search
Back to results

Musical Dual Task Training to Improve Attention Control for Dementia

Primary Purpose

Dementia

Status
Unknown status
Phase
Not Applicable
Locations
Taiwan
Study Type
Interventional
Intervention
Musical Dual Task Training
Walking and Talking
Sponsored by
Chang Gung Memorial Hospital
About
Eligibility
Locations
Arms
Outcomes
Full info

About this trial

This is an interventional treatment trial for Dementia focused on measuring Musical Dual Task Training, dementia, attention control, dual task cost, gait stability

Eligibility Criteria

55 Years - undefined (Adult, Older Adult)All SexesDoes not accept healthy volunteers

Inclusion Criteria:

  • a mild to moderate dementia diagnosis with Clinical Dementia Rating (CDR) score: .5, 1, or 2
  • ability to walk 10 meters independently without the use of a walker or cane, or the assistance by another person

Exclusion Criteria:

  • other known neurologic disorders such as stroke or Parkinson's disease
  • significant orthopedic, visual, and hearing impairment that hinders ambulation

Sites / Locations

  • Chang Gung Medical FoundationRecruiting

Arms of the Study

Arm 1

Arm 2

Arm Type

Experimental

Active Comparator

Arm Label

Musical Dual Task Training

Walking and Talking

Arm Description

60 minute individual session once a week across 2 months for a total of 8 sessions.Each session will be led by a qualified music therapist. Within the Musical Dual Task Training session, participant will be asked to sing familiar songs, play simple percussive musical instruments such as paddle drums and shakers, sing while walking, and play instruments while walking.

60 minute individual session once a week across 2 months for a total of 8 sessions.Each session will be led by a qualified music therapist. Within the walking and talking session, participant will be asked to read a newspaper article prior to a walk and have a conversation with the music therapist based on the content of the news while walking.

Outcomes

Primary Outcome Measures

Change from Baseline on the Trail Making Test at 2 months
Trail Making Test Part A requires the participants to draw lines to connect a set of 25 circles as fast as possible following the sequential order of numbers (1,2,3…25) while still maintaining accuracy. Trail Making Test Part B is in a same format, but participants are required to alternates between numbers and letters (1, A, 2, B, etc.). The circles in Part B include both numbers (1 - 13) and letters (A - L). Results for both Part A and Part B are reported as the number of seconds required to complete the task. Higher scores indicate greater impairment.

Secondary Outcome Measures

Change from Baseline on Walking Speed during Dual tasking at 2 Months
Change from Baseline on the Timed Up-and-Go test at 2 Months
Change from Baseline on the 7-item Short Falls Efficacy Scale International at 2 Months
Change from Baseline on the Cohen-Mansfield Agitation Inventory scale at 2 months
Change from Baseline on Stride Lengths during Dual Tasking at 2 Months

Full Information

First Posted
October 1, 2012
Last Updated
November 6, 2012
Sponsor
Chang Gung Memorial Hospital
search

1. Study Identification

Unique Protocol Identification Number
NCT01709188
Brief Title
Musical Dual Task Training to Improve Attention Control for Dementia
Official Title
The Effects of Musical Dual Task Training on Attention Control and Associated Gait Stability of Patients With Mild to Moderate Dementia
Study Type
Interventional

2. Study Status

Record Verification Date
October 2012
Overall Recruitment Status
Unknown status
Study Start Date
October 2012 (undefined)
Primary Completion Date
October 2013 (Anticipated)
Study Completion Date
October 2013 (Anticipated)

3. Sponsor/Collaborators

Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Chang Gung Memorial Hospital

4. Oversight

Data Monitoring Committee
Yes

5. Study Description

Brief Summary
The purpose of this project is to determine if the Musical Dual Task Training program improves attention control that influences measures of gait performances under dual tasking, balance, fear of falling, and behavioral disturbance in patients with mild to moderate dementia. This Musical Dual Task Training protocol is structured with musical content and patients are required to do musical tasks including singing and playing instruments contingent on visual or auditory cues while walking. This paradigm is designed to include music making because it involves great demands on attention and memory that might elicit experience-dependent plasticity in the brain. Musical Dual Task Training is proposed to strengthen brain networking for attention control that consequently may improve the gait performances in patients with dementia, as indicated by reducing dual task cost on gait.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Dementia
Keywords
Musical Dual Task Training, dementia, attention control, dual task cost, gait stability

