Uncut Roux-en-y Anastomosis Reduce Postoperative Complication and Improve Nutritional Status After Distal Gastrectomy
Nutrition Disorders, Postoperative Complications
About this trial
This is an interventional prevention trial for Nutrition Disorders focused on measuring Uncut Roux-en-Y, Billroth II anastomosis, Distal gastric cancer, Nutrition status, Postoperative complications
Eligibility Criteria
Inclusion Criteria:
- pathological diagnosed as the gastric carcinoma, the possibility of removal by the surgeon and imaging physician assessment.
- no previous history of other malignancies combined.
- patients have signed informed consent;
- aged 18 to 80 years old, male or female patients;
- cardiopulmonary, liver and kidney function was normal, ECOG physical status score of 0 to 1 (see Appendix);
- the clinician determine the patient does not need emergency surgery;
Exclusion Criteria:
- pregnant or lactating women;
- the liver, lung, bone, and other distant metastasis;
- supraclavicular lymph nodes, pelvic or ovarian species, peritoneal dissemination, etc;
- a large number of ascites, cachexia;
- suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, poorly controlled hypertension merger, diabetes patients;
- or mental illness;
- 4 weeks prior to enrollment participated or are participating in other clinical trials of patients;
- had undergone surgery, and its influence has not been eliminated in the patient;
- of the stomach or esophagus history of malignancy, including stromal tumor, sarcoma, lymphoma, carcinoid;
- patients with active infection (infection causing fever above 38 ℃);
- patients with poor compliance or researchers consider poor patient compliance;
- There are other clinical researchers believe that the laboratory the patient should not participate in the trial.
Sites / Locations
- The sixth affliated hospital of Sun Yat-sen UniversityRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Sham Comparator
uncut Roux-en-Y anastomosis
Billroth II anastomosis
After distal gastrectomy, duodenal stump closure, side to side anastomosis was underwent on the remnant stomach and jejunum,which was 25cm from Treitz ligament. Then underwent side to side anastomosis between jejunum about 35cm distance from gastrojejunostomy and jejunum about 5cm from Triez ligament . close the intestinal cavity on the input less than 5cm distance from the loop gastrojejunostomy anastomosis by using uncut Closure devices
After distal gastrectomy, duodenal stump closure, the investigators first underwent remnant stomach and upper jejunum side anastomosis. Then choose the jejunum about 25cm from Treitz ligament, premenstrual colon using a disposable cutting closure (or tubular stapling) in the rear wall of the stomach and jejunum anastomosis, common opening was closed with the (barbed wire) hand-stitched. After that, steps were same with the group A.