An Evidence Based Protocol for Oxytocin Administration in Vaginal Delivery
Uterine Atony, Postpartum Hemorrhage
About this trial
This is an interventional treatment trial for Uterine Atony focused on measuring Uterine atony, Postpartum hemorrhage, Vaginal delivery, Uterotonic, Oxytocin, Bolus, Evidence-based, Protocol
Eligibility Criteria
Inclusion Criteria:
- Vaginal Delivery
Exclusion Criteria:
- Cesarean Delivery
- Allergy to Oxytocin
- Cardiac Arrhythmia
Sites / Locations
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Conventional standard of care
Evidence based protocol
Traditional administration of oxytocin at Lutheran Medical Center involves the use of two 20 IU / 1000 mL bags hung sequentially at a flow rate of 125 mL / hour each after the delivery of the anterior shoulder. This will total no more than 16 hours.
The proposed evidence based protocol involves utilizing a single 30IU / 500mL bag of oxytocin. After the delivery of the anterior shoulder, an initial rapid infusion bolus of 50mL of the 30IU / 500mL at 999mL / hour. Three minutes after rapid infusion, uterine tone should be assessed. If inadequate uterine tone persists, a second rapid infusion at the same dose and rate as above should be given. If inadequate uterine tone persists, a third rapid infusion may be given. If adequate uterine tone is achieved after any rapid infusion, the remainder of the bag should be administered at a rate of 100mL / hour until finished. If adequate tone is not achieved, the remainder of the bag should be administered at 100mL / hour and additional uterotonic agents should be considered.