Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats
Pharyngitis
About this trial
This is an interventional treatment trial for Pharyngitis focused on measuring Sore throats,, Pharyngitis, Acute
Eligibility Criteria
Inclusion Criteria:
- Age > 12 years;
- Acute pharyngitis or tonsillitis with symptoms of throat pain and inflammation of the pharynx and/or tonsils;
- Onset of sore throat less than 72 hours before inclusion ;
- A Tonsillopharyngitis Severity Score ≥6;
- Written informed consent.
Exclusion Criteria:
- Analgesics <12 hours;
- Antibiotics <24 hours; t
- Topical throat pain medication <4 hours;
- Systemic corticosteroids within the last month;
- Symptoms of primary bacterial pharyngitis or secondary bacterial infection;
- Serious illness such as tumors; allergy to one of the ingredients; pregnancy or lactation;
- Hypersensitivity to ibuprofen;
- Participation in another clinical trial in the previous 30 days.
Sites / Locations
- Allergy Clinic
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
2
1
Drug: Echinacea/sage patients received additionally a placebo-spray for the synthetical comparator (chlorhexidine/lidocaine) as the study was double dummy blinded. Patients had to apply spray every 2 hours with two puffs to the pharyngeal area up to a maximum of 10 times daily. Treatment duration was until illness was resolved or for a maximum of 5 consecutive days. Arms: 1
Drug: Chlorhexidine/lidocaine patients received additionally a placebo-spray for the synthetical comparator (echinacea/sage) as the study was double dummy blinded. Patients had to apply spray every 2 hours with two puffs to the pharyngeal area up to a maximum of 10 times daily. Treatment duration was until illness was resolved or for a maximum of 5 consecutive days.