Back to resultsA Comparison of Beverages Consumed Within a Meal to Satiation on Meal-time Food Intake and Post-meal Appetite and Glycemic Response in Healthy Young Adults
Primary Purpose
Obesity, Hyperglycemia
Status
Completed
Phase
Not Applicable
Locations
Canada
Study Type
Interventional
Intervention
Nutritional Intervention
Sponsored by
About this trial
This is an interventional basic science trial for Obesity
Eligibility Criteria
Inclusion Criteria:
- healthy men and women
- age 20-30 years
- BMI between 20-24.9 kg/m^2
Exclusion Criteria:
- breakfast skippers
- diabetes or any metabolic diseases
- lactose intolerance or allergies to milk
- taking medications
Sites / Locations
- University of Toronto, Department of Nutritional Sciences
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm Type
Experimental
Experimental
Experimental
Experimental
Placebo Comparator
Arm Label
1% Milk
Regular Cola
Diet cola
Orange juice
Water
Arm Description
Outcomes
Primary Outcome Measures
Food Intake
Measurement of energy intake during an ad libitum test meal
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT01595919
Brief Title
A Comparison of Beverages Consumed Within a Meal to Satiation on Meal-time Food Intake and Post-meal Appetite and Glycemic Response in Healthy Young Adults
Study Type
Interventional
2. Study Status
Record Verification Date
June 2012
Overall Recruitment Status
Completed
Study Start Date
April 2011 (undefined)
Primary Completion Date
December 2011 (Actual)
Study Completion Date
December 2011 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
University of Toronto
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
The objective of the current study is to determine the effects of an ad libitum intake of 1% milk, fruit juice, regular cola, diet cola and water, as part of a pizza meal, on meal food intake, appetite and postprandial blood glucose in healthy men and women. We hypothesize that 1% milk will reduce food intake and result in better post-meal glycemic response compared to the other beverages.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity, Hyperglycemia
7. Study Design
Primary Purpose
Basic Science
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
Participant
Allocation
Randomized
Enrollment
26 (Actual)
8. Arms, Groups, and Interventions
Arm Title
1% Milk
Arm Type
Experimental
Arm Title
Regular Cola
Arm Type
Experimental
Arm Title
Diet cola
Arm Type
Experimental
Arm Title
Orange juice
Arm Type
Experimental
Arm Title
Water
Arm Type
Placebo Comparator
Intervention Type
Other
Intervention Name(s)
Nutritional Intervention
Intervention Description
Ad libitum amounts of beverage at a meal
Primary Outcome Measure Information:
Title
Food Intake
Description
Measurement of energy intake during an ad libitum test meal
Time Frame
2 hours
10. Eligibility
Sex
All
Minimum Age & Unit of Time
20 Years
Maximum Age & Unit of Time
30 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
healthy men and women
age 20-30 years
BMI between 20-24.9 kg/m^2
Exclusion Criteria:
breakfast skippers
diabetes or any metabolic diseases
lactose intolerance or allergies to milk
taking medications
Facility Information:
Facility Name
University of Toronto, Department of Nutritional Sciences
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M5S 3E2
Country
Canada
12. IPD Sharing Statement
Citations:
PubMed Identifier
25700893
Citation
El Khoury D, Panahi S, Luhovyy BL, Douglas Goff H, Harvey Anderson G. Interaction of mealtime ad libitum beverage and food intake with meal advancement in healthy young men and women. Physiol Behav. 2015 May 1;143:39-44. doi: 10.1016/j.physbeh.2015.02.023. Epub 2015 Feb 18.
Results Reference
derived
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A Comparison of Beverages Consumed Within a Meal to Satiation on Meal-time Food Intake and Post-meal Appetite and Glycemic Response in Healthy Young Adults
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