BreathID Multi-center HCV Liver Breath Test Study
Hepatitis C
About this trial
This is an interventional diagnostic trial for Hepatitis C focused on measuring HCV (Hepatitis C Virus), MBT (Methacetin Breath Test), Hepatitis C Virus Patients
Eligibility Criteria
Inclusion Criteria: i. Patients with a confirmed diagnosis of Chronic HCV only : ii. Patients for whom a liver biopsy has been performed within the last 90 days or who will undergo a liver biopsy within the time frame of the study. Exclusion Criteria: i. Severe congestive heart failure. ii. Severe pulmonary hypertension. iii.Chronic renal insufficiency defined by a serum creatinine above the limits of normal. iv. Uncontrolled diabetes mellitus (need definition).v.Any autoimmune disorder, which is currently being treated with prednisone or any other immune suppressive medication. vi.Proven or suspected hepatocellular carcinoma. vii. Previous surgical bypass surgery for morbid obesity viii.Extensive small bowel resection. ix.Patients currently receiving total parenteral nutrition x.Recipients of any organ transplant. xi.Other co-existent liver disease.
Sites / Locations
- Mount Sinai School of Medicine
- Baylor College of Medicine
- U.S. Dept. of Veteran Affairs, Hunter Holmes McGuire Medical Center
- Virginia Commonwealth Univeristy
- Hadassah Medical Center
Arms of the Study
Arm 1
Experimental
MBT
C13 methacetin dissolved in water to be ingested after breath baseline collected. Metabolism to measured in real time.