Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty
Primary Purpose
Osteoarthritis of Knee
Status
Unknown status
Phase
Phase 4
Locations
Korea, Republic of
Study Type
Interventional
Intervention
Mobile bearing
Fixed bearing
Sponsored by
About this trial
This is an interventional treatment trial for Osteoarthritis of Knee focused on measuring Total knee arthroplasty, Mobile bearing, Fixed bearing, Range of motion, Knee Society Score
Eligibility Criteria
Inclusion Criteria:
- primary total knee arthroplasty
Exclusion Criteria:
- infection
- severe deformity in knee
- revision
Sites / Locations
- Seoul National University Hospital
Arms of the Study
Arm 1
Arm 2
Arm Type
Active Comparator
Active Comparator
Arm Label
Mobile bearing
Fixed bearing
Arm Description
Mobile bearing type between polyethylene insert and tibial component MB type will be randomly used in total knee arthroplasty
Fixed bearing type between polyethylene insert and tibial component FB type will be randomly used in total knee arthroplasty
Outcomes
Primary Outcome Measures
Rotational Angle Between Femur and Tibia
Secondary Outcome Measures
Knee Society Score
Full Information
NCT ID
NCT01027819
First Posted
December 7, 2009
Last Updated
December 13, 2012
Sponsor
Seoul National University Hospital
1. Study Identification
Unique Protocol Identification Number
NCT01027819
Brief Title
Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty
Official Title
Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty
Study Type
Interventional
2. Study Status
Record Verification Date
December 2012
Overall Recruitment Status
Unknown status
Study Start Date
November 2009 (undefined)
Primary Completion Date
December 2013 (Anticipated)
Study Completion Date
undefined (undefined)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Seoul National University Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
The purpose of this study is to compare the clinical and radiological outcomes of mobile-bearing with that of fixed-bearing in total knee arthroplasty.
Detailed Description
Double blind, randomized prospective study Mobile or fixed bearing of the same company
Mobile bearing group : group M
Fixed bearing group : group F
Inclusion criteria
patients expected primary total knee arthroplasty without severe deformity
Clinical outcomes
Range of motion
Complication
Scorings
KSS, KSFS, HSS score, WOMAC score, Oxford score, SF-36
Radiological outcomes
Alignment angles in knee
Positions of femoral and tibial components
Position of patella
Radiolucency
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Osteoarthritis of Knee
Keywords
Total knee arthroplasty, Mobile bearing, Fixed bearing, Range of motion, Knee Society Score
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 4
Interventional Study Model
Parallel Assignment
Masking
ParticipantCare ProviderInvestigatorOutcomes Assessor
Allocation
Randomized
Enrollment
80 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Mobile bearing
Arm Type
Active Comparator
Arm Description
Mobile bearing type between polyethylene insert and tibial component MB type will be randomly used in total knee arthroplasty
Arm Title
Fixed bearing
Arm Type
Active Comparator
Arm Description
Fixed bearing type between polyethylene insert and tibial component FB type will be randomly used in total knee arthroplasty
Intervention Type
Device
Intervention Name(s)
Mobile bearing
Other Intervention Name(s)
Zimmer LPS-flex mobile bearing type polyethylene insert
Intervention Description
Mobile bearing in total knee arthroplasty
Intervention Type
Device
Intervention Name(s)
Fixed bearing
Other Intervention Name(s)
Zimmer LPS-flex fixed bearing in polyethylene insert
Intervention Description
Fixed bearing in total knee arthroplasty
Primary Outcome Measure Information:
Title
Rotational Angle Between Femur and Tibia
Time Frame
2 weeks
Secondary Outcome Measure Information:
Title
Knee Society Score
Time Frame
6 months
10. Eligibility
Sex
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
primary total knee arthroplasty
Exclusion Criteria:
infection
severe deformity in knee
revision
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Myung Chul Lee, M.D., Ph. D.
Official's Role
Study Director
Facility Information:
Facility Name
Seoul National University Hospital
City
Seoul
Country
Korea, Republic of
12. IPD Sharing Statement
Learn more about this trial
Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty
We'll reach out to this number within 24 hrs