HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial (HIP ATTACK)
Primary Purpose
Hip Fractures
Status
Active
Phase
Not Applicable
Locations
International
Study Type
Interventional
Intervention
Accelerated medical clearance and surgery
Sponsored by
About this trial
This is an interventional treatment trial for Hip Fractures focused on measuring Perioperative outcomes
Eligibility Criteria
Inclusion Criteria:
- age ≥45 years; and
- diagnosis of hip fracture during working hours with a low-energy mechanism (i.e., falling from standing height) requiring surgery.
Exclusion Criteria:
- patients requiring emergent surgery or emergent interventions for another reason (e.g., subdural hematoma, abdominal pathology requiring urgent laparotomy, acute limb ischemia, other fractures or trauma requiring emergent surgery, necrotising fasciitis, coronary revascularization, pacemaker-implantation);
- open hip fracture;
- bilateral hip fractures;
- peri-prosthetic fracture;
- therapeutic anticoagulation not induced by a Vitamin K Antagonist, unfractionated heparin, (e.g., administration of therapeutic Low Molecular Weight Heparin (LMWH) (>6,000 u/24h) in the 24 hours prior to enrolment, or intake of any other non-reversible oral anticoagulant(s) for which there is no reversing agent available
- patients on a therapeutic vitamin K antagonist with a history of heparin induced thrombocytopenia (HIT);
- patients refusing participation; or
- patients previously enrolled in the study.
Sites / Locations
- Regional Medical Center of San Jose
- University of Maryland
- Lahey Hospital and Medical Centre
- Tufts Medical Centre
- Ohio State University Medical Centre
- Cliniques Universitaires Saint-Luc
- Cliniques Universitaires Saint-Luc
- South Health Campus
- University of Alberta Hospital
- Vancouver General Hospital
- Concordia Hip and Knee Institute
- QEII Health Sciences
- Royal Victoria Hospital
- Etobicoke General Hospital
- St. Joseph's Hospital Hamilton
- Hamilton Health Sciences - Juravinski Hospital
- Kingston General Hospital
- Grand River Hospital
- Victoria Hospital, London Health Sciences
- Markham Stouffville Hospital
- Ottawa General Hospital
- Thunder Bay Regional Health Sciences Centre
- Humber River Hospital
- St. Michael's Hospital
- Sunnybrook Health Sciences Centre
- Beijing Chaoyang Hospital
- Fundacion Cardioinfantil
- Centre Hospitalier Lyon Sud
- Nimes University Hospital
- Queen Mary Hospital
- Government TD Medical College
- Sparsh Hospital
- PGIMER
- Bangalore Baptist Hospital
- NH Kolkata
- CMC Ludhiana
- Seven Star Hospital
- AIIMS Hospital
- JIPMER
- Sancheti Institute for Orthopaedics and Rehabilitation
- Government Medical Hospital
- Ospedale San Raffaele
- Humanitas Research Hospital
- IRCCS Galeazzi Orthopedic Institute
- ASST Sette Laghi - Ospedale Di
- Hospital Pulau Pinang
- University Malaya Medical Centre (UMMC)
- Deventer Ziekenhuis
- Shifa International Hospitals
- The Aga Khan University
- SPZOZ Szpital Powiatowy w Bochni im M. Wieckiej
- Samodzielny Publiczny Zakład Opieki Zdrowotnej W Myślenicach
- University Hospital & Educational Center of Medical University in Lodz
- Groote Schuur Hospital
- Stellenbosch University
- Chris Hani Baragwanath Hospital
- Hospital San Pau
- Hospital Universitaire Vall d'Hebron
- Corporació Sanitària Parc Taulí
- Mutua de Terrassa Hospital
- Hospital Sant Camil (Consorci Sanitari Garraf)
- Costa del Sol
- Hospital Clinico Universitario de Vallad
- Ramathibodi Hospital
- Calderdale & Huddersfield NHS
- Chelsea and Westminster Hospital
- West Middlesex Hospital
- Peterborough City Hospital
- King's Mill Hospital
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
No Intervention
Arm Label
Accelerated medical clearance and surgery
Standard surgical care
Arm Description
Rapid medical clearance with targeted arrival to the operating room within 6 hours of diagnosis of a hip fracture requiring surgical repair.
