the study is MK-5475, a soluble Guanylate Cyclase (sGC) stimulator is superior to placebo in increasing 6 Minute Walking Distance (6MWD) from baseline at Week 24.

Recruiting28 enrollment criteria

Satralizumab in the Treatment of Pulmonary Arterial Hypertension (SATISFY-JP Trial)

Pulmonary Arterial Hypertension

Examine the efficacy of satralizumab in patients with pulmonary arterial hypertension (PAH) with immune-responsive phenotype serum interleukin-6 (IL-6) ≥ 2.73 pg/mL who have an inadequate response to existing drugs.

Recruiting25 enrollment criteria

CSF Biomarkers in Idiopathic Intracranial Hypertension

Intracranial Hypertension

Aim of the study is to high lighten the rule of CSF biomarkers in early diagnosis of IIH and in follow up to reach to a definite clinically based decision if this patient will improved on medical treatment or that patient is in need for surgical intervention.

Recruiting5 enrollment criteria

Mobile Health Program for Rural Hypertension

Hypertension,EssentialAdherence2 more

Hypertension (HTN) is the leading modifiable cause of cardiovascular disease. Rural individuals experience challenges of the rural health divide: geographic distance from providers, social isolation, limited social resources, and high rates of low health literacy. This study evaluates a home-based blood pressure monitoring (HBPM) program that provides longitudinal health education, empathic guidance, monitoring, and adaptable patient-centered coaching to rural individuals. Participants in this study will be randomized to receive (1) HBPM with the intervention; or (2) the control, consisting of HBPM and a smartphone with a general health application (WebMD).

Recruiting14 enrollment criteria

Intelligent Hypertension Intervention Study

To Explore Whether the Application of Intelligent Hypertension Management System Can Effectively Reduce Blood Pressure in Hypertensive Patients

To explore whether the application of intelligent hypertension management system can effectively reduce blood pressure in hypertensive patients. A total of 320 eligible subjects will be recruited and randomization to two groups. The standard care group (n=160) will receive conventional hypertension treatment with baseline data collected.Wearable blood pressure monitoring device management group (intervention group, n=160) will receive blood pressure monitoring remotely everyday and antihypertension medication treatment. Primary outcome is Net change in systolic blood pressure from baseline to 3 months follow-up. Secondary outcomes include Net change in diastolic blood pressure hypertension control ratio (BP < 140/90 mmHg)

Recruiting10 enrollment criteria

A Long Term Study of STN1012600 in Subjects With Open Angle Glaucoma or Ocular Hypertension

Open Angle GlaucomaOcular Hypertension

To evaluate safety and the ocular hypotensive effect of STN1012600 ophthalmic solution 0.002% alone or in combination with Timolol ophthalmic solution 0.5% for 52 weeks in subjects with open angle glaucoma or ocular hypertension.

Recruiting13 enrollment criteria

The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions...

Pregnancy RelatedHypertension2 more

The overarching goal of our proposal is to reduce disparities in perinatal cardiovascular disease risk factors among Black women utilizing a community-driven, social ecological framework.

Recruiting5 enrollment criteria

Efficacy and Safety Evaluation of Tolvaptan in the Treatment of Patients With RHF Caused by PAH...

Pulmonary Arterial HypertensionRandomized Controlled Trial

Efficacy and safety evaluation of tolvaptan in the treatment of patients with right heart failure caused by pulmonary arterial hypertension

Recruiting14 enrollment criteria

A Study of Pulmonary Hypertension Peripheral Limitations

Pulmonary Arterial HypertensionHealthy

The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and quality of life in patients with Pulmonary Arterial Hypertension (PAH).

Recruiting23 enrollment criteria
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