Assessment of Glycemic Control in Patients With Type 2 Diabetes Mellitus and Late Stage Chronic Kidney Disease
Diabetes, Kidney Diseases
About this trial
This is an interventional prevention trial for Diabetes focused on measuring Chronic Kidney Disease
Eligibility Criteria
Inclusion Criteria:
- 18 years and older with ability to speak and understand English
- Established diagnosis of type 2 Diabetes Mellitus
- Chronic Kidney Disease (stages 3b, 4 or 5, eGFR (Glomerular Filtration Rate) < 45 ml/min, and not on dialysis) documented within 3 months of enrollment
Exclusion Criteria:
- Type 2 Diabetes Mellitus.
- Patient with End stage kidney disease on Dialysis.
- Presence of Hemoglobinopathies.
- Red blood cell transfusion in the last 12 weeks.
- Hb < 9 g/dL documented within 3 months of enrollment - Dosing with an erythropoiesis stimulating agent is acceptable but dose must be stable for two months.
- Use of acetaminophen on a daily basis.
- Systemic steroid treatment in the past 12 weeks.
- Greater than 50% dose change in diabetes medications or new diabetes medications started in the previous 8 weeks.
- Currently pregnant.
Sites / Locations
- Northwell Health (Division Endocrinology and Nephrology)
Arms of the Study
Arm 1
Experimental
Continuous glucose monitoring
If subjects meet inclusion criteria then they will return to the research site on Day 1 to place Freestyle Libre Pro device by the research staff for 14-day monitoring. Subjects will be advised to return to the research site on Day 14 to remove the CGM device for analysis. On Day 14, blood will be drawn for HbA1c and fructosamine, The blood drawn for this research will be approximately 10-15 milliliters. There are no drug washout periods. Subjects will continue to take all their medications and/or insulins as prescribed by their doctor. Baseline data including age, race, ethnicity, past medical history, home medication list, and diabetes related laboratory data will be collected.