Surgical hip fracture repair according to the standard timing.
Outcomes
Primary Outcome Measures
Composite - major perioperative complication
Composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding
Mortality
All-cause mortality
Secondary Outcome Measures
All-cause mortality
Death due to all causes
Vascular mortality
Death due to vascular cause
Non-vascular mortality
Death due to non-vascular cause
Myocardial infarction
Myocardial infarction
Cardiac revascularization procedure
i.e., percutaneous coronary intervention [PCI] or coronary artery bypass grafting [CABG] surgery
New congestive heart failure
New congestive heart failure
New clinically important atrial fibrillation
New clinically important atrial fibrillation
Nonfatal cardiac arrest
Nonfatal cardiac arrest
Stroke
Stroke
Peripheral arterial thrombosis
Peripheral arterial thrombosis
Pulmonary embolism
Pulmonary embolism
Deep venous thrombosis
Deep venous thrombosis
Pneumonia
Pneumonia
Sepsis
Sepsis
Infection
Infection
Life-threatening bleeding
Life-threatening bleeding
Major bleeding
Major bleeding
New acute renal failure requiring dialysis
New acute renal failure requiring dialysis
Peri-prosthetic fracture
Peri-prosthetic fracture
Prosthetic hip dislocation
Prosthetic hip dislocation
Implant failure
Implant failure
Hip re-operation
Hip re-operation
Time to first mobilization
Time to first mobilization
Length of hospital stay
Length of hospital stay
Length of critical care stay
Length of critical care stay
Length of rehabilitation stay
Length of rehabilitation stay
New residence in a nursing home
New residence in a nursing home
Functional Independence Measure (FIM™)
Functional Independence Measure (FIM™)
SF-36 score
SF-36 score
Delirium within 7 days of randomization
Delirium within 7 days of randomization
Hospital readmission
Hospital readmission
New pressure ulcers
New pressure ulcers
Incisional pain
Incisional pain
Chronic incisional pain
Chronic incisional pain
Acute Kidney Injury
Acute Kidney Injury
Acute Kidney Injury
Acute Kidney Injury
Mortality and Institutionalization status of dependents
Mortality and Institutionalization status of dependents
Mortality and Institutionalization status of dependents
Mortality and Institutionalization status of dependents
Economic Analysis
Economic Analysis
Health System Utilization, Long Term Follow up
Health System Utilization, Long Term Follow up
Full Information
NCT ID
NCT02027896
First Posted
January 2, 2014
Last Updated
August 23, 2022
Sponsor
McMaster University
Collaborators
Population Health Research Institute, Hamilton Health Sciences Corporation
1. Study Identification
Unique Protocol Identification Number
NCT02027896
Brief Title
HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial
Acronym
HIP ATTACK
Official Title
HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial
Study Type
Interventional
2. Study Status
Record Verification Date
August 2022
Overall Recruitment Status
Active, not recruiting
Study Start Date
March 2014 (undefined)
Primary Completion Date
August 24, 2019 (Actual)
Study Completion Date
September 24, 2022 (Anticipated)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
McMaster University
Collaborators
Population Health Research Institute, Hamilton Health Sciences Corporation
4. Oversight
Data Monitoring Committee
Yes
5. Study Description
Brief Summary
HIP ATTACK is an international randomized controlled trial of 3000 patients with a hip fracture that requires a surgical intervention. This trial will determine the effect of accelerated medical clearance and accelerated surgery compared to standard care on the 90-day risk of mortality and major perioperative complication (i.e., a composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding).
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Hip Fractures
Keywords
Perioperative outcomes
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
Outcomes Assessor
Allocation
Randomized
Enrollment
3001 (Actual)
8. Arms, Groups, and Interventions
Arm Title
Accelerated medical clearance and surgery
Arm Type
Experimental
Arm Description
Rapid medical clearance with targeted arrival to the operating room within 6 hours of diagnosis of a hip fracture requiring surgical repair.
Arm Title
Standard surgical care
Arm Type
No Intervention
Arm Description
Surgical hip fracture repair according to the standard timing.
