Intravenous Fluids in Hospitalised Children
Hypokalemia, Hyponatremia, Hypernatremia
About this trial
This is an interventional treatment trial for Hypokalemia focused on measuring Isotonic, Hypotonic, Intravenous fluids
Eligibility Criteria
Inclusion Criteria:
- Acutely ill hospitalised children
- Need for intravenous fluid therapy
Exclusion Criteria:
- An initial plasma sodium concentration of lower than 130 mmol/L
- An initial plasma sodium concentration of higher than 150 mmol/L
- An initial plasma potassium concentration of lower than 3.0 mmol/L
- Need for 10% glucose solution
- Diabetes
- Diabetes insipidus
- Diabetic ketoacidosis
- Renal disease that needs dialysis
- Protocol-determined chemotherapy hydration
- Severe liver disease
- Inborn errors of metabolism that need protocol-determined fluid therapy
Sites / Locations
- Oulu University Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Isotonic solution
Hypotonic solution
Plasmalyte Glucos 50 mg/mL; total daily fluid requirements are estimated using the Holiday-Segar method plus possible dehydration (according to child's weight loss during acute illness); intravenous fluids are administered using delivery pumps programmed for an hourly infusion rate (mL/hour); intravenous fluids are administered as long as needed during hospitalization, but no longer than seven days after admission.
0.45% saline in 5% dextrose; total daily fluid requirements are estimated using the Holiday-Segar method plus possible dehydration (according to child's weight loss during acute illness); intravenous fluids are administered using delivery pumps programmed for an hourly infusion rate (mL/hour); intravenous fluids are administered as long as needed during hospitalization, but no longer than seven days after admission.