Effectiveness Comparison of Skin Micro-grafts vs Meshed Split Thickness Skin Grafts
Skin Ulcer, Burns
About this trial
This is an interventional treatment trial for Skin Ulcer focused on measuring skin transplantation, grafting skin
Eligibility Criteria
Inclusion Criteria:
- Non complicated wounds (no infection, no cancer)
- Wound area: 20 x 20 cms or less
- Located in diverse anatomical regions (except axillar, groin, genital, sole, scalp and flexion or extension areas)
Exclusion Criteria:
- High cardiovascular risk
- Patients with indication of a different technique
Sites / Locations
- "La Raza" Medical Center. IMSSRecruiting
Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
Standard skin graft
Skin micro graft
This group is comprised of patients' wound halves that will receive meshed (1:3) split thickness skin graft (0.3-0.5mm thickness). This half will be covered with a standard "tie over" dressing. The dressing will be removed at day 5, and then it will be removed every 3 days up to the 14th day.
This group is comprised of the patients' wound halves that will receive skin micro grafts. To obtain this grafts the investigators will use "Xpansion micro-autografting" system. They will use 0.8 x 0.8 mm skin grafts with a graft to graft distance of 4mm (1:50 expansion).This half will be covered with a special hydrogel dressing with keratinocyte growth factor (Epilife medium with calcium) 1.5ml for each 14 square centimeters of the wound. This half will be covered with a wet adhesive foam dressing and then it will be covered up with a non-adherent interface dressing (tegaderm). The dressing will be removed at day 5, and then it will be removed every 3 days up to the 14th day. Each time of dressing change only the non-adherent interface dressing will be removed, and the area will be bathed with keratinocyte growth factor solution.