Intervention Type
Other
Intervention Name(s)
Accelerated medical clearance and surgery
Intervention Description
Rapid medical clearance with targeted arrival to the operating room within 6 hours of diagnosis of a hip fracture requiring surgical repair.
Primary Outcome Measure Information:
Title
Composite - major perioperative complication
Description
Composite of mortality, nonfatal myocardial infarction, nonfatal pulmonary embolism, nonfatal pneumonia, nonfatal sepsis, nonfatal stroke, and nonfatal life-threatening and major bleeding
Time Frame
90 days
Title
Mortality
Description
All-cause mortality
Time Frame
90 days
Secondary Outcome Measure Information:
Title
All-cause mortality
Description
Death due to all causes
Time Frame
90 days and 1 year
Title
Vascular mortality
Description
Death due to vascular cause
Time Frame
90 days and 1 year
Title
Non-vascular mortality
Description
Death due to non-vascular cause
Time Frame
90 days and 1 year
Title
Myocardial infarction
Description
Myocardial infarction
Time Frame
90 days and 1 year
Title
Cardiac revascularization procedure
Description
i.e., percutaneous coronary intervention [PCI] or coronary artery bypass grafting [CABG] surgery
Time Frame
90 days and 1 year
Title
New congestive heart failure
Description
New congestive heart failure
Time Frame
90 days and 1 year
Title
New clinically important atrial fibrillation
Description
New clinically important atrial fibrillation
Time Frame
90 days
Title
Nonfatal cardiac arrest
Description
Nonfatal cardiac arrest
Time Frame
30 days and 1 year
Title
Stroke
Description
Stroke
Time Frame
90 days and 1 year
Title
Peripheral arterial thrombosis
Description
Peripheral arterial thrombosis
Time Frame
90 days and 1 year
Title
Pulmonary embolism
Description
Pulmonary embolism
Time Frame
90 days and 1 year
Title
Deep venous thrombosis
Description
Deep venous thrombosis
Time Frame
90 days and 1 year
Title
Pneumonia
Description
Pneumonia
Time Frame
90 days and 1 year
Title
Sepsis
Description
Sepsis
Time Frame
90 days and 1 year
Title
Infection
Description
Infection
Time Frame
90 days
Title
Life-threatening bleeding
Description
Life-threatening bleeding
Time Frame
90 days
Title
Major bleeding
Description
Major bleeding
Time Frame
90 days
Title
New acute renal failure requiring dialysis
Description
New acute renal failure requiring dialysis
Time Frame
90 days and 1 year
Title
Peri-prosthetic fracture
Description
Peri-prosthetic fracture
Time Frame
90 days and 1 year
Title
Prosthetic hip dislocation
Description
Prosthetic hip dislocation
Time Frame
90 days and 1 year
Title
Implant failure
Description
Implant failure
Time Frame
90 days and 1 year
Title
Hip re-operation
Description
Hip re-operation
Time Frame
30 days and 1 year
Title
Time to first mobilization
Description
Time to first mobilization
Time Frame
90 days
Title
Length of hospital stay
Description
Length of hospital stay
Time Frame
90 days
Title
Length of critical care stay
Description
Length of critical care stay
Time Frame
90 days
Title
Length of rehabilitation stay
Description
Length of rehabilitation stay
Time Frame
90 days
Title
New residence in a nursing home
Description
New residence in a nursing home
Time Frame
90 days and 1 year
Title
Functional Independence Measure (FIM™)
Description
Functional Independence Measure (FIM™)
Time Frame
30 days and 1 year
Title
SF-36 score
Description
SF-36 score
Time Frame
30 days and 1 year
Title
Delirium within 7 days of randomization
Description
Delirium within 7 days of randomization
Time Frame
7 days
Title
Hospital readmission
Description
Hospital readmission
Time Frame
90 days and 1 year
Title
New pressure ulcers
Description
New pressure ulcers
Time Frame
90 days
Title
Incisional pain
Description
Incisional pain
Time Frame
30 days
Title
Chronic incisional pain
Description
Chronic incisional pain
Time Frame
1 year
Title
Acute Kidney Injury
Description
Acute Kidney Injury
Time Frame
90 Day
Title
Acute Kidney Injury
Description
Acute Kidney Injury
Time Frame
1 Year
Title
Mortality and Institutionalization status of dependents
Description
Mortality and Institutionalization status of dependents
Time Frame
30 Days
Title
Mortality and Institutionalization status of dependents
Description
Mortality and Institutionalization status of dependents
Time Frame
1 Year
Title
Economic Analysis
Description
Economic Analysis
Time Frame
90 Days and 1 Year
Title
Health System Utilization, Long Term Follow up
Description
Health System Utilization, Long Term Follow up
Time Frame
2, 5, 10 Years
10. Eligibility
Sex
All
Minimum Age & Unit of Time
45 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
age ≥45 years; and
diagnosis of hip fracture during working hours with a low-energy mechanism (i.e., falling from standing height) requiring surgery.
