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Early Strength Training After Hip Fracture Surgery

Primary Purpose

Hip Fractures

Status
Completed
Phase
Not Applicable
Locations
Denmark
Study Type
Interventional
Intervention
Knee-extension strength training of the fractured limb
Sponsored by
Copenhagen University Hospital, Hvidovre
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Hip Fractures focused on measuring Hip fractures, Strength training

Eligibility Criteria

60 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • Hip fracture diagnosed patients age ≥60 years, admitted to the acute hip fracture unit.
  • Medial femoral neck fracture, pertrochanteric fracture or subtrochanteric fracture.
  • Ability to speak and understand the Danish language.
  • Cognitively well-preserved and able to give personal informed consent no later than by 5th post surgical day.
  • Home-residing and with an independent pre-fracture ability to walk equal to New Mobility Score at ≥ 2 indoor.

Exclusion Criteria:

  • Multiple fractures
  • Postsurgical restrictions of mobilization
  • Patient not accepting participation in relevant exercise therapy
  • Fracture caused by cancer metastases
  • Terminal illness
  • Neurological impairment e.g. hemi paresis.

Sites / Locations

  • Copenhagen University Hospital, Hvidovre

Arms of the Study

Arm 1

Arm Type

Experimental

Arm Label

Strength training, fractured limb

Arm Description

Knee-extension strength training of the fractured limb: Daily knee-extension strength training with 3 x 10 repetitions using an intensity of 10 Repetition Maximum (RM) for the hip fractured limb started as soon as possible after surgery.

Outcomes

Primary Outcome Measures

Feasibility of progression in training loads (kg) during daily knee-extension strength training when commenced immediately after hip fracture surgery.
Feasibility is evaluated on the basis of adherence to program, adverse events, target training intensity, hip pain during training and other potential restricting factors, e.g. confusion, exhaustion and dropouts.

Secondary Outcome Measures

Change in maximum isometric knee-extension strength and strength deficits, fractured % of non-fractured limb measured by handheld dynamometer.

Full Information

First Posted
June 5, 2012
Last Updated
May 14, 2014
Sponsor
Copenhagen University Hospital, Hvidovre
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1. Study Identification

Unique Protocol Identification Number
NCT01616030
Brief Title
Early Strength Training After Hip Fracture Surgery
Official Title
Feasibility of Progressive Strength Training in the Early Post Surgical Rehabilitation Period After Hip Fracture Surgery
Study Type
Interventional

2. Study Status

Record Verification Date
May 2014
Overall Recruitment Status
Completed
Study Start Date
June 2012 (undefined)
Primary Completion Date
March 2013 (Actual)
Study Completion Date
March 2013 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Copenhagen University Hospital, Hvidovre

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
Patients treated surgically for a hip fracture have a need of rehabilitation for the regain of former functional skills. Despite an optimized fast track in-hospital rehabilitation program it has been found that patients with hip fracture within 2 weeks after the hip fracture loose more than half of their muscle strength in the fractured limb compared to non-fractured limb. New studies including patients with total hip arthroplasty and strength training applied early after surgery has shown promising results regarding prevention of loss of muscle strength. No similar study has been found including patients with hip fracture. The purpose of this study is to examine the feasibility of progressive knee-extension strength training of the hip fractured limb, starting Day 1 after surgical treatment for a hip fracture and proceeded every weekday during their hospital stay. The study will include 20 patients surgically treated for a cervical hip fracture and 20 patients surgically treated for an intertrochanteric or subtrochanteric fracture. All patients are admitted from their own home. Age 60 years or older.
Detailed Description
Kronborg L, Bandholm T, Palm H, Kehlet H, Kristensen MT (2014) Feasibility of Progressive Strength Training Implemented in the Acute Ward after Hip Fracture Surgery. PLoS ONE 9(4): e93332. doi:10.1371/journal.pone.0093332

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hip Fractures
Keywords
Hip fractures, Strength training

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
N/A
Enrollment
36 (Actual)

8. Arms, Groups, and Interventions

Arm Title
Strength training, fractured limb
Arm Type
Experimental
Arm Description
Knee-extension strength training of the fractured limb: Daily knee-extension strength training with 3 x 10 repetitions using an intensity of 10 Repetition Maximum (RM) for the hip fractured limb started as soon as possible after surgery.
Intervention Type
Other
Intervention Name(s)
Knee-extension strength training of the fractured limb
Intervention Description
Daily knee-extension strength training with 3 x 10 repetitions using an intensity of 10 Repetition Maximum (RM) for the hip fractured limb started as soon as possible after surgery.
Primary Outcome Measure Information:
Title
Feasibility of progression in training loads (kg) during daily knee-extension strength training when commenced immediately after hip fracture surgery.
Description
Feasibility is evaluated on the basis of adherence to program, adverse events, target training intensity, hip pain during training and other potential restricting factors, e.g. confusion, exhaustion and dropouts.
Time Frame
Baseline to discharge, in average 10 days.
Secondary Outcome Measure Information:
Title
Change in maximum isometric knee-extension strength and strength deficits, fractured % of non-fractured limb measured by handheld dynamometer.
Time Frame
Baseline to discharge, in average 10 days.
Other Pre-specified Outcome Measures:
Title
Association between 10 meter fast speed walk and knee-extension strength discharge from hospital.
Time Frame
Day before discharge from hospital.

10. Eligibility

Sex
All
Minimum Age & Unit of Time
60 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: Hip fracture diagnosed patients age ≥60 years, admitted to the acute hip fracture unit. Medial femoral neck fracture, pertrochanteric fracture or subtrochanteric fracture. Ability to speak and understand the Danish language. Cognitively well-preserved and able to give personal informed consent no later than by 5th post surgical day. Home-residing and with an independent pre-fracture ability to walk equal to New Mobility Score at ≥ 2 indoor. Exclusion Criteria: Multiple fractures Postsurgical restrictions of mobilization Patient not accepting participation in relevant exercise therapy Fracture caused by cancer metastases Terminal illness Neurological impairment e.g. hemi paresis.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Morten T Kristensen, PhD
Organizational Affiliation
Copenhagen University Hospital at Hvidovre, Denmark
Official's Role
Study Director
Facility Information:
Facility Name
Copenhagen University Hospital, Hvidovre
City
Hvidovre
ZIP/Postal Code
2650
Country
Denmark

12. IPD Sharing Statement

Citations:
PubMed Identifier
24699276
Citation
Kronborg L, Bandholm T, Palm H, Kehlet H, Kristensen MT. Feasibility of progressive strength training implemented in the acute ward after hip fracture surgery. PLoS One. 2014 Apr 3;9(4):e93332. doi: 10.1371/journal.pone.0093332. eCollection 2014.
Results Reference
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Early Strength Training After Hip Fracture Surgery

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