7. Study Design

Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
30 (Anticipated)

8. Arms, Groups, and Interventions

Arm Title
Musical Dual Task Training
Arm Type
Experimental
Arm Description
60 minute individual session once a week across 2 months for a total of 8 sessions.Each session will be led by a qualified music therapist. Within the Musical Dual Task Training session, participant will be asked to sing familiar songs, play simple percussive musical instruments such as paddle drums and shakers, sing while walking, and play instruments while walking.
Arm Title
Walking and Talking
Arm Type
Active Comparator
Arm Description
60 minute individual session once a week across 2 months for a total of 8 sessions.Each session will be led by a qualified music therapist. Within the walking and talking session, participant will be asked to read a newspaper article prior to a walk and have a conversation with the music therapist based on the content of the news while walking.
Intervention Type
Behavioral
Intervention Name(s)
Musical Dual Task Training
Intervention Type
Behavioral
Intervention Name(s)
Walking and Talking
Primary Outcome Measure Information:
Title
Change from Baseline on the Trail Making Test at 2 months
Description
Trail Making Test Part A requires the participants to draw lines to connect a set of 25 circles as fast as possible following the sequential order of numbers (1,2,3…25) while still maintaining accuracy. Trail Making Test Part B is in a same format, but participants are required to alternates between numbers and letters (1, A, 2, B, etc.). The circles in Part B include both numbers (1 - 13) and letters (A - L). Results for both Part A and Part B are reported as the number of seconds required to complete the task. Higher scores indicate greater impairment.
Time Frame
Baseline and at 2 months
Secondary Outcome Measure Information:
Title
Change from Baseline on Walking Speed during Dual tasking at 2 Months
Time Frame
Baseline and at 2 months
Title
Change from Baseline on the Timed Up-and-Go test at 2 Months
Time Frame
Baseline and 2 months
Title
Change from Baseline on the 7-item Short Falls Efficacy Scale International at 2 Months
Time Frame
Baseline and at 2 months
Title
Change from Baseline on the Cohen-Mansfield Agitation Inventory scale at 2 months
Time Frame
Baseline and at 2 months
Title
Change from Baseline on Stride Lengths during Dual Tasking at 2 Months
Time Frame
Baseline and at 2 months

10. Eligibility

Sex
All
Minimum Age & Unit of Time
55 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria: a mild to moderate dementia diagnosis with Clinical Dementia Rating (CDR) score: .5, 1, or 2 ability to walk 10 meters independently without the use of a walker or cane, or the assistance by another person Exclusion Criteria: other known neurologic disorders such as stroke or Parkinson's disease significant orthopedic, visual, and hearing impairment that hinders ambulation
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Yu-Cheng Pei, MD, PhD
Phone
886-3-3281200
Ext
3846
Email
yspeii@gmail.com
First Name & Middle Initial & Last Name or Official Title & Degree
Yu-Ling Chen, MA, MME
Phone
886-922123809
Email
yuling1015@gmail.com
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Yu-Cheng Pei, MD, PhD
Organizational Affiliation
Chang Gung Medical Foundation
Official's Role
Principal Investigator
Facility Information:
Facility Name
Chang Gung Medical Foundation
City
Taoyuan
ZIP/Postal Code
333
Country
Taiwan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Yu-Cheng Pei, MD, PhD
Phone
886-3-3281200
Ext
3846
Email
yspeii@gmail.com
First Name & Middle Initial & Last Name & Degree
Yu-Cheng Pei, MD, PhD

12. IPD Sharing Statement

Learn more about this trial

Musical Dual Task Training to Improve Attention Control for Dementia

We'll reach out to this number within 24 hrs