Exclusion Criteria:
patients requiring emergent surgery or emergent interventions for another reason (e.g., subdural hematoma, abdominal pathology requiring urgent laparotomy, acute limb ischemia, other fractures or trauma requiring emergent surgery, necrotising fasciitis, coronary revascularization, pacemaker-implantation);
open hip fracture;
bilateral hip fractures;
peri-prosthetic fracture;
therapeutic anticoagulation not induced by a Vitamin K Antagonist, unfractionated heparin, (e.g., administration of therapeutic Low Molecular Weight Heparin (LMWH) (>6,000 u/24h) in the 24 hours prior to enrolment, or intake of any other non-reversible oral anticoagulant(s) for which there is no reversing agent available
patients on a therapeutic vitamin K antagonist with a history of heparin induced thrombocytopenia (HIT);
patients refusing participation; or
patients previously enrolled in the study.
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Philip J Devereaux, MD, PhD
Organizational Affiliation
McMaster University
Official's Role
Principal Investigator
First Name & Middle Initial & Last Name & Degree
Mohit Bhandari, MD, PhD
Organizational Affiliation
McMaster University
Official's Role
Principal Investigator
Facility Information:
Facility Name
Regional Medical Center of San Jose
City
San Jose
State/Province
California
Country
United States
Facility Name
University of Maryland
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
20742
Country
United States
Facility Name
Lahey Hospital and Medical Centre
City
Burlington
State/Province
Massachusetts
ZIP/Postal Code
01805
Country
United States
Facility Name
Tufts Medical Centre
City
Washington
State/Province
Massachusetts
ZIP/Postal Code
02111
Country
United States
Facility Name
Ohio State University Medical Centre
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43210
Country
United States
Facility Name
Cliniques Universitaires Saint-Luc
City
Brussels
Country
Belgium
Facility Name
Cliniques Universitaires Saint-Luc
City
Woluwe-Saint-Lambert
Country
Belgium
Facility Name
South Health Campus
City
Calgary
State/Province
Alberta
Country
Canada
Facility Name
University of Alberta Hospital
City
Edmonton
State/Province
Alberta
Country
Canada
Facility Name
Vancouver General Hospital
City
Vancouver
State/Province
British Columbia
Country
Canada
Facility Name
Concordia Hip and Knee Institute
City
Winnipeg,
State/Province
Manitoba
ZIP/Postal Code
MB R2K 2M9
Country
Canada
Facility Name
QEII Health Sciences
City
Halifax,
State/Province
Nova Scotia
ZIP/Postal Code
B3H 3A7
Country
Canada
Facility Name
Royal Victoria Hospital
City
Barrie
State/Province
Ontario
Country
Canada
Facility Name
Etobicoke General Hospital
City
Etobicoke
State/Province
Ontario
Country
Canada
Facility Name
St. Joseph's Hospital Hamilton
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8N 4A6
Country
Canada
Facility Name
Hamilton Health Sciences - Juravinski Hospital
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8V 5C2
Country
Canada
Facility Name
Kingston General Hospital
City
Kingston
State/Province
Ontario
ZIP/Postal Code
K7L 2V7
Country
Canada
Facility Name
Grand River Hospital
City
Kitchener
State/Province
Ontario
Country
Canada
Facility Name
Victoria Hospital, London Health Sciences
City
London
State/Province
Ontario
Country
Canada
Facility Name
Markham Stouffville Hospital
