Impedance vs. Contact Force Guided Atrial Fibrillation Ablation Using Automated Annotation System
Atrial Fibrillation
About this trial
This is an interventional treatment trial for Atrial Fibrillation focused on measuring Atrial Fibrillation, Catheter ablation
Eligibility Criteria
Inclusion Criteria:
- Patients with non-valvular atrial fibrillation
- Patients having atrial fibrillation even after receiving continued treatment with at least 1 antiarrhythmic drug for more than 6 weeks
- Patients with tachycardia-bradycardia syndrome associated with atrial fibrillation.
- Patients who can understand the information sheet and consent form on the need and procedure of catheter ablation and submitted them
- Patients who are available of follow-up at least for more than three months after catheter ablation
Exclusion Criteria:
- Patients unsuitable for catheter ablation because the size of left atrium is over 5.5cm
- Patients unsuitable for catheter ablation due to previous history of pulmonary surgery or structural heat disease.
- Patients who cannot receive standard treatments such as anticoagulation therapy which need to be continuously performed prior to radiofrequency catheter ablation
- Patients in the subject group vulnerable to clinical study
- Patients who had undergone a prior catheter ablation for atrial fibrillation
Sites / Locations
- Keimyung University Dongsan Medical Center
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Impedance Guided Ablation Group
Contact Forced Guided Ablation Group
Impedance guided ablation group performs pulmonary vein(PV) isolation guided by annotation criteria with minimum time of 10 seconds, maximum range of 2 mm, and minimum impedance decrease over 5 Ohms instead of CF parameters. In the impedance guided group, operators are blinded to contact force data during PV isolation.
Contact force(CF) guided ablation group performs pulmonary vein (PV) isolation guided by automated annotation criteria with minimum time of 10 seconds, maximum range of 2mm, CF over time of 50% and minimum CF of 10 g.