Walking, Spontaneous Physical Activity and Lipid Oxidation After Dietary Treatment of Obesity
Primary Purpose
Obesity
Status
Unknown status
Phase
Not Applicable
Locations
France
Study Type
Interventional
Intervention
walking activity
Sponsored by
About this trial
This is an interventional basic science trial for Obesity focused on measuring Obesity, Weight loss maintenance, Spontaneous physical activity, Lipid oxydation, Walking
Eligibility Criteria
Inclusion Criteria:
- Women from 18 to 50 year-old
- In phase of weight stability
- BMI<40kg/m²
Exclusion Criteria:
- History of bariatric surgery
- Diabetes
- Suspicion of obstructive sleep apnea syndrome
Sites / Locations
- Service de Médecine Interne - Nutrition / CHRU de ToursRecruiting
Outcomes
Primary Outcome Measures
Daily time of moderate physical activity, inactivity and total physical activity measured by a portable monitor of physical activity
Secondary Outcome Measures
Daily energy expenditure and respiratory quotient during a stay in a respiration chamber
Full Information
NCT ID
NCT00775970
First Posted
October 17, 2008
Last Updated
October 17, 2008
Sponsor
University Hospital, Tours
1. Study Identification
Unique Protocol Identification Number
NCT00775970
Brief Title
Walking, Spontaneous Physical Activity and Lipid Oxidation After Dietary Treatment of Obesity
Official Title
Influence of Walking on Spontaneous Physical Activity and on Lipid Oxidation Following Dietary Treatment of Obesity
Study Type
Interventional
2. Study Status
Record Verification Date
October 2008
Overall Recruitment Status
Unknown status
Study Start Date
May 2008 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
undefined (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
University Hospital, Tours
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
The purpose of this study is to determine whether walking exercise after dietary treatment of obesity is associated with a decrease of the daily spontaneous physical activity and\or with an increase of the time spent in sedentary activities. Our hypothesis is that the practice of walking as an exercise during the phase of weight stability following the dietary treatment of obesity leads to a reduction of spontaneous physical activity and\or to an increase in the time spent in sedentary activities.
Detailed Description
The subjects of this study will be randomised in 2 groups:
A group with usual follow-up and a group with usual follow-up associated with recommendations to introduce a program of walking achieving gradually 2000-2500 kcal/week.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity
Keywords
Obesity, Weight loss maintenance, Spontaneous physical activity, Lipid oxydation, Walking
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Participant
Allocation
Randomized
Enrollment
20 (Anticipated)
8. Arms, Groups, and Interventions
Intervention Type
Behavioral
Intervention Name(s)
walking activity
Primary Outcome Measure Information:
Title
Daily time of moderate physical activity, inactivity and total physical activity measured by a portable monitor of physical activity
Time Frame
10 weeks
Secondary Outcome Measure Information:
Title
Daily energy expenditure and respiratory quotient during a stay in a respiration chamber
Time Frame
10 weeks
10. Eligibility
Sex
Female
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
50 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Women from 18 to 50 year-old
In phase of weight stability
BMI<40kg/m²
Exclusion Criteria:
History of bariatric surgery
Diabetes
Suspicion of obstructive sleep apnea syndrome
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
David JACOBI, MD
Phone
+33247474727
Email
jacobi@med.univ-tours.fr
First Name & Middle Initial & Last Name or Official Title & Degree
Pascaline RAMEAU, CRA
Phone
+33247366249
Email
rameau@med.univ-tours.fr
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
David JACOBI, MD
Organizational Affiliation
Service de médecine Interne-Nutrition
Official's Role
Principal Investigator
Facility Information:
Facility Name
Service de Médecine Interne - Nutrition / CHRU de Tours
City
Tours
ZIP/Postal Code
37044
Country
France
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
David JACOBI, MD
Phone
+33247472269
Email
jacobi@med.univ-tours.fr
First Name & Middle Initial & Last Name & Degree
David JACOBI, MD
First Name & Middle Initial & Last Name & Degree
Charles COUET, PhD
12. IPD Sharing Statement
Citations:
PubMed Identifier
12972441
Citation
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Results Reference
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PubMed Identifier
12119991
Citation
Fogelholm M, Kukkonen-Harjula K. Does physical activity prevent weight gain--a systematic review. Obes Rev. 2000 Oct;1(2):95-111. doi: 10.1046/j.1467-789x.2000.00016.x.
Results Reference
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PubMed Identifier
8416662
Citation
Froidevaux F, Schutz Y, Christin L, Jequier E. Energy expenditure in obese women before and during weight loss, after refeeding, and in the weight-relapse period. Am J Clin Nutr. 1993 Jan;57(1):35-42. doi: 10.1093/ajcn/57.1.35.
Results Reference
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PubMed Identifier
6650455
Citation
Jequier E, Schutz Y. Long-term measurements of energy expenditure in humans using a respiration chamber. Am J Clin Nutr. 1983 Dec;38(6):989-98. doi: 10.1093/ajcn/38.6.989.
Results Reference
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PubMed Identifier
9216973
Citation
Kraemer WJ, Volek JS, Clark KL, Gordon SE, Incledon T, Puhl SM, Triplett-McBride NT, McBride JM, Putukian M, Sebastianelli WJ. Physiological adaptations to a weight-loss dietary regimen and exercise programs in women. J Appl Physiol (1985). 1997 Jul;83(1):270-9. doi: 10.1152/jappl.1997.83.1.270.
Results Reference
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PubMed Identifier
9880251
Citation
Levine JA, Eberhardt NL, Jensen MD. Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science. 1999 Jan 8;283(5399):212-4. doi: 10.1126/science.283.5399.212.
Results Reference
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PubMed Identifier
11101470
Citation
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Results Reference
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PubMed Identifier
9252491
Citation
Nicklas BJ, Rogus EM, Goldberg AP. Exercise blunts declines in lipolysis and fat oxidation after dietary-induced weight loss in obese older women. Am J Physiol. 1997 Jul;273(1 Pt 1):E149-55. doi: 10.1152/ajpendo.1997.273.1.E149.
Results Reference
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PubMed Identifier
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Citation
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Results Reference
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PubMed Identifier
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Citation
van Aggel-Leijssen DP, Saris WH, Wagenmakers AJ, Hul GB, van Baak MA. The effect of low-intensity exercise training on fat metabolism of obese women. Obes Res. 2001 Feb;9(2):86-96. doi: 10.1038/oby.2001.11.
Results Reference
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Citation
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Results Reference
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Walking, Spontaneous Physical Activity and Lipid Oxidation After Dietary Treatment of Obesity
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