City
Markham
State/Province
Ontario
Country
Canada
Facility Name
Ottawa General Hospital
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1H 8L6
Country
Canada
Facility Name
Thunder Bay Regional Health Sciences Centre
City
Thunder Bay
State/Province
Ontario
ZIP/Postal Code
P7B 6V4
Country
Canada
Facility Name
Humber River Hospital
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M3M 0B2
Country
Canada
Facility Name
St. Michael's Hospital
City
Toronto
State/Province
Ontario
Country
Canada
Facility Name
Sunnybrook Health Sciences Centre
City
Toronto
State/Province
Ontario
Country
Canada
Facility Name
Beijing Chaoyang Hospital
City
Beijing
Country
China
Facility Name
Fundacion Cardioinfantil
City
Bogotá
ZIP/Postal Code
13B-60
Country
Colombia
Facility Name
Centre Hospitalier Lyon Sud
City
Lyon
Country
France
Facility Name
Nimes University Hospital
City
Nîmes Cedex 09
ZIP/Postal Code
30029
Country
France
Facility Name
Queen Mary Hospital
City
High West
Country
Hong Kong
Facility Name
Government TD Medical College
City
Alappuzha
ZIP/Postal Code
688005
Country
India
Facility Name
Sparsh Hospital
City
Bangalore
ZIP/Postal Code
560099
Country
India
Facility Name
PGIMER
City
Chandigarh
Country
India
Facility Name
Bangalore Baptist Hospital
City
Hebbal
ZIP/Postal Code
560024
Country
India
Facility Name
NH Kolkata
City
Kolkata
ZIP/Postal Code
700099
Country
India
Facility Name
CMC Ludhiana
City
Ludhiana
ZIP/Postal Code
141008
Country
India
Facility Name
Seven Star Hospital
City
Nagpur
Country
India
Facility Name
AIIMS Hospital
City
New Delhi
Country
India
Facility Name
JIPMER
City
Puducherry
Country
India
Facility Name
Sancheti Institute for Orthopaedics and Rehabilitation
City
Shivajinagar
ZIP/Postal Code
411005
Country
India
Facility Name
Government Medical Hospital
City
Trivandrum
Country
India
Facility Name
Ospedale San Raffaele
City
Milan
ZIP/Postal Code
20132
Country
Italy
Facility Name
Humanitas Research Hospital
City
Milan
Country
Italy
Facility Name
IRCCS Galeazzi Orthopedic Institute
City
Milan
Country
Italy
Facility Name
ASST Sette Laghi - Ospedale Di
City
Varese
Country
Italy
Facility Name
Hospital Pulau Pinang
City
George Town
Country
Malaysia
Facility Name
University Malaya Medical Centre (UMMC)
City
Kuala Lumpur
ZIP/Postal Code
59100
Country
Malaysia
Facility Name
Deventer Ziekenhuis
City
Deventer
Country
Netherlands
Facility Name
Shifa International Hospitals
City
Islāmābād
ZIP/Postal Code
44000
Country
Pakistan
Facility Name
The Aga Khan University
City
Karachi
ZIP/Postal Code
74800
Country
Pakistan
Facility Name
SPZOZ Szpital Powiatowy w Bochni im M. Wieckiej
City
Bochnia
Country
Poland
Facility Name
Samodzielny Publiczny Zakład Opieki Zdrowotnej W Myślenicach
City
Myślenice
ZIP/Postal Code
32-400
Country
Poland
Facility Name
University Hospital & Educational Center of Medical University in Lodz
City
Łódź
Country
Poland
Facility Name
Groote Schuur Hospital
City
Cape Town
ZIP/Postal Code
7925
Country
South Africa
Facility Name
Stellenbosch University
City
Cape Town
Country
South Africa
Facility Name
Chris Hani Baragwanath Hospital
City
Johannesburg
ZIP/Postal Code
2193
Country
South Africa
Facility Name
Hospital San Pau
City
Barcelona
ZIP/Postal Code
08025
Country
Spain
Facility Name
Hospital Universitaire Vall d'Hebron
City
Barcelona
ZIP/Postal Code
08035
Country
Spain
