The Role of Chromoendoscopy in the Early Detection of Esophageal Cancer in Patients With Prior Head and Neck Cancers
Esophageal Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Head and Neck
About this trial
This is an interventional screening trial for Esophageal Squamous Cell Carcinoma focused on measuring endoscopy, gastrointestinal, cancer screening
Eligibility Criteria
Inclusion Criteria:
- Patients with past history ( >= 1 year ) of head and neck cancer treated curatively and receiving regular follow - up at the outpatient clinic of the Head and Neck Department of Maria Skłodowska - Curie Memorial Cancer Center, Institiut of Oncology
- 18 years and older
- Diagnosis of squamous cell carcinoma of oral cavity, oropharynx, hypopharynx, larynx
- Zubrod scale 0-2
- Provided written informed consent
Exclusion Criteria:
- Lack of written informed consent
- Known allergy to iodine
- Clinical conditions precluding upper GI endoscopy
Sites / Locations
- Maria Sklodowska-curie Memorial Cancer Center, Institiute of Oncology
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
NBI endoscopy
lugol chromoendoscopy
GI endoscopy examination and additional the entire length of esophagus is evaluate with NBI endoscopy Biopsy at the visually abnormal lesions Pathologic examination of all biopsy tissue specimens Advises of endoscopic/surgical or oncological treatment will be given to participants who will be diagnosed with ESCC or high grade dysplasia of the esophagus.
GI endoscopy examination and additional the entire length of esophagus is evaluate with Lugol chromoendoscopy Biopsy at the unstained lesions >= 5 mm diameter Pathologic examination of all biopsy tissue specimens Advises of endoscopic/surgical or oncological treatment will be given to participants who will be diagnosed with ESCC or high grade dysplasia of the esophagus.