Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain
Pain, Acute, Pain, Chronic, Pain, Neuropathic
About this trial
This is an interventional treatment trial for Pain, Acute focused on measuring anesthesia, thoracic surgery, thoracic paravertebral block, ketamine
Eligibility Criteria
Inclusion Criteria:
- American Society of Anesthesiologist physical status 1-3
- Scheduled for elective video-assisted thoracic surgery
- Able to operate a patient-controlled analgesia device (PCA)
Exclusion Criteria:
- History of morphine allergy
- History of bupivacaine allergy
- Contraindication for ketamine infusion
- Contraindication for thoracic paravertebral block
- Anticipated postoperative positive pressure ventilation
- Body mass index more than 35
- Any known psychiatric disorder
Sites / Locations
- Siriraj Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Ketamine
Normal saline
Participant allocated to this arm will receive intravenous ketamine infusion starting after the induction of anesthesia until the end of the surgery at the beginning of skin closure Participant will receive an ultrasound-guide thoracic paravertebral block using 0.5% plain bupivacaine prior to the induction of anesthesia
Participant allocated to this arm will receive intravenous normal saline solution infusion starting after the induction of anesthesia until the end of the surgery at the beginning of skin closure Participant will receive an ultrasound-guide thoracic paravertebral block using 0.5% plain bupivacaine prior to the induction of anesthesia