Adjunctive Nitrous Oxide During ED Incision and Drainage of Abscess
Abscess
About this trial
This is an interventional treatment trial for Abscess focused on measuring Nitrous Oxide, Abscess, Incision and drainage
Eligibility Criteria
Inclusion Criteria:
- All patients 18 years of age or older with cutaneous abscesses located on the trunk or extremities that required I&D were approached and offered participation in the study. Need for I&D was left to discretion of treating physician.
Exclusion Criteria:
- Abscesses larger than 5 cm in any dimension
- Abscesses located on the face, neck, scalp, hands, feet, perianal, rectal, or genital areas.
- Subjects with underlying conditions that could affect ventilation, perfusion, or metabolism including intubated subjects, history of COPD, subjects with clinical signs of cardiopulmonary instability, major trauma, shock, sepsis, ASA class 3, 4, and 5.
- Those unable to provide informed consent, nursing home residents, age less than 18 years, non-English speaking, pregnant women, subjects under police custody, or physician discretion.
Sites / Locations
- Einstein Medical Center Philadelphia
Arms of the Study
Arm 1
Arm 2
Experimental
Experimental
Nitrous Oxide
Oxygen
Patients undergoing incision and drainage of abscess will undergo an initial medical assessment including the history, physical examination, and vital signs. The patients will then receive Nitrous Oxide gas via a gas mixer device while undergoing standard incision and drainage of cutaneous abscess using lidocaine local anesthesia administered subcutaneously. The device will mix and deliver nitrous oxide and oxygen in a 1:1 ratio, at a fixed concentration of 50%/50%. The on demand valve requires patient inspiration to trigger dosing.
Patients undergoing incision and drainage of abscess will undergo an initial medical assessment including the history, physical examination, and vital signs. The patients will then receive 100% oxygen gas via the Nitrous Oxide gas mixer device while undergoing standard incision and drainage of cutaneous abscess using lidocaine local anesthesia administered subcutaneously. The device will deliver only oxygen at a fixed concentration of 100%. The on demand valve requires patient inspiration to trigger dosing.