Retroperitoneal Packing or Angioembolization for Hemorrhage Control of Pelvic Fractures
Shock, Hemorrhagic, Fractures, Bone, Multiple Trauma
About this trial
This is an interventional treatment trial for Shock, Hemorrhagic
Eligibility Criteria
Inclusion Criteria:
- multitrauma defined as Injury Severity Score (ISS) > 17
- dislocated pelvic fracture type B or C according to Tile[10] on emergency department pelvic radiograph
- hemodynamic instability defined as systolic blood pressure (SBP) <90 mmHg after administration of 4 units of packed red blood cells (PRBC).
Exclusion Criteria:
- monotrauma, or ISS ≤ 17
- age > 65 years
- age < 18 years
Sites / Locations
- Shandong Provincial Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
ANGIO
PACKING
Patients with persistent hemodynamic instability (systolic blood pressure (SBP) <90 mmHg after the transfusion of 4 packed red blood cell (PRBC) units in the emergency department) were taken urgently to the angiography suite for pelvic angiography. These patients had to tolerate transfer to the suite. Patients receiving primarily angioembolization therapy were defined as the ANGIO group.
Indication for pelvic packing was persistent SBP<90 mmHg during the initial resuscitation period with 3000 ml of intravenous (IV) crystalloids and transfusion of 4 PRBC units. These patients were treated primarly with retroperitoneal packing, while angioembolization OR staff was unavailable (5pm-7am), and were defined as the PACK group.