MINERVA: MINimizE Right Ventricular Pacing to Prevent Atrial Fibrillation and Heart Failure

Inclusion Criteria: Class I/Class II indications for dual chamber pacing Previous implant of an EnRhythm dual chamber implantable pulse generator (IPG) since maximum 2 weeks History of atrial arrhythmias (at least one electrocardiogram [ECG] or Holter documented episodes in the last 12 months) Exclusion Criteria: Less than 18 years of age Pregnancy Unwilling or unable to give informed consent or to commit to follow-up schedule Medical conditions that preclude protocol required testing or limit study participation Enrolled or intend to participate in another clinical trial during the course of this study A life expectancy of less than 2 years Patient is a candidate for an implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy (CRT) device implant Anticipated major cardiac surgery within the course of this study Permanent III degree AV-block or history of AV node ablation History of permanent AF (as defined below) AF ablation (left pulmonary veins) or other cardiac surgery < 3 months Prior implant of defibrillator device or pacemaker (apart from EnRhythm IPG implanted within two weeks) Uncontrolled hyperthyroidism