Eating Peanuts for Health
Primary Purpose
Obesity, Overweight, Hyperlipidemia
Status
Completed
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Consumption of 42 grams of peanuts daily
Sponsored by
About this trial
This is an interventional prevention trial for Obesity focused on measuring Obesity, energy balance, variety, nut intake
Eligibility Criteria
Inclusion Criteria:
- Between 18 and 50 years of age
- Weight stable (< 3 kg weight change within last 3 months)
- Constant habitual activity patterns (no deviation > 1x/wk at 30 min/session within last 3 months)
- Constant habitual diet patterns within last 3 months
- Willingness to eat all test foods (peanuts daily for 12 weeks)
- No allergy to foods provided in the study (peanuts)
- Not a daily peanut or tree nut consumer
- Not planning to change use of medications known to influence appetite or metabolism
- Not diabetic or hypertensive
- No history of gastrointestinal pathology
- Non-smoker for one year or more
Exclusion Criteria:
-
Sites / Locations
- Purdue University
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Arm 5
Arm 6
Arm Type
Experimental
Experimental
Experimental
Experimental
Experimental
Experimental
Arm Label
Consumption of 42 g of salted peanuts
Consumption of 42 g of unsalted peanuts
Consumption of 42 g of spicy peanuts
Consumption of 42 g of honey peanuts
Consumption of 42 g of 3 diff. varieties
Consumption of 42 g of var. of types
Arm Description
Consumption of 42 grams of peanuts daily
Consumption of 42 grams of peanuts daily
Consumption of 42 grams of peanuts daily
Consumption of 42 grams of peanuts daily
Consumption of 42 grams of peanuts daily
Consumption of 42 grams of peanuts daily
Outcomes
Primary Outcome Measures
Change in Weight
Change in Blood Lipids
Change in Blood Pressure
Change in Hedonics of peanut consumption
Participants will rate their liking of the sample each day using a visual analog scale.
Change in Body Composition
Change in Fasting Blood Glucose
Change in Cortisol
Change in Insulin
Change in Pulse
Secondary Outcome Measures
Personality Questionnaires
Flavor attribute liking measures
Compliance
Participants will self-report compliance to study protocol using record sheets.
Appetitive Ratings
Collected on handheld computer
Consumption Parameters
Participants will note if peanuts were eaten as a meal or snack, at what time, and with what other foods daily.
Full Information
NCT ID
NCT01886326
First Posted
June 19, 2013
Last Updated
June 21, 2013
Sponsor
Purdue University
Collaborators
United States Agency for International Development (USAID)
1. Study Identification
Unique Protocol Identification Number
NCT01886326
Brief Title
Eating Peanuts for Health
Official Title
Peanut Consumption and Human Weight Management
Study Type
Interventional
2. Study Status
Record Verification Date
June 2013
Overall Recruitment Status
Completed
Study Start Date
February 2010 (undefined)
Primary Completion Date
May 2012 (Actual)
Study Completion Date
May 2012 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Principal Investigator
Name of the Sponsor
Purdue University
Collaborators
United States Agency for International Development (USAID)
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
Evidence is accumulating that peanut consumption confers health benefits, such as reduction of cardiovascular disease risk and possibly diabetes risk (Jenkins et al., 2008; Mattes et al., 2008). However, peanuts are a high fat, energy dense food and concerns about weight gain are widespread. Although research indicates that other characteristics of peanuts offset these properties, and that peanuts may be incorporated into diets without posing a threat to weight gain (Mattes et al., 2008), concern remains among policymakers, healthcare providers, and consumers. Furthermore, worry exists that eating salted peanuts may elevate blood pressure and that eating honey-roasted peanuts make elevate blood sugar. These fears create substantial obstacles to increased peanut consumption.
