Evaluating the Effectiveness of LACTOFOS in Constipated Patients (COSI)

This is an interventional treatment trial for Constipation focused on measuring Symbiotics, Fiber, Constipation Read More

Inclusion Criteria:

1. Females aged 18-75 years
2. A diagnosis of constipation defined by Rome III criteria
3. Ability to good communication with the investigator and agreeing to requests from the entire study
4. Patients must sign a formal consent to participate

Exclusion Criteria:

1. Constipation drug source
2. History or evidence of organic disease of the gastrointestinal tract such as tumors, inflammatory bowel disease, etc.. proven by radiological or endoscopic examination of the bowel (five years before and after onset of symptoms). If the investigator has doubts should request the necessary procedures, such as sigmoidoscopy, colonoscopy or edema bariatric to exclude organic disease
3. History of laxative use which in the opinion of the investigator is consistent with severe laxative dependence
4. Current History recent (12 months) of significant abuse of alcohol or drugs
5. History of malignancy in 5 (five) previous years (except basal cell carcinoma treated well or cervical carcinoma in situ)
6. Known history of cardiovascular control inappropriate and / or significant respiratory, renal, hepatic, gastrointestinal, hematological, neurological, psychiatric or other illness which compromises the ability of patients to participate in the full study
7. Use of investigational drugs in the previous month or intentional use of such drugs during the study
8. Intention of regular use of other medications that affect intestinal motility and / or perceived
9. Lactose malabsorption is not treatable. If clinical suspicion of lactose intolerance, the procedure for proper diagnosis should be made to establish or exclude a diagnosis. If malabsorption is diagnosed, the patient should receive appropriate conditions of treatment