Facility Name
Corporació Sanitària Parc Taulí
City
Barcelona
ZIP/Postal Code
08208
Country
Spain
Facility Name
Mutua de Terrassa Hospital
City
Barcelona
ZIP/Postal Code
08221
Country
Spain
Facility Name
Hospital Sant Camil (Consorci Sanitari Garraf)
City
Barcelona
Country
Spain
Facility Name
Costa del Sol
City
Marbella
ZIP/Postal Code
29603
Country
Spain
Facility Name
Hospital Clinico Universitario de Vallad
City
Valladolid
Country
Spain
Facility Name
Ramathibodi Hospital
City
Bangkok,
ZIP/Postal Code
10400
Country
Thailand
Facility Name
Calderdale & Huddersfield NHS
City
Huddersfield
Country
United Kingdom
Facility Name
Chelsea and Westminster Hospital
City
London
ZIP/Postal Code
SW10 9NH
Country
United Kingdom
Facility Name
West Middlesex Hospital
City
London
Country
United Kingdom
Facility Name
Peterborough City Hospital
City
Peterborough
Country
United Kingdom
Facility Name
King's Mill Hospital
City
Sutton in Ashfield
ZIP/Postal Code
NG17 4JL
Country
United Kingdom
12. IPD Sharing Statement
Citations:
PubMed Identifier
32050090
Citation
HIP ATTACK Investigators. Accelerated surgery versus standard care in hip fracture (HIP ATTACK): an international, randomised, controlled trial. Lancet. 2020 Feb 29;395(10225):698-708. doi: 10.1016/S0140-6736(20)30058-1. Epub 2020 Feb 9. Erratum In: Lancet. 2021 Nov 27;398(10315):1964. Lancet. 2023 Apr 1;401(10382):1078.
Results Reference
derived
PubMed Identifier
31551393
Citation
Borges FK, Devereaux PJ, Cuerden M, Bhandari M, Guerra-Farfan E, Patel A, Sigamani A, Umer M, Neary J, Tiboni M, Tandon V, Ramokgopa MT, Sancheti P, John B, Lawendy A, Balaguer-Castro M, Jenkinson R, Sleczka P, Nabi Nur A, Wood GCA, Feibel R, McMahon JS, Sigamani A, Biccard BM, Landoni G, Szczeklik W, Wang CY, Tomas-Hernandez J, Abraham V, Vincent J, Harvey V, Pettit S, Sontrop J, Garg AX; HIP ATTACK investigators. Effects of accelerated versus standard care surgery on the risk of acute kidney injury in patients with a hip fracture: a substudy protocol of the hip fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) international randomised controlled trial. BMJ Open. 2019 Sep 24;9(9):e033150. doi: 10.1136/bmjopen-2019-033150.
Results Reference
derived
PubMed Identifier
31048449
Citation
Borges FK, Bhandari M, Patel A, Avram V, Guerra-Farfan E, Sigamani A, Umer M, Tiboni M, Adili A, Neary J, Tandon V, Sancheti PK, Lawendy A, Jenkinson R, Ramokgopa M, Biccard BM, Szczeklik W, Wang CY, Landoni G, Forget P, Popova E, Wood G, Nabi Nur A, John B, Sleczka P, Feibel RJ, Balaguer-Castro M, Deheshi B, Winemaker M, de Beer J, Kolesar R, Teixidor-Serra J, Tomas-Hernandez J, McGillion M, Shanthanna H, Moppett I, Vincent J, Pettit S, Harvey V, Gauthier L, Alvarado K, Devereaux PJ. Rationale and design of the HIP fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) Trial: a protocol for an international randomised controlled trial evaluating early surgery for hip fracture patients. BMJ Open. 2019 May 1;9(4):e028537. doi: 10.1136/bmjopen-2018-028537.
Results Reference
derived
Links:
URL
http://www.cmaj.ca/content/early/2013/11/18/cmaj.130901
Description
HIP ATTACK Pilot Canadian Medical Association Journal (CMAJ) Publication
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HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial
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