Recommendations to increase peanut consumption may be made, but if they are not followed, there will be no impact on health. Additional knowledge is needed on: (1) the acceptability of peanuts consumed on a chronic basis, (2) the chronic intake of moderate levels of peanuts and body weight, and 3) the effects of peanuts on blood pressure and blood sugar. The proposed research will examine the acceptability of long-term inclusion of a single form versus varied forms of peanuts in the diet. It is expected that responses will be varied among individuals with different personality characteristics (e.g., prefer sweet versus savory foods, hedonic versus non-hedonic eaters). A better understanding of how different segments of the population choose to include peanuts in their diet and how to optimize long-term consumption should provide insights for better marketing and improved health. Furthermore, it is anticipated that eating salty peanuts will not raise blood pressure and that eating honey-roasted peanuts will not raise blood sugar. Documenting this will add credibility to the evidence that peanuts do not cause weight gain, as well as reinforce recommendations to increase peanut consumption for their health benefits.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obesity, Overweight, Hyperlipidemia
Keywords
Obesity, energy balance, variety, nut intake
7. Study Design
Primary Purpose
Prevention
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
196 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Consumption of 42 g of salted peanuts
Arm Type
Experimental
Arm Description
Consumption of 42 grams of peanuts daily
Arm Title
Consumption of 42 g of unsalted peanuts
Arm Type
Experimental
Arm Description
Consumption of 42 grams of peanuts daily
Arm Title
Consumption of 42 g of spicy peanuts
Arm Type
Experimental
Arm Description
Consumption of 42 grams of peanuts daily
Arm Title
Consumption of 42 g of honey peanuts
Arm Type
Experimental
Arm Description
Consumption of 42 grams of peanuts daily
Arm Title
Consumption of 42 g of 3 diff. varieties
Arm Type
Experimental
Arm Description
Consumption of 42 grams of peanuts daily
Arm Title
Consumption of 42 g of var. of types
Arm Type
Experimental
Arm Description
Consumption of 42 grams of peanuts daily
Intervention Type
Other
Intervention Name(s)
Consumption of 42 grams of peanuts daily
Intervention Description
Consumption of the given 42 grams of peanuts daily without instructions for use (i.e. with/without meals, etc.)
Primary Outcome Measure Information:
Title
Change in Weight
Time Frame
2, 4, 6, 8, 10, and 12 weeks
Title
Change in Blood Lipids
Time Frame
4, 8, and 12 weeks
Title
Change in Blood Pressure
Time Frame
2, 4, 6, 8, 10, and 12 weeks
Title
Change in Hedonics of peanut consumption
Description
Participants will rate their liking of the sample each day using a visual analog scale.
Time Frame
12 weeks
Title
Change in Body Composition
Time Frame
2, 4, 6, 8, 10, and 12 weeks
Title
Change in Fasting Blood Glucose
Time Frame
4, 8, and 12 weeks
Title
Change in Cortisol
Time Frame
4, 8, and 12 weeks
Title
Change in Insulin
Time Frame
4, 8, and 12 weeks
Title
Change in Pulse
Time Frame
2, 4, 6, 8, 10, and 12 weeks
Secondary Outcome Measure Information:
Title
Personality Questionnaires
Time Frame
At baseline visit
Title
Flavor attribute liking measures
Time Frame
At baseline
Title
Compliance
Description
Participants will self-report compliance to study protocol using record sheets.
Time Frame
12 weeks
Title
Appetitive Ratings
Description
Collected on handheld computer
Time Frame
4, 8, and 12 weeks
Title
Consumption Parameters
Description
Participants will note if peanuts were eaten as a meal or snack, at what time, and with what other foods daily.
Time Frame
12 weeks
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
50 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
Between 18 and 50 years of age
Weight stable (< 3 kg weight change within last 3 months)
Constant habitual activity patterns (no deviation > 1x/wk at 30 min/session within last 3 months)
Constant habitual diet patterns within last 3 months
Willingness to eat all test foods (peanuts daily for 12 weeks)
No allergy to foods provided in the study (peanuts)
Not a daily peanut or tree nut consumer
Not planning to change use of medications known to influence appetite or metabolism
Not diabetic or hypertensive
No history of gastrointestinal pathology
Non-smoker for one year or more
Exclusion Criteria:
-
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Richard D Mattes, RD, MPH, PhD
Organizational Affiliation
Purdue University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Purdue University
City
West Lafayette
State/Province
Indiana
ZIP/Postal Code
47907
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
25064672
Citation
Jones JB, Provost M, Keaver L, Breen C, Ludy MJ, Mattes RD. Effects of daily consumption of one or varied peanut flavors on acceptance and intake. Appetite. 2014 Nov;82:208-12. doi: 10.1016/j.appet.2014.07.023. Epub 2014 Jul 23.
Results Reference
derived
PubMed Identifier
24351876
Citation
Jones JB, Provost M, Keaver L, Breen C, Ludy MJ, Mattes RD. A randomized trial on the effects of flavorings on the health benefits of daily peanut consumption. Am J Clin Nutr. 2014 Mar;99(3):490-6. doi: 10.3945/ajcn.113.069401. Epub 2013 Dec 18.
Results Reference
derived
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Eating Peanuts for Health
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