The Use of Microneedles to Expedite Treatment Time in Photodynamic Therapy
Keratosis, Actinic
About this trial
This is an interventional treatment trial for Keratosis, Actinic
Eligibility Criteria
Inclusion Criteria:
- 18 years of age and older
- Subjects has actinic keratoses and qualifies for photodynamic therapy
- Do not meet any of the exclusion criteria
Exclusion Criteria:
- Subjects who smoke
- Subjects who have a photosensitizing condition such as lupus, porphyria, or similar condition
- Subjects who have established allergy to topical ALA
- Subjects who have had a documented nonmelanoma skin cancer on the face over the past 6 months
Sites / Locations
- University of California-Davis, Department of Dermatology
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
10-minute Incubation with Microneedle Roller & Sham
20-minute Incubation with Microneedle Roller & Sham
10-minute topical aminolevulinic acid incubation group. Subjects randomized by binary randomization into each treatment group and undergo secondary binary randomization for microneedle roller treatment (vs. sham microneedle) to the right or left side of the face. Blue light therapy follows.
20-minute topical aminolevulinic acid incubation group. Subjects randomized by binary randomization into each treatment group and undergo secondary binary randomization for microneedle roller treatment (vs. sham microneedle) to the right or left side of the face. Blue light therapy follows.