Back to resultsVLDL-triglyceride Under Acute Hyperinsulinaemia
Primary Purpose
Obesity
Status
Completed
Phase
Locations
Denmark
Study Type
Observational
Intervention
Food (fat free meal)
Sponsored by
About this trial
This is an observational trial for Obesity focused on measuring VLDL, Kinetics, Hyperinsulinaemia, Obesity
Eligibility Criteria
Inclusion Criteria:
- Written consent
Exclusion Criteria:
- Known diseases
- Alcohol abuse
- Smoker
- Regular use of medicine
Sites / Locations
- Department of Endocrinology M, Aarhus Hospital
Arms of the Study
Arm 1
Arm 2
Arm Type
Arm Label
1
2
Arm Description
Lean male
Males with type 2 diabetes
Outcomes
Primary Outcome Measures
VLDL metabolism
Secondary Outcome Measures
Full Information
NCT ID
NCT00624104
First Posted
February 18, 2008
Last Updated
November 4, 2011
Sponsor
University of Aarhus
1. Study Identification
Unique Protocol Identification Number
NCT00624104
Brief Title
VLDL-triglyceride Under Acute Hyperinsulinaemia
Official Title
VLDL-triglyceride Under Acute Hyperinsulinaemia
Study Type
Observational
2. Study Status
Record Verification Date
November 2011
Overall Recruitment Status
Completed
Study Start Date
March 2008 (undefined)
Primary Completion Date
December 2010 (Actual)
Study Completion Date
December 2010 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
University of Aarhus
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The purpose of the study is to investigate and compare the lipid metabolism in lean and obese individuals. We want to investigate the effect of postprandial hyperinsulinaemia on VLDL-triglyceride metabolism
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity
Keywords
VLDL, Kinetics, Hyperinsulinaemia, Obesity
7. Study Design
Enrollment
16 (Actual)
Biospecimen Retention
Samples With DNA
Biospecimen Description
specimen of muscle specimen of adipose tissue
8. Arms, Groups, and Interventions
Arm Title
1
Arm Description
Lean male
Arm Title
2
Arm Description
Males with type 2 diabetes
Intervention Type
Dietary Supplement
Intervention Name(s)
Food (fat free meal)
Intervention Description
Fat free meal (40% of REE)
Primary Outcome Measure Information:
Title
VLDL metabolism
Time Frame
Few hours
10. Eligibility
Sex
Male
Minimum Age & Unit of Time
20 Years
Maximum Age & Unit of Time
65 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
- Written consent
Exclusion Criteria:
Known diseases
Alcohol abuse
Smoker
Regular use of medicine
Study Population Description
Males with diabetes from departments out-patient clinic. Control group of healthyt volunteers
Sampling Method
Non-Probability Sample
Facility Information:
Facility Name
Department of Endocrinology M, Aarhus Hospital
City
Aarhus C
ZIP/Postal Code
8000
Country
Denmark
12. IPD Sharing Statement
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VLDL-triglyceride Under Acute Hyperinsulinaemia
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