Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using PRF
Periapical Periodontitis, Tooth Diseases, Stomatognathic Diseases
About this trial
This is an interventional treatment trial for Periapical Periodontitis focused on measuring regenerative endodontic treatment, platelet-rich fibrin, Immature permanent tooth, apical periodontitis
Eligibility Criteria
Inclusion Criteria:
- Between 6 and 18 years of age
- Provision of Informed Consent
- Cooperative in the dental chair
- Permanent immature teeth with apical periodontitis and incomplete root development
Exclusion Criteria:
- Have a medical history that may complicate treatment
- Unlikely to be able to comply with the study procedures
Sites / Locations
- School and Hospital of Stomatology, Fujian Medical University
Arms of the Study
Arm 1
Arm 2
Experimental
No Intervention
Regenerative Endodontic Procedure + PRF
Regenerative Endodontic Procedure
Visit 1: root canal dressing with triple antibiotic paste. Visit 2: a 5 ml sample of whole blood was drawn intravenously from the patient's forearm. The blood sample is centrifuged at 400 g for 10 min. The prepared PRF membrane is cut into segments, the fragments are placed into the canal space. The coronal is sealed mineral trioxide aggregate and composite resin.
Regenerative Endodontic Procedure Visit 1: root canal dressing with triple antibiotic paste. Visit 2: Blood clot formation is induced in the root canal after disinfection. No PRF was used in this group. Then the canal access is sealed with mineral trioxide aggregate and composite resin.